Protein Alignment TkR99D and qrfprl2

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002935352.5
• Gene: qrfprl2 / 100486271
• XenbaseID: XB-GENE-952811
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 344
• Identity: 102/344 - (29%)
• Similarity: 169/344 - (49%)
• Gaps: 39/344 - (11%)

  Fly   102 VLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSD 166
            ||:.|:|    |:|..||.:||:|::..|.||||||.||.:::.:|.:|:...:.|.....:.|:
 Frog    51 VLYIIIF----ILALFGNSLVVYIIIRKKAMRTVTNIFICSMACSDLLVTFFCIPFTLLQNISSE 111

  Fly   167 WPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAA-----VIWLA 226
            |..|.|.||:..||...::.||..|:..|:::||..|:.||:   .||....|.|     .:|..
 Frog   112 WLGGRFVCKMVPFIQTTAVVASTLTMTCIAVERYQGIVHPLK---MKRQYTNIRAYKMLGCVWSV 173

  Fly   227 STLISCPMMIIYRTEEVPVRGLSN--RTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMT 289
            :.::..||:.: :|.||....|.|  ...|...|.|     ..:...|.|.|::..:.:|:.:|.
 Frog   174 AIVVGSPMLHV-QTLEVKYDLLYNLYHVCCLESWSD-----VELRRAYAIFILVALFLVPLAAML 232

  Fly   290 VTYSRVGIELWGSKTIGECT-------PRQVENVRSKRRVVKMMIVVVLIFAICWLPFH------ 341
            :.|:|:|.|||..|.:|:|:       ....:..|.|:|.|.||::|||.|..||.|||
 Frog   233 LLYTRIGYELWIKKRVGDCSVLNTLSRNEMAKITRKKKRAVMMMVIVVLFFTACWAPFHVVHILF 297

  Fly   342 SYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLF-VRVG 405
            .|..:...|..:|    ::.:...:..:...||..||::|.:||..|:.....:. :|.| .:..
 Frog   298 EYNNLEDEYDDVT----VKMIVAIVQAVGFFNSFNNPVVYTFMNENFKKSLVAIL-FCHFRAQEP 357

  Fly   406 TEPFSRRENLTSRYSCSGS 424
            .||..:|::..|.....|:
 Frog   358 VEPADKRDSQQSERPKGGT 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	95/309 (31%)
		TM helix 1	103..129	CDD:320512	10/25 (40%)
		TM helix 2	136..162	CDD:320512	7/25 (28%)
		TM helix 3	174..204	CDD:320512	10/29 (34%)
		TM helix 4	215..236	CDD:320512	5/25 (20%)
		TM helix 5	269..298	CDD:320512	8/28 (29%)
		TM helix 6	317..347	CDD:320512	16/35 (46%)
		TM helix 7	360..385	CDD:320512	5/24 (21%)
qrfprl2	XP_002935352.5	7tmA_QRFPR	48..343	CDD:320333	95/308 (31%)
		TM helix 1	48..74	CDD:320333	11/26 (42%)
		TM helix 2	81..107	CDD:320333	7/25 (28%)
		TM helix 3	119..149	CDD:320333	10/29 (34%)
		TM helix 4	162..183	CDD:320333	4/20 (20%)
		TM helix 5	212..237	CDD:320333	6/24 (25%)
		TM helix 6	267..297	CDD:320333	15/29 (52%)
		TM helix 7	312..337	CDD:320333	5/24 (21%)