Protein Alignment Vps13B and Vps13a

DIOPT Version :9

• Sequence 1: NP_651753.2
• Gene: Vps13B / 43550
• FlyBaseID: FBgn0039727
• Length: 3731
• Species: Drosophila melanogaster
• Sequence 2: NP_766616.2
• Gene: Vps13a / 271564
• MGIID: 2444304
• Length: 3166
• Species: Mus musculus
• Alignment Length: 4045
• Identity: 710/4045 - (17%)
• Similarity: 1320/4045 - (32%)
• Gaps: 1396/4045 - (34%)

  Fly     5 ESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELSI 69
            ||.:..:|..::..||.|..:....:.:|:|.|..:||.::...| .||::|.::..|||..|.:
Mouse     4 ESVVVEVLNRFLGDYVVNLDESQLSLGIWKGAVALKNLVIKENAL-HELDVPFKVKVGHIGSLKL 67

  Fly    70 LVPWTKLMSEPVKIVINTIEFVAKLPDS--------ESKQRRASFQREQRR----KSKRESVEQP 122
            .:||..|.::||:.|:..| |:..:|.|        |.||...:.|:|.:|    |.|....|:|
Mouse    68 KIPWKNLYTQPVEAVLEEI-FLLIVPSSRIQYDPIKEEKQLMETKQQELKRIEKAKQKVFDKEKP 131

  Fly   123 DQTKSPGPASSSSVVNKIINNINLQCHNIILKYVEDDIV-------VSMNVQTLNFSSAGEDWKP 180
            .:.|.  ...:..:|.:||.|:.:|..:|.::| ||||.       ..:::|.::..:..:.|.|
Mouse   132 REEKQ--DTFTEKLVTQIIQNLQVQISSIHIRY-EDDITNGDKPLSFGISLQNISLQTTDQYWIP 193

  Fly   181 TMVDIHPVSVVMRKLLQVSDLTICLDKRNTAGRIEVCQEPVLYRCTLECRVLRKYNANTVSTTST 245
            .:.|  ....::|||:::.:|.                  ..:....|...|..|:    .:...
Mouse   194 CLHD--NTEKLVRKLIRLDNLF------------------AYWNVNSEMFYLNDYD----ESLKA 234

  Fly   246 TRIGVFTKSLDINVSSLQFPMVMRLVKMLLELKPAEFED-DPQNPEDQEAVAEGSESQQGTESAG 309
            .:.|:..:    |:....:..|.|.:....:|:.....| |..:|:...||
Mouse   235 LKNGIVNE----NIVPEGYDFVFRPISASAKLQMNRRSDFDFSDPKINLAV-------------- 281

  Fly   310 RSVFWWAWSLLPSFDTEAPSSSCDTPTGHAFDLGVYAEELNFQLKNSEYFTDQSMGGIKRIRYTP 374
                          |....:...:.|  ..|.|....|.::...:|..|           .::.|
Mouse   282 --------------DLHTIAIEFNKP--QYFSLMELLESIDMMTQNQPY-----------RKFKP 319

  Fly   375 ILRISLGG----LYYERTILKECDWANVKAGLSSMCMEPLGAYRSDDLVDRNLVNTQEFQQERSF 435
            .:.:.|..    .|...:||:    .||...|.....|.:..:|            .:.::.|.|
Mouse   320 SVPLHLHAKEWWAYAIHSILE----VNVCPSLRMWSWEHIRNHR------------YKMKRYREF 368

  Fly   436 IDKSLFDENYMFAERSWCSYNYADYVARNTDEYMLFRSPVLAFDVIEHRVPKPSSHPVAESQLRD 500
            ..|.|..:                                           |||  |.....|.:
Mouse   369 YKKKLTSK-------------------------------------------KPS--PEILMSLEE 388

  Fly   501 LGVRIQYRLLSAGITFHFSQSFVQVKKVISDLIRPYDYPGYRSESMKDEDRGVPEPENKNSEMTI 565
            |    :..|....||....|:.|:.||.           ||     |....||.:||
Mouse   389 L----EKTLDVFNITIARQQAEVEAKKA-----------GY-----KIYKEGVKDPE-------- 425

  Fly   566 PDLEYLMGLVPTCNYKIELRNIVVQLYPRQQQDESSAINQHQLTTTVRQSLLPYLQLKISLVEGT 630
             |.....|.:.|.:          :....||||....|.:..||...:..|...:....:.|:.|
Mouse   426 -DNAGWFGWLWTWS----------ESNANQQQDVKPGILEEMLTPEEKSLLYEAIGYSETAVDPT 479

  Fly   631 MCGPVNPVRLVQLITHLEEKPRDVVNACYNCFHFNVKNLALMIMNTTPDNGRAKLLNIPRVQVNW 695
            :......::                      |..::|::::::
Mouse   480 LPKTFEALK----------------------FFVHLKSMSIVL---------------------- 500

