Protein Alignment Vps13B and vps13d

DIOPT Version :9

• Sequence 1: NP_651753.2
• Gene: Vps13B / 43550
• FlyBaseID: FBgn0039727
• Length: 3731
• Species: Drosophila melanogaster
• Sequence 2: XP_001919988.5
• Gene: vps13d / 567879
• ZFINID: ZDB-GENE-050912-1
• Length: 4386
• Species: Danio rerio
• Alignment Length: 4970
• Identity: 856/4970 - (17%)
• Similarity: 1536/4970 - (30%)
• Gaps: 1953/4970 - (39%)

  Fly     4 LESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELS 68
            ||..:..:|.:|:.|||.|...:...::|.:|.|..:||.||.:.| ...:||.|:.:|.|.:::
Zfish     2 LEGLVAWVLNTYLGKYVSNLNTDQLSIALLKGAVELENLPLRKDAL-RGFDLPFEVKAGVIGKIT 65

  Fly    69 ILVPWTKLMSEPVKIVINTIEFV--AKLPDSESKQRRASFQREQRR------KSKRESVEQPDQT 125
            :.:|:.:..|:|..|.::.:..:  ..||....:.:....:|||::      :.|.:| |...:.
Zfish    66 LQIPFYRPHSDPWVICMSQLNLIIGPALPQEYDEVQEREAEREQKKQLLKALEDKWKS-ECEQKG 129

  Fly   126 KSPGPASSSSVVNKIINNINLQCHNIILKYVEDDI----------VVSMNVQTLNFSSAGEDWKP 180
            :|...:.::|||.:|:.||.|:...:.|:: |||.          |...||...|.|.     :|
Zfish   130 ESYWYSVTASVVTRIVENIELKIQGVHLRF-EDDFSNPEKPYAFGVCIKNVSAQNCSK-----EP 188

  Fly   181 TMVDIHPVSVVMRKLLQVSDLTICLDKRNT----------AGRIEVCQ---------EPVLYRCT 226
            ..      .::.:|.|::|:.::..|...|          ..|:..|.         |||   |
Zfish   189 AQ------KLIRQKELEISEFSVYWDTECTMLGDLPSSEIQERMSKCMQSREHQYIFEPV---C- 243

  Fly   227 LECRVLRKYNAN--TVSTTSTTRI--GVFTKSLDINVSSLQFPMVMRLVKML------------- 274
              ..||.:.||:  .:.:.:|.||  .|..:.|.:.:|.:|:..:|..:|.|
Zfish   244 --ASVLVRRNASKEPLRSRNTPRIEGQVQLEPLSLRLSQVQYQQIMAFLKELDRREKEMLFRKWR 306

  Fly   275 --------------------------------------------------------LELKPAEFE 283
                                                                    :.|.|.| |
Zfish   307 PKLTISGNCRQWWMFAINANLHEIRKQRRHGSWDFALHRARDAKLYTSLYVQRLKGVTLSPQE-E 370

  Fly   284 DDPQNPEDQEAVAE------------------------------------GSESQQGTESAG--- 309
            .:.:..||::.:.|                                    ||..:.|  |:|
Zfish   371 SEMERIEDEQTLEELQILRETVYVSFRKHEEIAESLREPLINESPATSPSGSIPKSG--SSGMIQ 433

  Fly   310 --RSVF--WWAW---------------SLLPS-------------FDTEAPSSSCDTPT--GHAF 340
              :|.|  |..|               .|||.             ||....|.:.:|.|  .|.|
Zfish   434 YLQSWFPGWGGWYGGTERGPDGQPVSDELLPGTAQWEILAETDDLFDPLEDSQTLNTFTRRDHLF 498

  Fly   341 ----------DLGVYAEELNFQLKNSEYFTDQSMGGIK-RIRYTP-----ILRISLGGLYYERTI 389
                      .:.:|.|..|..|.:..........|:| .:...|     :|.:.||||:
Zfish   499 ARLDFKLEKAAVTLYHENKNKPLLSESGVIQLEFSGVKIEVESLPRSESSLLTVKLGGLF----- 558

