Protein Alignment Vps13B and VPS13

DIOPT Version :9

• Sequence 1: NP_651753.2
• Gene: Vps13B / 43550
• FlyBaseID: FBgn0039727
• Length: 3731
• Species: Drosophila melanogaster
• Sequence 2: NP_013060.1
• Gene: VPS13 / 850619
• SGDID: S000003963
• Length: 3144
• Species: Saccharomyces cerevisiae
• Alignment Length: 4144
• Identity: 738/4144 - (17%)
• Similarity: 1340/4144 - (32%)
• Gaps: 1530/4144 - (36%)

  Fly     4 LESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELS 68
            |||....:|...:..||:||......|.:|.|:|..:||.||.:.| :.||||:::.||.:.:|.
Yeast     2 LESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRKDCL-DSLNLPIDVKSGILGDLV 65

  Fly    69 ILVPWTKLMSEPVKIVINTIEFVAKLPDSESKQR-----RASFQREQRRKSKRESVEQPD--QTK 126
            :.|||:.|.::||||:|.....:.. |.||..:.     :.:|:.:.|:.|:.|...|..  .|:
Yeast    66 LTVPWSSLKNKPVKIIIEDCYLLCS-PRSEDHENDEEMIKRAFRLKMRKVSEWELTNQARILSTQ 129

  Fly   127 SPGPASSS-----------SVVNKIINNINLQCHNIILKYVEDDIV-------VSMNVQTLNFSS 173
            |....|||           |:..|||:|:.:...||.|:|.:.|.:       |.:.:..|:..|
Yeast   130 SENKTSSSSSEKNNAGFMQSLTTKIIDNLQVTIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVS 194

  Fly   174 AGEDWKPTMVDIHPVSVVMRKLLQVSDLTICL-------------------------------DK 207
            ...:|.|:.:||  ...:..|||.::.|  ||                               .|
Yeast   195 TDSNWAPSFIDI--TQNITHKLLTLNSL--CLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASK 255

  Fly   208 RNTAGRIEVCQEPVLYRCTLECRVLRKYNANTVSTTST----------TRIGVFTKSLDIN---- 258
            .:||.:.:...:||        ..|.|.:.|.:.:|..          ...|:.....:.|
Yeast   256 NSTAPKHQYILKPV--------SGLGKLSINKLGSTEEQPHIDLQMFYDEFGLELDDTEYNDILH 312

  Fly   259 -VSSLQFPMVMRLVKMLLELKPA-EFEDDPQNPEDQEAVAEGSESQQGTESAGRSVFWWAWSLLP 321
             :||:|   :.::.|...:.:|: ...::|.......|....:|..:..:       .|.|
Yeast   313 VLSSIQ---LRQITKKFKKARPSFAVSENPTEWFKYIAACVINEIHEKNK-------MWTW---- 363

  Fly   322 SFDTEAPSSSCDTPTGHAFDLGVYAEELNFQLKNSEYFTDQSMGGIKRIRYTPILRISLGGLY-- 384
                |:....|:.   ......::.|:|  :|||.|          ..:| .||....|..|:
Yeast   364 ----ESMKEKCEQ---RRLYTKLWVEKL--KLKNLE----------APLR-DPIQEAQLSELHKD 408

  Fly   385 --YERTIL----KECDWANVKAGL--------SSMCMEPLGAYRS-----------------DDL 418
              |:..||    .:..:|..|.|:        :|..:||..:.:|                 .:.
Yeast   409 LTYDEIILFRSVAKRQYAQYKLGMTEDSPTPTASSNIEPQTSNKSATKNNGSWLSSWWNGKPTEE 473

  Fly   419 VDRNLVNTQEFQQERSFIDKSLFDENYMFAERSWCSYNYADYVARNTDEYMLFRSPVLAFDVIEH 483
            ||.:|:.|:|.:||  ..|...|||                    |.|     :.|||
Yeast   474 VDEDLIMTEEQRQE--LYDAIEFDE--------------------NED-----KGPVL------- 504

  Fly   484 RVPKPSSHPVAESQLRDLGVRIQYR---LLSAGITFHFSQSFVQVKKVISDLIRPYDYPGYRSES 545
            :||:.               |::.|   ||..|       ||...||
Yeast   505 QVPRE---------------RVELRVTSLLKKG-------SFTIRKK------------------ 529