  Fly   696 NRLLAPHLWRQNEAPLETSEIKSEIITLEFSKRELIIAKRLVPLISSFSGQDLCD---LAHIVAN 757
                     |:|....|...:..|.::....:|....|.:....|.||....|.|   ..|::::
Mouse   501 ---------RENHQKPELLNVVVEGLSTSVVQRPGAQAIKFETKIDSFHITGLPDDFKKPHLLSS 556

  Fly   758 VNVNSDVIKLQSVGTKLNLVYHKYHTHLAAVGSLQGVHTDAVHTKMNIRNVVLSTSKNADNKWLE 822
            ::   |...||                                         ::...|..|:.:.
Mouse   557 LD---DTSLLQ-----------------------------------------ITFEINPLNETVA 577

  Fly   823 MQCQF---PLEEVHSEQEKIPGTVVCLWLEPFRITTDIYLLQFLNFSDNSGRQITKDKE----VE 880
            .:|..   |||.::..:     ||..: :|.||...|::|.|..:.:      :||.:|    ..
Mouse   578 QRCTIEAEPLEIIYDAR-----TVNSI-VEFFRPPKDVHLAQLTSVT------LTKLEEFRAKTA 630

  Fly   881 TDLESVNQSEPPITQSVSNYSTISASAIAFNDFQPRRISRNNSRKISVPEETVHLSSERDERHTQ 945
            |.|..|.:::..:...::    :.||.:..
Mouse   631 TGLLYVIETQKVLDLRIN----VKASYVIV----------------------------------- 656

  Fly   946 AEPLTIPVANKPQPSNFDTTDFVKRLTKMVVLVEIAQAKI---------DV------CEVMMRKT 995
                       ||..||..       |..::|:::...|:         ||      .|.:|.:.
Mouse   657 -----------PQYGNFSP-------TSNLLLLDLGHLKVSSKRRSLLPDVRPSEASLEDIMHRA 703

  Fly   996 PGHTDVEYTSIRLPHMKVKSGNCEAIQRGNIRGVIPVASNTELLNWVFDLNEFNVCYRRANV-TE 1059
            ....|::.|||:|.:.:|.....||                                |:.|| |:
Mouse   704 YDSFDIQLTSIQLLYSRVGDNWKEA--------------------------------RKLNVSTQ 736

  Fly  1060 MIIAPVRTTITLALSFKTSD------KVDGSKGKEDKCANTCSINVHVDMSAINIFAQRVKLLHE 1118
            .|:.|:...:.|:.:....|      |:.|.                :.:.::.|..::::.:.|
Mouse   737 HILIPMHVNVELSKAMVFMDIKMPKFKISGK----------------LPLVSLRISDKKLQGIME 785

  Fly  1119 HCLIISKMYGSLCPDE-------PASKWQ-----------TGKMKPRLEVYTGSAQNYPVIKEFL 1165
                   :.||:...|       ||..:|           :.|:.|.||        .||.::..
Mouse   786 -------LLGSIPKPEPVTDVSAPARSFQIQASALPVSHISQKLIPLLE--------QPVTEDDS 835

  Fly  1166 ELDPNFEAPKVKSAPKSSVILFCQWTIPRISFEMENSNDFKHSK--IVMSLEDLLLNIDKHSDFN 1228
            | :..|:||       .|.:..|    |::|...:.:...|..|  .||:|..|.:..:
Mouse   836 E-EEFFDAP-------CSPLEEC----PQVSCRDKCTRQKKLQKKDCVMNLIQLRMRFE------ 882

  Fly  1229 KITTKIENFGLNYYEEKHEEWEKIDDLHIKMLGDSTNLPLISV---------------VITTVSL 1278
                 :....:.:|.               ::|| ..||::.:               :..:..|
Mouse   883 -----VAEVSIQFYH---------------LVGD-CELPVLEMGALGLGTEAEFRTFDLKGSAFL 926

  Fly  1279 EDLYAKIGARNPHNKQHTISEVLIEVQPIEMVLNLDQITEFMVPICEVLEIIGNSASAQSANKPS 1343
            ::|:.|.......||           :|:.::..||...|.::    .||.:....:|.:.|
Mouse   927 KELWLKCPEYLDENK-----------KPVYLITTLDNTMEDLL----TLEFMKVEKNAPNLN--- 973

  Fly  1344 APVPSKITTVQDLPMVHLNSKGIYVYLPLSTGKKSCSVLLLRIESIQLTPSLENPLVRQLVRPDI 1408
                |....|..|..|:.:|..|:                |..|::..|.:..|.::     |::
Mouse   974 ----STYNNVLQLIKVNFSSLDIH----------------LHTEALLNTMNYLNNIL-----PEL 1013

