DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TkR99D and LOC100489992

DIOPT Version :9

Sequence 1:	NP_001263092.1	Gene:	TkR99D / 43551	FlyBaseID:	FBgn0004622	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_002941889.1	Gene:	LOC100489992 / 100489992	-ID:	-	Length:	414	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	115/356 - (32%)
Similarity:	198/356 - (55%)	Gaps:	24/356 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FGQELA----LSTSSFNHSQTLSTDLPAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSILFG 109
            ||..||    ::.:|||.:.:      .:|:.|..||  .|..|:.:....|    |.|..:.:.
Frog    28 FGTLLAKFQIMNRTSFNFTDS------RIGEWERFAE--LAKYESDAQKPTV----QALLIVAYS 80

  Fly   110 GMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYC 174
            .:::::..||::|..:||..|||.:.|:.|||||:::|.|::.||..|.....::|.|.||:..|
Frog    81 VIIVMSLFGNMLVCHVVMKNKRMHSATSLFIVNLAVSDIMITLLNTPFTLVRFVNSTWVFGKEMC 145

  Fly   175 KLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYR 239
            .:|:|:...|:..|..||.||::||:..|:.||:||||....:...:.||:.:|..|.|..|..:
Frog   146 HISRFVQYCSLHVSTLTLTAIALDRHQVILNPLKPRMSLSKGVLCISFIWVMATCFSLPHAIYQK 210

  Fly   240 TEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKT 304
            ......|....|::|.|::|: |::  ......::...:|.|.||::.:|:.|||:..:||....
Frog   211 LFRYNYRENKVRSLCIPDFPE-PSD--LFWKYLDLSTFLLLYLLPLLIITIAYSRLAKKLWMRNA 272

  Fly   305 IGECTPRQ-VENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYW 368
            ||:.|..| :.:.::|::.:||:::||::||:||.|.:.|.::.|.....|:    ..||.|::|
Frog   273 IGDITTEQYITHRKNKKKSIKMLVLVVVVFAVCWFPLNCYVVLISSLGIKTK----NALYFALHW 333

  Fly   369 LAMSNSMYNPIIYCWMNSRFRYGFKMVFRWC 399
            .|||::.|||.||||:|..||...|.:...|
Frog   334 FAMSSTCYNPFIYCWLNESFRLELKSLLSMC 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tm_4	113..396	CDD:304433	98/283 (35%)
TkR99D	NP_001263092.1	7tm_1	118..381	CDD:278431	90/263 (34%)
LOC100489992	XP_002941889.1	7tmA_GPR83	73..357	CDD:320511	98/290 (34%)
		TM helix 1	74..100	CDD:320511	6/25 (24%)
		TM helix 2	107..132	CDD:320511	11/24 (46%)
		TM helix 3	145..175	CDD:320511	11/29 (38%)
		TM helix 4	186..207	CDD:320511	5/20 (25%)
		TM helix 5	237..266	CDD:320511	8/28 (29%)
		TM helix 6	286..316	CDD:320511	11/29 (38%)
		TM helix 7	325..350	CDD:320511	14/24 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314830at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920