  Fly   546 MKDEDRGVPEPENKNSEMTIPDLEYLMGLVPTCNYKIELRNIVVQLYPRQQQDESSAINQHQLTT 610
                      .:|.|           :|.:...|.|::.           .|...|.::..||.
Yeast   530 ----------KQNLN-----------LGSIIFENCKVDF-----------AQRPDSFLSSFQLN- 561

  Fly   611 TVRQSLLPYLQLKISLVEGTMCGPVNPVRLVQLITHLEEKPRDVVNACYNCFHFNVKNLALMIMN 675
                        |.||.:|:                        .||.|       |:: :.:.|
Yeast   562 ------------KFSLEDGS------------------------PNALY-------KHI-ISVRN 582

  Fly   676 TTPDNGRAKLLNIPRVQVNWNRLLAPHLWRQNEAPLETSEIKSEIITLEFSKRELIIAKRLVPLI 740
            ::.|....                      .|.|..|..|....::...|         .|.||.
Yeast   583 SSKDQSSI----------------------DNHATGEEEEEDEPLLRASF---------ELNPLD 616

  Fly   741 SSFSGQDLCDLAHIVANVNVNSDVIKLQSVGTKLNLVYHKYHTHLAAVGSLQGVHTDAVHTKMNI 805
            .             :|:.|:|   |||..:     .|:  ||.|.
Yeast   617 G-------------LADSNLN---IKLLGM-----TVF--YHVHF-------------------- 638

  Fly   806 RNVVLSTSKNADNKWLEMQCQFPLEEVHSEQEKIPGTVVCLWLEPFRITTDIYLLQFLNFSDNSG 870
                                   :.|||                           :|...|
Yeast   639 -----------------------ITEVH---------------------------KFFKAS---- 649

  Fly   871 RQITKDKEVETDLESVNQSEPPITQSVSNYSTISASAIAFNDFQPRRISRNNSRKISVPEETVHL 935
                 ::.:||....||.:|    .:|..::|.:...|               ..:....:||::
Yeast   650 -----NQHMETIGNIVNAAE----ATVEGWTTQTRMGI---------------ESLLEDHKTVNV 690

  Fly   936 SSERDERHTQAEPLTIPVANKPQPSNFDTTDFVKRLTKMVVLVEIAQAKIDVCEVMMRKTPGHTD 1000
            |.:     .||..:.:|:    .|.::||.                      |.::   ..||..
Yeast   691 SLD-----LQAPLIILPL----DPHDWDTP----------------------CAII---DAGHMS 721

  Fly  1001 VEYTSIRLPHMKVKSGNCEAIQRGNIRGVIPVASNTELLNWVFDLNEFN-VCYRRANV----TEM 1060
            :  .|..:|..|:|          .|:.:.|...:.      .|.||.| :.:.|..:    |::
Yeast   722 I--LSDLVPKEKIK----------EIKELSPEEYDK------IDGNEINRLMFDRFQILSQDTQI 768

  Fly  1061 IIAP-VRTTITLALSFKTSDKVDGSKGKED-KCANTCSINVHVDMS---------AINIFAQRVK 1114
            .:.| :::||         .|::.:....| :..:...:.:.||:|         .|.:|....:
Yeast   769 FVGPDIQSTI---------GKINTASSTNDFRILDKMKLELTVDLSILPKAYKLPTIRVFGHLPR 824

  Fly  1115 L-------LHEHCL-IISKMYGSLCPDEPAS----KWQTG---KMKPRLEVYTGSA-------QN 1157
            |       .::..: :|:....|:..||..:    .:.:|   :||.::::...:.       |.
Yeast   825 LSLSINDIQYKTIMNLIANSIPSMIDDEENNGDYVNYSSGSEKEMKKQIQLQLKNTLKALENMQP 889

  Fly  1158 YPVIKEFLELDPNFEAPKVKSAPKSSVILFCQWTIPRISFEMENSNDFKHSKIVMSL--EDLLLN 1220
            ..:.::||||  :|:..:.|                 |:|.....||.::|:.::.:  :.|..|
Yeast   890 LQIEQKFLEL--HFDIDQAK-----------------IAFFQCIKNDSRNSEKLVDILCQRLNFN 935