  Fly   390 LKECDWANVKAGLSSMCMEPLGAYRSDDLV-----DRNLVNTQEFQQERSFIDKSLFDENYMFAE 449
            |::   ...:..:..:.:.|    :.|.:|     .....|:.|:....|.::.|......|..|
Zfish   559 LRD---LTTQGSIFPVLVSP----KPDKVVVAINQPFGQTNSTEYSNPASDVESSAPPVFEMIYE 616

  Fly   450 RSWCSYNYADYVARNTDEYMLFRSPVLAFDVIEH----RVPKPSSHPVAESQLRDL-GVRIQYRL 509
            |:.....:...:..||....:..:|.....|.|.    ||........:|.:||.. ..|.||..
Zfish   617 RNPIRSKFERRLEVNTSPLNIIYNPQAIKKVAEFFYKGRVHTSGFGYQSELELRVAEAARRQYNK 681

  Fly   510 LSAGITFHFSQSFVQVKKVISDLIRPYDYPGYRSESMKDEDRGVPE---PENKNSE---MTIPDL 568
            |.       .|:..::::.|..|:........:..:|| .|...|:   |::..||   :.:.||
Zfish   682 LK-------MQTKAEIRQTIDQLLVGEFIENSKHWTMK-LDICAPQVIFPDDFQSEDPMLVVVDL 738

  Fly   569 EYLMGLVPTCNYKIELRNIVVQ-----------------LYPRQQQD--------ESSAINQHQL 608
            ..::......::|..|:....:                 ..|.|:.|        :.|::...:.
Zfish   739 GRILLTNSQEDHKTNLKTSQTEGESDEEFQTPLATPPASPPPEQEVDVKGQEKPRDFSSVKSSEG 803

  Fly   609 TTTVRQSL-----LPYLQLKISL---------VEGTMCGPVNPVRLVQLITHLEEK--------- 650
            ...:.::|     |.:..|:|.:         ::.:..||.:.|....::..||::
Zfish   804 AQIISRNLYEKYSLSFNDLQIMVGHYKDNWKHLQESDVGPTHVVEKFNVLLQLEQRLRYTSDPQF 868

  Fly   651 PRDVVNACYNCF--HFNVKNLALM------IMNTTPDNGRAKLLNIPRVQVNWNRLLAP------ 701
            |..|::......  |.|::.:..:      :.|:..|.|          ..|...|.:|
Zfish   869 PGAVLSGTLPDLKVHINLEKMTALRSCLARLGNSGADEG----------DNNGENLKSPDPLTLR 923

  Fly   702 --HLWRQNEA--PLETSE--IKSEIITLEFSKRELIIAKRLVPLISSFSGQDLCDLAHIVANVNV 760
              .::::.::  .|:.|:  :...::|||...||:::..:|                 ::...|:
Zfish   924 HEKIFQREDSDWKLQGSDKNLTKSVMTLEQHTREVLVESKL-----------------LLVEFNI 971

  Fly   761 NSDVIKLQS----------VGTKLNLVYHKYHTHLAAVGSLQGVH-TDAVHTKMNIRNVVLSTSK 814
            |...:.::|          .||..:.|...|...::.  ::.|:: .|.:.|..:..::::::.|
Zfish   972 NYMQLGIESGGRYISVLKVFGTNAHFVKRPYDAMVSL--TVHGLYLVDTLQTYGSDFDLLVASHK 1034

  Fly   815 NAD-----NKWLEMQCQFPLEEVHSEQEKIPGTVVCLWLEPFRITTDIYLLQFLNFSDNSGR-QI 873
            :..     ....|.|...|:...:...| :||.        .|.::|      |.|...|.| ..
Zfish  1035 HLSFDVPTGSLRESQPTSPVSPDNKSPE-LPGL--------HRNSSD------LVFDKASPRGSP 1084

