Protein Alignment TkR99D and grpr

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002938295.1
• Gene: grpr / 100486428
• XenbaseID: XB-GENE-1013137
• Length: 384
• Species: Xenopus tropicalis
• Alignment Length: 406
• Identity: 112/406 - (27%)
• Similarity: 184/406 - (45%)
• Gaps: 70/406 - (17%)

  Fly    46 LPDFGQELALSTSSFNHSQTLSTD---LPAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSIL 107
            |.|...:.||::|..|.|...|:|   .|.|                 ::| :||         :
 Frog     8 LLDLEADFALTSSCLNQSSNHSSDDWFYPGV-----------------TYA-IVP---------V 45

  Fly   108 FGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEF 172
            :|.::::...||:.::.|..|.|.||.|.|.||.:|::.|.::.......:....|...|.||..
 Frog    46 YGIIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASRFLADKWLFGRV 110

  Fly   173 YCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPR----MSKRCNLAIAAVIWLASTLISCP 233
            .|||..||.:.|:..|||||.|::.|||.||:||:..:    ::|.|  ..||:||:.|..::.|
 Frog   111 GCKLIPFIQLTSVGVSVFTLTALAADRYTAIVRPMDIQANNALTKIC--IKAALIWILSMTLAIP 173

  Fly   234 MMII-----YRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYS 293
            ..:.     :..:|:.|..:|    |.| :|.....|..:.|..:.||.   |.:|:..::|.|.
 Frog   174 EAVFSDMHPFYDKEINVTFVS----CAP-YPHSNGLHPRIHSTTSFLIF---YVIPLSIISVYYY 230

  Fly   294 RVGIELWGSKT----IGEC-TPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAI 353
            .:...|..|.:    .|.. ..||:|   |::|:.|.::|.|.:||.||||.|..::..|.:.:.
 Frog   231 FIAKNLMRSASNMPVEGNVHVRRQIE---SRKRLAKTVLVFVGLFAFCWLPIHIIYLYRSYHYSE 292

  Fly   354 TEAP---FIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWC---LFVRVGTEPFSRR 412
            .:..   :|..:...:  ||.:||..||.....::..||..|......|   |.||  |:...|.
 Frog   293 VDTSVLHYISSICARV--LAFTNSCVNPFALYLLSKSFRKQFNNQLFCCRPRLIVR--TQSMGRS 353

  Fly   413 ENLTSRYSCSGSPDHN 428
               |:|.:...|.:|:
 Frog   354 ---TTRMTSLKSTNHS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	87/306 (28%)
		TM helix 1	103..129	CDD:320512	4/25 (16%)
		TM helix 2	136..162	CDD:320512	5/25 (20%)
		TM helix 3	174..204	CDD:320512	16/29 (55%)
		TM helix 4	215..236	CDD:320512	7/20 (35%)
		TM helix 5	269..298	CDD:320512	7/28 (25%)
		TM helix 6	317..347	CDD:320512	12/29 (41%)
		TM helix 7	360..385	CDD:320512	6/24 (25%)
grpr	XP_002938295.1	7tmA_GRPR	40..332	CDD:320252	90/316 (28%)
		TM helix 1	41..67	CDD:320252	7/35 (20%)
		TM helix 2	74..100	CDD:320252	5/25 (20%)
		TM helix 3	112..142	CDD:320252	16/29 (55%)
		TM helix 4	154..174	CDD:320252	7/21 (33%)
		TM helix 5	206..231	CDD:320252	7/27 (26%)
		TM helix 6	256..286	CDD:320252	13/32 (41%)
		TM helix 7	300..325	CDD:320252	7/26 (27%)