  Fly  1221 IDKHSDFNKITTKIENFGLNYYEEKHEEW-EKIDDLHIKMLGDSTNLPLISVVITTVSLEDL--- 1281
            .||.:       |..|..|..:....|:: |..|:...|      ||....|...|.|.:||
Yeast   936 FDKRA-------KEMNLDLRVHSLDVEDYIELTDNKEFK------NLISSGVEKVTRSQKDLFTL 987

  Fly  1282 -YAKIGARNPHNKQHTISEVLIEVQPIEMVLNLDQITEFMVPICEVLEIIGNS-ASAQSANKPSA 1344
             |.::....|||      :.|||:...::|:::.::...:.| ..||.::..: .:....|.|..
Yeast   988 KYKRVQRIVPHN------DTLIELFDQDIVMHMSELQLVLTP-RSVLTLMNYAMLTFTDPNAPEM 1045

  Fly  1345 P-------------VPSKITTVQDLPMVHL--NSKGI-YVYLPLSTGKKSCSVLL-------LRI 1386
            |             .|.||.....:..|::  |...| ...|.||.|:.: .|||       |::
Yeast  1046 PADVLRHNKEDRDDAPQKINMKIKMEAVNVIFNDDSIKLATLVLSAGEFT-MVLLPERYNINLKL 1109

  Fly  1387 ESIQLTPSLENPLVRQLV-RPDIYQKAAELNMLSTPGALVEDRQYELSVRRVSLSTGNWKQTQEY 1450
            ..::||........|..| |..|..|..||              .|||......:|    .|::|
Yeast  1110 GGLELTDETNESFSRDSVFRKIIQMKGQEL--------------VELSYESFDPAT----NTKDY 1156

  Fly  1451 R--IEKTLASKHDNPAFEWNNQSQSTELDHMEIFKDFDFIMIYAPAISYDRFLVCGQSVEYNCAT 1513
            .  ::.:..|.|.|        ...:.::.|..|    |.......:|:||    .:...||.|.
Yeast  1157 DSFLKYSTGSMHVN--------FIESAVNRMVNF----FAKFQKSKVSFDR----ARLAAYNQAP 1205

  Fly  1514 DFVASLNTHQISLISCIIVRAQRLGCIIDQVCVKNAELPKARSHKTLGNISKYNSVDNSIYFPAD 1578
            . :.::|..::.    |:::|                 |..:..|.:|  ::.|:.|...::..:
Yeast  1206 S-IDAVNNMKMD----IVIKA-----------------PIIQFPKLVG--TQENNYDTMRFYLGE 1246

  Fly  1579 PKVFKKDTWIPKSSKKLVSERLSYTNASTSFTDAKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLA 1643
            ..:..|.:.|.:|.|                                .:.|.||.|....|.:|
Yeast  1247 FFIENKFSVIDESHK--------------------------------INHIKLGVREGQLSSNL- 1278

  Fly  1644 AEEINRSGRQPFVLSYPSSVSFVAGIFVLKIYDVLELEELERPVMKPLFLMTVSQPSFMSTQNFK 1708
              ..:.|.:|.::         |..|.:|...|...|.:.:.|.:|             .|.||:
Yeast  1279 --NFDGSSQQLYL---------VENIGLLFNIDRDPLPQDDTPELK-------------VTSNFE 1319

  Fly  1709 AAVTQASIFNVNISVAK----ADVDGKVDSERFNESVFATLPGQLGSSGIPPPLLTIKTQYDRLH 1769
            :       |.::::..:    .::..|| |..||  :.....|:.|..|
Yeast  1320 S-------FALDLTENQLTYLLEISNKV-SSAFN--ITDENSGESGGKG---------------- 1358

  Fly  1770 QKEVDVELRKPILLRICENTIKQLASDVFRIYTVLHETPCFNVRSPRPVPEGSQLRQLKMNCYNA 1834
                  |::.|      ......|:|:..|..|            |:.: :||.    |.|..|.
Yeast  1359 ------EIKSP------SPDPASLSSESERTAT------------PQSL-QGSN----KSNIKNP 1394

  Fly  1835 DR----FHLSCDRITAKFYDEERSY----KCSFVWLDVSTRIKFSSRPQKAVIRSNIGSFYVQSG 1891
            ::    |.....:|....|::.:..    .|..      |||.|..      |..::|
Yeast  1395 EQKYLDFSFKAPKIALTLYNKTKGVTSLNDCGL------TRIMFQD------IGCSLG------- 1440