  Fly   874 TKDKEVETDLESVNQSEPPITQSVSNYSTISASAIAFN---DFQPRRISRNNSRKISVPEETVHL 935
            .:|:|....||               |..||:...:.|   ..|...:..||...|..||..|.|
Zfish  1085 LRDQEALIKLE---------------YQFISSDCPSMNLDSSLQVTSMQVNNLDIILNPETMVEL 1134

  Fly   936 ------SSERDERHTQAEPLTIPVANKPQPSNFDTTDFV--KRLTKMVVLVEIAQAKIDVCEVMM 992
                  |..::|.....:...:|...:.: .|:.:| :|  |.||     |||.:..:    :::
Zfish  1135 LKFLQQSFPKEESSPTQQIAPLPNGEENE-ENYQST-YVQNKELT-----VEIHRLNL----LLL 1188

  Fly   993 RKTPGHTDVEYTSIRLPHMKVKSGNCEA--IQRGNIRGV-IPVASNTELLNWVFDLNEFNVCYRR 1054
            |.....|             |..|..:.  |...:|.|. :.|:..:.|     |:|....|.:.
Zfish  1189 RTVTTGT-------------VLGGEKKGMKIATASINGTKVNVSMGSRL-----DVNGSLGCIQL 1235

  Fly  1055 ANVTE----------------------MIIAPVR-TTITLALSFKTSDKVDGSKGKEDKCANTCS 1096
            .::|:                      :...|:. .|.:.||||:..:|..|.          ||
Zfish  1236 VDLTQEGGRSQFVVSIGSVEDSTATDGVAFFPIAGMTPSEALSFRFMEKSQGE----------CS 1290

  Fly  1097 INVHVDMSAINIFAQRVKLLHEHCLIISKMYGSLCPDEPASKW----QTGKMKPRLEVYTGSAQN 1157
            :.:.:.....|..|:.:|.|            ||..:|....:    :|...|....:.|.:|
Zfish  1291 LQLQMASLHYNHSAKFLKEL------------SLSANEVEDNFRFMLKTAATKVSTVLVTKTA-- 1341

  Fly  1158 YPVIKEFLELDPNFEAPKVKSAPKSSVILFCQWTIPRISFEMENSNDF----KHSKIVMSLEDLL 1218
                 |:..:...|:.|..:|..:|.    |.||:.  .||   .:||    |...:...|..|.
Zfish  1342 -----EYSGMVSLFDNPSRRSRRQSQ----CNWTLD--PFE---EDDFCDPEKEPALDSFLVKLT 1392

  Fly  1219 LNIDKHSDFNKITTK---------------IENFGLNYYEEKHEEWEKIDDLHIKMLGDSTNLPL 1268
            |::...|....|..|               |:||......|:.:...::.|:.
Zfish  1393 LDVSIESPVVSIPRKPGHPELLVGHLGSIQIQNFVTGQDSEREKLQVEVKDIR------------ 1445

  Fly  1269 ISVVITTVSLEDLYAKIGAR--------------------NPHNKQHTISEVL------------ 1301
                :.:|:..:|:.|.|||                    .|...:|...|.:
Zfish  1446 ----LYSVNTSNLFLKKGARLNSSTTSGPSPSHGGNISLNEPQFTRHDFFEYISRGKAFHILKDA 1506

  Fly  1302 -----IEVQPIE-----MVLNLD---QITEFM---------VPIC-------EVLEIIGNSASAQ 1337
                 :|..|::     ..|:.|   |.|..:         |.:|       :||:.:.|.:..:
Zfish  1507 TIQLTVEKVPVDENSTFTFLSCDEPYQSTGILRVEGKFVNAVEVCLCKPVYEQVLQTLDNLSFTE 1571

  Fly  1338 S-----ANKPSAPVPSKITT-------------VQDLPMVHLN----SKGIYVYLPL-------- 1372
            .     :..|:.|.|:..:|             .:|.|...::    |..:...|||
Zfish  1572 DQRVTPSQPPTPPPPTPSSTKPHRFPDHQGGLFARDPPHGGVSYSTLSSSLSATLPLHNESPPLQ 1636