  Fly  1409 YQKAAELNMLSTPGALVEDRQYELSVRRVSLSTGNWKQTQEYRIEKTLASKHDNPAFEWNNQSQS 1473
            .:|:|     |...|..||:             |:        |.|.||.|  .|..|
Mouse  1014 REKSA-----SVSAAEPEDK-------------GD--------IIKKLALK--LPTNE------- 1043

  Fly  1474 TELDHMEIFKDFDFIMIYAPAISYDRFLVCGQSVEYNCATDFVASLNTHQISLISCIIVRAQRLG 1538
             ::..:::..:...:.|:.            |..:.|.:...:..|::..|            :.
Mouse  1044 -DIITLQLLAELSCLQIFI------------QDQKQNISEIKIEGLDSEMI------------MK 1083

  Fly  1539 CIIDQVCVKNAELPKARSHKTLGNISKYNSVDNSIYFPADPKVFKKDTWIPKSSKKLVS-ERLSY 1602
            .::.::..|            |.||...:|...:||        ||..:|  :.|::.| :.:||
Mouse  1084 PLVTEINAK------------LRNIIVLDSDKMAIY--------KKALYI--TGKEVFSFKMISY 1126

  Fly  1603 TNAST--SFTDAKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLAAEEINRSGRQPFVLSYPSSVSF 1665
            .:|:.  ::||..          ..|..:||                              :|..
Mouse  1127 MDATAGYAYTDMS----------VVDIRVHL------------------------------TVGC 1151

  Fly  1666 VAGIFVLK-IYDVLELEELERPVMKPLFLMTVSQPSFMSTQNFKAAVTQASIFNVNISVAKADV- 1728
            :..:|:.| :|.:|...:..:.|...|...|| |.:.|:....|....::|.|.::::: ||.|
Mouse  1152 IEVVFITKFLYSILAFIDNFQAVKDALAEATV-QAAEMAADGVKELARKSSRFALDVNI-KAPVV 1214

  Fly  1729 ---DGKVDSERF--------NESVFATLPGQLGSSGIPP--PLLTIKTQYDRLHQ--------KE 1772
               ...|....|        .:::|.|:...  .|.|||  .|:|||....||::        :|
Mouse  1215 LIPQSPVSQNVFVADFGLITMKNIFVTVTET--QSNIPPVIDLITIKLSKMRLYRSQFRNDTYQE 1277

  Fly  1773 VDVELRKPILLRICENTIKQLASDVFRIYTVLHETPCFNVRSPRPVPEGSQLRQLKMNCYNADRF 1837
            | ::|..|:.|.:...  :.|:.:.::      |.||||::        :||:.::        |
Mouse  1278 V-LDLLLPLNLEVIVE--RNLSWEWYK------EVPCFNIK--------AQLKPME--------F 1317

  Fly  1838 HLSCDRITAKFYDEERSYKCSFVWLDVSTRIKFSSRPQKAVIRSNIGS------FYVQSGEKMLL 1896
            .||.:.:|..|.....:     :|.........|:......:.|.:.|      ..|.:...:.:
Mouse  1318 ILSQEDLTTVFQTLHGN-----IWYGQDLSAPSSANKDPETMTSGVTSPPDHSPATVVTAAVVEV 1377

  Fly  1897 HPLLMRLSVDLVSEPWSEELLVNATLKLNYLHIDAGVFSILQLQKAQQGVNRIREYADREWQQFL 1961
            ||           :......::|.:.:.:||     ..::......:.....:|:
Mouse  1378 HP-----------QASQAHTMLNVSFQTDYL-----TMALYSPGPDEASFTDVRD---------- 1416

  Fly  1962 RSRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRAGAFQFVYLN-------SE 2019
                                 ||.|..|.....:.|:.:.|.||  :..|.|...|       |.
Mouse  1417 ---------------------PSLELAEFKLENIISSLKIYTDD--STVFSFSVKNCILDDKRSH 1458

  Fly  2020 SVLPMPYQVQII----KKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRMEY-FSETHET 2079
            .:...|..:.:.    ||:...|.:|        .|..:.|...|.:.:::...:|: .:..|..
Mouse  1459 VMKATPRMIGLTVGFDKKDMVDIKYR--------KIKTFVVTDAVVQEMYVCASVEFLMTVAHIF 1515

  Fly  2080 FLHYCDFMLSETSTKQLTPPDRPICATIWRVVILQSLISVDGTCFEGSEDEDLSIEYLQSDFKVD 2144
            |..|......|||.:..|..:.|                                   ..:....
Mouse  1516 FDAYMTSTALETSVQTRTTREAP-----------------------------------AQELGKW 1545