  Fly  1892 EKMLLHPLLMRLSVDLVSEPWSEELLVNATLKLNYLHIDAGVFSILQLQKAQQGVNRIREYADRE 1956
                                          || |...:|.      |...|...:..:|...|.:
Yeast  1441 ------------------------------LK-NDGTVDG------QAHVAAFRIEDVRNIKDNK 1468

  Fly  1957 WQQFLRSRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRAGAFQFVYLNSES- 2020
            ..:.:        ||..:        ..::.:..|.|          .:|..|....:.:..:|
Yeast  1469 HTELI--------PKSKN--------KEYQFVANISR----------KNLEVGRLLNISMTMDSP 1507

  Fly  2021 --VLPMPYQVQIIKKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRMEYF----SETHET 2079
              :|.|.|.|.:                                       .|:|    |::||.
Yeast  1508 KMILAMDYLVSL---------------------------------------KEFFDAIMSKSHEN 1533

  Fly  2080 FLHYCDFMLSETSTKQLTPPDRPICATI----------WRVVILQ-SLISVDGTCFEGSEDEDLS 2133
            .|:|.:      :|.| .|.::.|..::          :.|.|:: :||.:...|...||    :
Yeast  1534 NLYYPE------NTNQ-KPENKAIVESVQEGGDVTKIQYSVNIIETALILLADPCDMNSE----A 1587

  Fly  2134 IEYLQSDFKVDENNDFILHPKVLVGCMRIDTVFRAEKVPKLQLLLCCQDIELNFVNQTDNTGELP 2198
            |.:....|.|.:.|              |.|| .|..|......:...:.:|..::...::..:.
Yeast  1588 ISFKIGQFLVTDQN--------------IMTV-AANNVGIFLFKMNSSEEKLRLLDDFSSSLTID 1637

  Fly  2199 KQLNKYRLRQTPNITQTFLTVHVEDLQMHSRIYSRNDFSLQTEMRARVKCLDYGFLNML------ 2257
            |:      ..||....|.:.:.|:.|.|  || |..|..|...:..||..|    ||.:
Yeast  1638 KR------NSTPQTLMTNIQLSVQPLLM--RI-SLRDIRLAMLIFKRVTTL----LNKMTEKEDN 1689

  Fly  2258 ----DVLEPMKFSSYVRLTDYPRSL--VQANFLVDKLRLNCGPHVIHTLLSSKYHWQEVLQQKDV 2316
                :..:.::||.     ::.|.|  :..:.|.::.|.:                    |..|.
Yeast  1690 GEEEESTDKIQFSH-----EFERKLAVLDPSILGERSRAS--------------------QSSDS 1729

  Fly  2317 RHVLMPKLVIVNRIQTP----ISFGQTNTVEKIPVNPGEVQLYHFRSCSHVQELTFFITNPKTLL 2377
            ..:.:|..::.|.....    :.|.....|.::|:..           .:|.|:|   .:.|
Yeast  1730 ESIEVPTAILKNETFNADLGGLRFILIGDVHEMPILD-----------MNVNEIT---ASAK--- 1777

  Fly  2378 VDSSDSVHIALKFEDEEKIHNLRVGEYCITLKLAKLSTTQIYILVKGQIELVSMVPFNLVTEFRE 2442
             |.|.........|....|.|.....:...|::..::    :.|.||..|:.....|:::|: |.
Yeast  1778 -DWSTDFEALASLETYVNIFNYSRSSWEPLLEMIPIT----FHLSKGHSEMDPAFSFDILTQ-RI 1836

  Fly  2443 EEI-----------NYDESTPPEHLLLSKERSSYYQ---NVKRNADINMRLKLTAGLGRGRTGDI 2493
            .||           :...|...|..|.|:.....||   :.:.:.|:.::.|.|..   .:...:
Yeast  1837 AEITLSARSIAMLSHIPASLTEELPLASRVSQKPYQLVNDTELDFDVWIQDKTTED---NKNEVV 1898

  Fly  2494 PLKTNNNLPWLVKVPTQSAQQFISIWVRILREDIKMDKPAEDFQPQKIL-ICIW----------- 2546
            .||.|.:|||          :| ..| |.:||.:.:||      .:.|| :|:.
Yeast  1899 LLKANTSLPW----------EF-EDW-RSIREKLDIDK------SKNILGVCVSGQNYKTIMNID 1945