  Fly  1373 ----------------------STGKKSCSVLLLRIE------------SIQLTPSLENPLVRQL 1403
                                  ...:.|..::.||.:            ||.:..:|.:.|:..|
Zfish  1637 PPSFTQVRATFRVSELQVQLSGDLSQGSQGLVSLRFQDLEGDFTKDHPHSISIQLALHSLLMEDL 1701

  Fly  1404 VRPDIYQKAAEL--------------------------NMLST--PGAL---VEDRQ--YELSVR 1435
            :.|:...|...|                          |:|.|  |.:|   .|:.|  ::...|
Zfish  1702 LEPNPESKYKHLMVSRGAPKPSTFSPKEYLSQSCPTASNVLYTEMPRSLPAQFEEAQNVFQFYQR 1766

  Fly  1436 RVSLSTGNWKQTQEYRIEKTLASKHDN--PAFEWNNQSQSTELDHMEIFKDFDFIMIYAPAISYD 1498
            ..|..:.:.::           ||.|.  |:....:.|:.|...|..  .|||..:::...:..|
Zfish  1767 HPSTPSASSRK-----------SKKDAECPSTPPPSPSRQTPSPHPR--PDFDDSLVHINVLMVD 1818

  Fly  1499 --------RFLVCGQS--VEYNCATDFVASLNTHQISLISCIIVRAQRLGCIIDQVCVK--NAEL 1551
                    |:...|:|  |::|| .|.:.:|.|.      .:|:....:|...:...||  ...|
Zfish  1819 RRHPEFKTRYGSIGRSVDVDFNC-LDILITLQTW------VMILDFFGIGSTANNHAVKVPTTTL 1876

  Fly  1552 PKARSH----KTLGNISK-YNSVDNSIYFPADPKVFKKDTWIPKSSKKLVSERLSYTNASTSFTD 1611
            .....|    .||.::|. |..::..:....|.||......:.|.:.:|
Zfish  1877 QPMHEHSPENSTLNDLSDLYPEIEEGVNTKLDLKVHSLSLVLRKKTNEL---------------- 1925

  Fly  1612 AKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLAAEEINRSG---RQPFVLSYPSSVSFVAGIFVLK 1673
            ||.|....:...:...|   ...::|...||:..::...|   |:.|......::
Zfish  1926 AKASVSKLFTHMEMIDG---DLALQGSLGSLSLSDLTPHGDLYRERFTTRGGEAL---------- 1977

  Fly  1674 IYDVLELEE----LERPV-MKPLFLMTVSQPSFMSTQNFKAAVTQ-----ASIFNVNISVAKADV 1728
            :|::.:..|    |:|.. ||....|...|  ::.||.|:|.|..     ..:.:| :...:|.|
Zfish  1978 VYNIYKYGETDFFLQREYDMKVSLQMASVQ--YVHTQRFQAEVVAFIQHFTQLQDV-LGRQRAAV 2039

  Fly  1729 DGKVDSERFNESVFATLPGQLGSSGIPPPLLTIKTQYDRLHQKEVDVELRKPILLRIC------- 1786
            :|:...||...:....|..:.|:     |:|.|.   :....|.:.|.....:.:|.|
Zfish  2040 EGQAVRERPQRAARVLLDIEAGA-----PVLLIP---ESSRSKRLIVANLGQLRVRNCFLPAGAR 2096

  Fly  1787 -------ENTIKQL--ASDVFRIY----TVLHETPCFNVRSPRP----VPEGS------------ 1822
                   ::.:|.:  .||..:..    |....:..|.:..|:|    :|||.
Zfish  2097 GTFSLRDKDRVKDVHFTSDAGKTSQKRPTSFSSSSGFVLGKPQPSLGCIPEGDVLGLEDHVCLLD 2161

  Fly  1823 --QLRQLKMNCYNADRF----------HLSCDRITAKF-----------------------YDEE 1852
              .|...:|:.:.|:|.          ||..|.:...:                       .|:|
Zfish  2162 CIALDLQEMDIFAAERLPCEPWDSAGKHLETDLVFPSYSVRRSGESLLKERCHLKLKVERNLDKE 2226

  Fly  1853 RSYKCSFVWLDVSTRIKFSS--------RPQ--KAVIRSNIG----------------SFYVQSG 1891
            .|:...    |:|.....||        |.|  :.::..|:|                |:.|.||
Zfish  2227 LSHAVP----DMSIHGSLSSVHCSLDLKRYQMIRGLLEHNLGEPVEEFLRPYNLQDPSSYTVLSG 2287

  Fly  1892 EKMLLHPLLMRL----------------------------------------SVDLVSEPWSEEL 1916
            :......||:.:                                        ||:||    |..|
Zfish  2288 DVFTSLSLLVDMKDVSLELLDNHKSTGHNCSLARFDFMKSKLLFESFSNGSKSVNLV----SHSL 2348

  Fly  1917 LVNAT---------------------------------LKLNYLHI-DAGVFSILQLQKAQQGVN 1947
            |.:.|                                 |:|:|... |:..|:::        :|
Zfish  2349 LAHDTRLTGSSAPTEGKHNVFDCILQPSRTGTNRASLQLELHYRSTRDSSCFTVV--------LN 2405

  Fly  1948 RIREYADREW----QQFLRSRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRA 2008
            .:|.:...:|    |.||......||            .|:|:     :.|..|:     |....
Zfish  2406 NLRVFLIFDWLQLVQDFLHMPVEKGT------------APTHQ-----RWPSGSS-----DQGCT 2448

  Fly  2009 GAFQFVYLNSESVLPMPYQVQIIKKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRM--- 2070
            ||          |:|...:..::.|.                   ..||:...:.:.::..:
Zfish  2449 GA----------VMPKTVKSGVVTKR-------------------STVPVTQDKQLEVKINVTGT 2484

  Fly  2071 EYFSETHETFLHYCDFMLSETSTKQLTPP--DRPICATIWRVVILQSLISVDGTCFEGSEDED-L 2132
            |:......:.|.....:|..|:.....|.  |||...::..:.:.        :|..|||.|. |
Zfish  2485 EFVVVEDSSCLDTNAIILKGTTVLTYKPRLLDRPFSGSLAGIEVF--------SCRLGSEQETAL 2541

  Fly  2133 SI--------------EYLQSDFKVDENN--DFILHPKVLVGCMRIDTVFRAEKVPKLQLLLCCQ 2181
            ||              .|..|...:|..|  ||   |.:|           ..:.|.|.:.|...
Zfish  2542 SIIDPVNVQMELCGSPTYQSSSGLLDAFNIEDF---PPLL-----------EIQFPALDIRLSYN 2592

  Fly  2182 DIELNF-----------VNQTDNTGELPKQLNKYRLRQTPNITQTFLTVHVEDLQMHSRIYSRND 2235
            |::|..           .|.:|...:.....:. ....||:.|                   ::.
Zfish  2593 DVQLFLAIAKSIPTAASANPSDTAVDAESSAST-ASTDTPSKT-------------------KDS 2637

  Fly  2236 FSLQTEMRAR---VKCLDYGFLNMLDVLEPMKFSSYVRLTDYPRSLVQANFLVDKLRLNCGPHVI 2297
            |..:||....   .:..|.||                |..|..|:|:.....:|:
Zfish  2638 FRQKTEALLEGQLTRLQDLGF----------------RKEDCRRALIHCRGQLDQ---------- 2676

  Fly  2298 HTLLSSKYHWQEVLQQKDVRHVLMPKLVIVNRIQTPISFGQTNTVEKIPVNPGEVQLYHFRSCSH 2362
                ::.:.|:......                      |::.|      |.|        |.||
Zfish  2677 ----AATWLWENAESMS----------------------GRSRT------NSG--------SSSH 2701