  Fly  2547 -------------PIFEICNMLSCAVK---------------ATESTTGESSTIEAM-------- 2575
                         |...:.|.:.|..:               ..|:||  |:.||.:
Yeast  1946 ATTEGENLHVLSPPRNNVHNRIVCEARCDENNVKIITFRSTLVIENTT--STEIELLVDSKDPNK 2008

  Fly  2576 -GGRWALNTATTHATEHNIGFTFSGILRGSSKDEYSLMLRTMDWHKFFYYDPTVW--TIENALHK 2637
             ..::|:....:.:......:.....:|.:|:|.|....:|:.|........:::  :.|::..:
Yeast  2009 PSLKYAIKPHQSKSVPVEYAYDSDIRIRPASEDIYDWSQQTLSWKSLLSNQMSIFCSSKEDSNQR 2073

  Fly  2638 LGKSSKRKWPLNDP-------EELRVSRVLDFENAF--DVKYQTKATREFSCCQGLDVTAWGMFI 2693
            .......|:...:|       .::.||..:..||..  |:.:
Yeast  2074 FHFEIGAKYDEREPLAKIFPHMKIVVSASMTIENLLPADINF----------------------- 2115

  Fly  2694 NGTGLYVAIFMIQEQARLD-LK-ANSLQMMP-KLKSAFTIDVRFDNGWKSSTPICLEDFTQKSSS 2755
                   :||..:|:.|.| || ..|:::.. .|.|...:.|:......|::...:.:...||..
Yeast  2116 -------SIFDKREEKRTDFLKTGESMEVHHISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPL 2173

  Fly  2756 NAGRSLYLRYNSFVDIVIVERDEVLRLILEYRQEDDGR-RLFKLRSKFVFTNFTD----VVLNAL 2815
            |...||.|..:.         .:.|.|.|:|:..|..| ::.::.|.::..|.||    :..:.|
Yeast  2174 NPEDSLSLTLSG---------GQNLLLKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLL 2229

  Fly  2816 TLAMDH--KENSTREEVEAYSICKKARSLVSSESTKNCSGNAMDVFYDLNAHKAKHNCDTAFVYF 2878
            .:|...  .||..|     |:|.|     :.|...::...|...:.:..:...:|.:.|
Yeast  2230 NIAQSKILLENEKR-----YTIPK-----MFSFDKEDDKSNRARIRFKESEWSSKLSFD------ 2278

  Fly  2879 VCFSVGGSREISIPIPLAVPFTRRCFSLQAGPESIPLMITLIEKDNVHYLNVFRDTAPAIVISNN 2943
               ::|.|.:.|:.|             :...:...|.|.:.|....:.|:...:.||..:|||.
Yeast  2279 ---AIGQSFDASVRI-------------KNKEQESNLGINISEGKGKYLLSKVIEIAPRYIISNT 2327

  Fly  2944 TNVKFIVAQTSASE----NSNVS-----CTN-------SEFVGRNFEWNQ--------------- 2977
            .::...|.:|.:.:    .||::     ..|       .:|:|.:..|:|
Yeast  2328 LDIPIEVCETGSMDVQQIESNITKPLYRMRNIVDKQLVLKFLGGDSNWSQPFFIKNVGVTYLKVL 2392

  Fly  2978 -----------LVLPHSNCYYTP-------PQMYANFPDVEFTMCNLS----LAVYKD------- 3013
                       ::|..:..:...       |....||.|.:|......    ...|||
Yeast  2393 KNSRHKLLKIEILLDKATIFIRIKDGGDRWPFSIRNFSDHDFIFYQRDPRKVSDPYKDDQSNESS 2457

  Fly  3014 ---------KLCAKN--KIAWS----------------------------KPIRTDK-SWQK--- 3035
                     ::.:|:  ..||.                            .|:|.|| |..|
Yeast  2458 SRSFKPIFYRIPSKSIMPYAWDFPTAKEKYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAP 2522

  Fly  3036 --FLHVPHHGDVKVVVCDKHRAIRLNIYYIAQQLEFSVKDLRSRLTKPENVLMPSQEQAAPRPDE 3098
              .|||....|::.:|...::| .:.:|.:
Yeast  2523 IVGLHVVADDDMQALVIVNYKA-NVGLYKL----------------------------------- 2551