  Fly  2363 VQELTFFITNPKTLLVDSSDSVHIALKFEDEEKIHNLRVGEYCI--TLKLAKLSTTQIYILVK-G 2424
                   ...|.:.:...::||.|.  |.|:           |:  .:.||:::.:::|:|.: |
Zfish  2702 -------SAPPLSGVEVKAESVCIC--FIDD-----------CLDCDVPLAEITFSRLYVLQRIG 2746

  Fly  2425 QIELVSMVPFNLVTEFREEEIN-YDESTPPEHLLLSKERSSYYQ----------NVKRNADINMR 2478
            .:: .....|.|..::...|:: ::....|....|..:|.:..:          ..|:..|:|:.
Zfish  2747 SMQ-EGKASFTLSGDYYNRELSGWEPFIEPWPCFLDWQRQAAGRLHPPRLKIGVRAKQRLDVNIT 2810

  Fly  2479 LKL-------------------------TAGLG-RGRTGDIPLKTNNNLPWLVKVPTQSAQQFIS 2517
            ..|                         :|.|. .|.:.| |.....:|| |..:.|:|:.....
Zfish  2811 SVLLEQYSTTKTSWLADYCKEDEQSPQPSAALSWMGSSVD-PPSFGQSLP-LAYLRTRSSTSLTC 2873

  Fly  2518 IWVRI-LREDIKMDKPAEDFQPQKILICIWPIFEICNMLSCAV-KATESTT------GESSTIEA 2574
            :..:| .|.|:|:.|..:.|.|          :.:.|...|.: .||.:||      ..||:.::
Zfish  2874 LEQQIHARADMKLSKRRQPFVP----------YALRNHTGCTMWFATLTTTPTRVALSHSSSADS 2928

  Fly  2575 MGGRWALNTATTHATE--------HNIGFTFSG--ILRGSSKDE---YSLMLRTMDWHK------ 2620
            :.......|..||...        ..|.|.|..  .||.....|   :.|::|.:.|.:
Zfish  2929 ISEVHGPGTDDTHNISQWREVLPGEEIPFEFEAREKLRHRHTHELKLHQLLVRVVGWEQVKPVSV 2993

  Fly  2621 -----FFYY----------------------DPTVW-------------TIENALHKLGKSSKRK 2645
                 ||.|                      .|.|:             |:|.:..|:
Zfish  2994 DKVGVFFRYAAPDRNNPSSTVGSPISRTNIIHPHVYFSALPPVRVVFSITMEGSARKV------- 3051

  Fly  2646 WPLNDPEELRVSRVLDFENAFDVKYQTKATREF---------------SCCQGLDVTAWGMFING 2695
                    :.|...|..:|..:|..:.:.....               :....|.:|:|.:....
Zfish  3052 --------ITVQSALTVKNRLEVPMEVRLDSPSAPDKPVVLPPILPGEALAIPLHLTSWRLQARP 3108

  Fly  2696 TGLYVAIFMIQEQARLDLKANSLQMMPKLKSA----FTIDVRFDNGWKSSTPICL----EDFTQ- 2751
            .||  .:|.    .::.:...|::...::.|:    .:.|  ||...|.|...|:    |::.:
Zfish  3109 KGL--GLFF----CKVPIHWTSVERPGEVSSSKRECQSAD--FDEQLKRSFRFCVVIKKENYPEQ 3165

  Fly  2752 ---KSSSNAGRSLYLRYNSFVDIVIVERDEVLRLILEYRQEDDGRRLFKLRSKFVFTNFTDVVLN 2813
               |:.:..|....                       |||  .|..:|.|.: .|..|.....||
Zfish  3166 QPAKTVAGGGTKQI-----------------------YRQ--PGHTIFLLPT-LVLANLLPCDLN 3204

  Fly  2814 -----------------ALTLAMDHKENSTREEV----EAYSICKKARSLVSSESTKNCSGNAMD 2857
                             |:..|.|..:|.   |:    |.:.:||:   |:....|:|......
Zfish  3205 YYIKGTSIKGTMKPGKEAVLHAADTSQNI---EIGVLLENFPVCKE---LLIPPGTQNYVVRMR- 3262

  Fly  2858 VFYDLNAHKAKHNCDTAFVYFVCFSV------GGSREISIPIP------LAVPFTRR-------- 2902
             .||:|..            .:|.::      .|:.:|.|..|      ..:|...|
Zfish  3263 -LYDVNKR------------LLCLTIRIILRAQGALKILISAPYWLANKTGLPLIFRQDNGKTDA 3314

  Fly  2903 ------------------CF---------SLQAG----PESIP--------------LMITLIEK 2922
                              |:         :::.|    |:.:|              ..:.:|:.
Zfish  3315 AGQFEEHELARSLSPLLFCYTDKEQPNMCTMRIGKGIHPDGVPGWCQGFSLDGGSGVRAVKVIQH 3379

  Fly  2923 DN----VHYLNV--------FRDT-----APAIVISNNTNVKFIVAQ--------TSASENSNVS 2962
            .|    ::.:.:        :|||     ||..::.|.::.|...:|        |:..|....:
Zfish  3380 GNRPGLIYNIGINVRKGKGRYRDTHIVTFAPRYLLDNRSSHKLAFSQREFARGKGTANPEGYIST 3444

  Fly  2963 CTNSEFVGRNFEW-----NQL----VLPHSNCYYT-------PPQMYANFPDV----EFTMCNLS 3007
            ...|..|   |.|     :||    ::...||.::       |...:.|..|.    .|....::
Zfish  3445 LPGSSVV---FHWPRNDYDQLLCVRLMDVPNCTWSGGFEVNKPKSFHINMRDTLGNCFFLRAEIA 3506

  Fly  3008 LAVYKDKLCAKNKIAWS------KPIRTD-------KSWQKFLHVPHHG--DVKV---------- 3047
            |.      .|.::|::|      .|.|.|       :.||       ||  |:::
Zfish  3507 LK------GATHQISFSDTDQLPPPFRIDNISEVPIQFWQ-------HGVADIRLHTEVKPGADL 3558

  Fly  3048 -VVCDK-----------------------------HRAIRLNIYYIAQQLEFS------------ 3070
             ..||:                             ::....|..|||....||
Zfish  3559 DYACDEPILEPYLTVTVKGAGSSEVTADMNFFREYNKLYYENFIYIAASFTFSEDGGKRPVGKNR 3623

  Fly  3071 -------VKDLRSRLTKPENVLM---------------------------PSQEQAAPRP----- 3096
                   |.|:.   ||.:.|::                           |..:.:.|||
Zfish  3624 AVSCAELVLDVE---TKTQRVILKKKEPGKRSQLWRMTGSGMLCHEGSSPPQSKPSQPRPLSSSL 3685

  Fly  3097 -----------DESSE----QENDTKRVTLPNMVTCAHFNEECESKTQTRIKIFIKSFVFSLQTD 3146
                       |.|.|    :..|::|.|....    |||....:....|:.:.:...|..|...
Zfish  3686 VLDIAGLAAVTDNSYEPLMLRRPDSRRSTTQTW----HFNSGMLTCGLPRLVVQVSGGVSGLYDG 3746

  Fly  3147 --------------NRENDFVKTEV--------CNIYADDSMLIYD----------------DDD 3173
                          ..|..|:..::        ..:..|....:..                ::|
Zfish  3747 AEVVLGPDSGILEATPEQQFINQKMRPGSGVLSVQVLPDGPTRVLQISDFNQRRVNRPSPSTEED 3811

  Fly  3174 DQRE-----------------------------------------------------LRLQLPNL 3185
            ..:|                                                     |.|.:.|:
Zfish  3812 PNKEIAQTKFPEEELEVVVNLEEGVGLSLVNKLPEELVFATLSGIDVHFTRTAANQVLELTVKNI 3876