  Fly  3099 SSEQENDTKRVTLPNMVTCAHFNEECESKTQTRIKIFIKSFVFSLQTDNRENDFVKTEVCNIYAD 3163
            .:.....|..|::.:.||.....::.:.|..|:|.:..|....||.....:      |:..|...
Yeast  2552 KTASATTTSSVSVNSSVTDGFVQKDEDEKVNTQIVVSFKGVGISLINGRLQ------ELLYINMR 2610

  Fly  3164 DSMLIYDDDDDQRELRLQLPNLQVDNQLYSSGKY-----------------DFPVLLCAEKLYRR 3211
            ...|.|::....:....::..:|:||||: ||.|                 :.||:  :..:.:.
Yeast  2611 GIELRYNESKAYQTFSWKMKWMQIDNQLF-SGNYSNILYPTEIPYTEKEIENHPVI--SGSISKV 2672

  Fly  3212 NCSLPQVYDLDHV------YKQQAQRTPV-SLFTFI--------------FYQDEMQLQNVRCQI 3255
            |.||..|....||      :..|.....: ::..||              .|.:|:||.:|....
Yeast  2673 NDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPGSPWIMDSRDYKYDEEIQLPDVSELK 2737

  Fly  3256 PPFRVYIEDAYLNQLLEALVECEPSNCVYSPPVEQDQILLPAGMTLLPDQVVAQSLY-------- 3312
            ....:|.|          :...:|: .::...:..|:|  ..|:....::..:.|||
Yeast  2738 TAGDIYFE----------IFHIQPT-VLHLSFIRSDEI--SPGLAEETEESFSSSLYYVHMFAMT 2789

  Fly  3313 ---ISE-PLRLNSFTVEPLNLLLSVHTSSRLYIALDHSPLSFSRYERQQILTVPLRFGQSLGLHY 3373
               |:| |:::||..::.:.:.|.        |.:||       .||                ||
Yeast  2790 LGNINEAPVKVNSLFMDNVRVPLP--------ILMDH-------IER----------------HY 2823

  Fly  3374 LSGAIFGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGLFRG--PWGFLVGVTQGSASLLR 3436
            .:..::....::||.:..|:|.||..:.|:|:.|....|.||....  |....:.:.:|..|..:
Yeast  2824 TTQFVYQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSFAK 2888

  Fly  3437 NVTAGTVNSVTKLAGSVARNLDRLTLDAEHIELTEARRRAR----------PQGFADGLTQGLTG 3491
            ....|..:|::|..||:|:.|. :|.|.|...:...::|..          .|.||..|..||:|
Yeast  2889 KTVFGLSDSMSKFTGSMAKGLS-VTQDLEFQRVRRLQQRINKNNRNALANSAQSFASTLGSGLSG 2952

  Fly  3492 LGISLLGAVGGLAHHTLEARSSVGVIAGLTKGIVGALTKPISGAAEMLALTGQGVLHTVGFNAM- 3555
            :.:.        .:..::...:.|.:.||.|||||..||...|..::.:...|||..|.....|
Yeast  2953 IALD--------PYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKSTTTVLDMQ 3009

  Fly  3556 -------PQQVE-PSFIRNVALHGSSNRIW-------SYLPEELSRDQMLFFSEIMLQISTQLRP 3605
                   |:.|: ...|:...|..:..:.|       .::.:|.....:|...|:.:.:|.|
Yeast  3010 KGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVILPGKELAVIVSMQ--- 3071

  Fly  3606 ALLFLTSSVLAIMQSDSEDLAFASPISKVD-VLADREDPSKLYLSLKSE 3653
                    .:|.:|..:::|.:::....:. :..:|   |.|.:.|||:
Yeast  3072 --------HIAEVQMATQELMWSTGYPSIQGITLER---SGLQIKLKSQ 3109

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13B	NP_651753.2	Chorein_N	5..117	CDD:289396	38/116 (33%)
		VPS13_C	3319..3468	CDD:293514	35/150 (23%)
		ATG_C	3473..3546	CDD:286423	20/82 (24%)
VPS13	NP_013060.1	MRS6	1..2294	CDD:227376	567/3215 (18%)
		MRS6	<2356..3144	CDD:227376	158/866 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344433
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5043
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16166
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960