  Fly  3186 QVDNQLYSSGKYDFPVLLCAEKLYRRNCSLPQVYDLDHVYKQQAQRTPVSL-FTFIFYQDEMQLQ 3249
            ||||||..:   ..|||||.......:.:|    |.....:..|.:.|..| .|.:|       :
Zfish  3877 QVDNQLLGT---THPVLLCVTPGSSESTAL----DSGPALQVNAVKVPSRLMLTDLF-------K 3927

  Fly  3250 NVRCQIPPFRVYIEDAYLNQLL--------EALVECEPSNCVYSPPVEQDQILLPAGMTLLPDQV 3306
            ::......:.|.||:..|.:||        |..:|....| :|....|.     |.    .|.:.
Zfish  3928 HLMVTARRYTVIIEEKLLMKLLIFFGYGQTEGEMEKLDEN-IYEKASED-----PG----TPKRY 3982

  Fly  3307 VAQSLYISEP-LRLNSFTVEPL-------------------NLLLSVHTSSRLYIALDHSPLSFS 3351
            ..::|.||.| ::|:.||...|                   :.:::::..:|::
Zfish  3983 YFENLKISLPQVKLSVFTSHKLPHDLKALKGTLGFPLIRFEDAIINMYPYTRVH----------- 4036

  Fly  3352 RYERQQILTVPLRFGQSLGLHYLSGAIFGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGL 3416
            .||.|:::.      ..:..|:....|..|..::||::.||:|.||....:.|:.:.:.
Zfish  4037 PYETQEMVI------NDILKHFKEELISQAAQILGSVDFLGNPMGLLNDVTEGMNELIK------ 4089

  Fly  3417 FRGPWGFLVGVTQGSASLLRNVTAGTVNSVTKLAGSVARNLDRLTLDAEHIELTEARRRARPQGF 3481
                :|.:.|       |:|:||.|..||..|.||:::..|.: |:|..|  .|| |...|..|.
Zfish  4090 ----YGNVGG-------LIRSVTHGVSNSAAKFAGTLSDGLGK-TMDNRH--QTE-RECIRYHGA 4139

  Fly  3482 ADG--LTQGLTGLGISLLGAVGGLAHHTLEARSSVGVI----AGLTKGIVGALTKPISGAAEMLA 3540
            ..|  |..|:.||...::|.:..:...|:|...:.|.:    :||.||:||.:|||::||.:..:
Zfish  4140 TSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFFSGLGKGLVGTVTKPVAGALDFAS 4204

  Fly  3541 LTGQGVLHTVGFNAM--------------PQQVEPSFIRNVALHGSSNRIWSYLPEELSRDQMLF 3591
            .|.|.|......|..              ||.:.|.|        ||
Zfish  4205 ETAQTVRDMASVNNRLSVQRVRKPRCCKGPQGLLPRF--------SS------------------ 4243

  Fly  3592 FSEIMLQISTQLRPALLFLTSSV-----LAIMQSDSEDLAFASPI---SKVDVLADRE------- 3641
                 ||...|  ..|..||.::     :|:...|:..:..:|.:   .|....||||
Zfish  4244 -----LQADGQ--EQLFHLTDNIHSEYFIAVEPIDTYCVLISSKVVYFLKPGEFADREAIFLEVK 4301

  Fly  3642 -----------DPSKLYLSLKSERRDDFEG 3660
                       |..|:|:.|..:......|
Zfish  4302 YDDLYHCLVSKDHGKVYVQLTKKAESTSSG 4331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13B	NP_651753.2	Chorein_N	5..117	CDD:289396	30/119 (25%)
		VPS13_C	3319..3468	CDD:293514	35/167 (21%)
		ATG_C	3473..3546	CDD:286423	25/78 (32%)
vps13d	XP_001919988.5	Chorein_N	3..112	CDD:315323	29/109 (27%)
		VPS13	139..358	CDD:318996	42/236 (18%)
		VPS13_mid_rpt	615..889	CDD:318998	47/281 (17%)
		UBA_VP13D	2650..2685	CDD:270491	9/64 (14%)
		SHR-BD	3285..3568	CDD:310922	47/298 (16%)
		VPS13	<3762..4287	CDD:330393	122/619 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5043
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930