  Fly  2145 ENNDFILHPKVLVGCMRIDTVFRAE----KVPKL----QLLLCCQDIELNFVNQTDNTGELPKQL 2201
            |.|..|.:|::         ||.|:    ..|.|    |..:||:.      ..|.||
Mouse  1546 EMNILIKNPEI---------VFVADMTRNDAPALVITTQCEICCKG------EPTSNT------- 1588

  Fly  2202 NKYRLRQTPNITQTFLTVHVEDLQMHSRIYSRNDFSLQTEMRARVKCLDYGFLNMLDVLEPMKFS 2266
                           :|..::|||:.:..:      |..:.:.:|          ..||:|...
Mouse  1589 ---------------VTAAIKDLQVRACPF------LPVKRKGKV----------TTVLQPCDL- 1621

  Fly  2267 SYVRLTDYPRSLVQANFLVDKLRLNCGPHVIHTLL---SSKYHWQEVL------------QQKDV 2316
             :.:.|...|.....:..|..|.|...|.:|:|::   |:.|..:|.:            .:||.
Mouse  1622 -FYQATQLGRDPQMIDISVKSLTLKVSPVIINTIITITSALYTTKETVPEENTSNIAHLWDKKDT 1685

  Fly  2317 RHVLM---------PKLVIVNRIQTPISFGQT------------------NTVEKIPVN---PGE 2351
            :::.|         .|:|..|.:   :..|:|                  .||..:...   .||
Mouse  1686 KNLKMWFLEESNESEKVVPTNEV---MPGGETLNLRIDSIFIVLEAGIGHRTVPMLLAKACFSGE 1747

  Fly  2352 -------VQLY-HFRSCSHVQELTFFITNP--KTLLVDSSD-----SVHIALK-------FEDEE 2394
                   :.|: |.....|.....|.:..|  :.|.:|.:|     ::.|.:|       .|.:.
Mouse  1748 SKNWLSLINLHCHLELEVHYYNEMFGVWEPLLEPLEIDQTDDFRPWNLGIKMKKKAKEAIVESDS 1812

  Fly  2395 KIHNLRVGEY----------CITLKLAKLSTTQIYILVKGQIE---------LVSMVPFNLVTEF 2440
            :..|.:|.||          .:.:.|:|.....:..||:...|         |..:.||.:....
Mouse  1813 EAENYKVPEYKTAISFYSRDQLNITLSKCGLVMLNNLVEAFTEAATGSSSVFLRDLAPFMIFNSL 1877

  Fly  2441 --------------------REEEINYDESTPPEHLLLSKERSSYYQNVKRNADINMRLKLTAGL 2485
                                :..|:..|||       ||.:    |...|.|...|....|::.|
Mouse  1878 GLTVSVSPSDSFSVLNVPLAKSYELKNDES-------LSMD----YVRTKDNDHFNAMTSLSSKL 1931

  Fly  2486 GRGRTGDIPLKTNNNLPWLVKVP-TQSAQQFISIWVRILREDIKMDKPAEDFQPQKILICIWPIF 2549
                  ...|.|..|.....|:| |:..::..::..|....:..:....:..:..|.:....|:
Mouse  1932 ------FFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVERSIICQIDTVEGSKKVTIRSPV- 1989

  Fly  2550 EICNMLSCAVKATESTTGESSTIEAMGGRWALNTATTHATEHNIGF-TFSGILRGSSKDEYSLML 2613
            :|.|..|..:...|..|             .|..|:.. .|.||.. ::...|....:|:...:.
Mouse  1990 QIKNHFSIPISVFEGDT-------------LLGIASPE-NEFNIPLASYRSSLSLVPEDQDYQLC 2040

  Fly  2614 RTMDWHKFFYYDPTVWTIENALHKLGKS---SKRKWPLN-DPEELRVSRVLDF-ENAFDVKYQTK 2673
            ..:|:.:...||..:      |.|..:|   ||:.:.:| .||:..::.:..: |:.:|:.|.
Mouse  2041 EGIDFEEIIKYDGQL------LKKKCRSTNPSKKSFVINIVPEKDNLASLSVYSEDGWDLPYV-- 2097

  Fly  2674 ATREFSCCQGLDVTAW-------------GMFING---------TGLYVAIFMIQ-EQARLDLKA 2715
                        :..|             ..:|.|         .|....|:.:: :||:|.||
Mouse  2098 ------------LHLWPPILIRNLLPYKVAYYIEGIENTVVTLSEGHSSQIYNVEMDQAKLHLK- 2149

  Fly  2716 NSLQMMPKL----KSAFTI-----DVRFDNGWKSSTPICLEDFTQKSSSNAGRSLYLRYNSFVDI 2771
                ::..|    ||.|.|     |:.|.|.      .||   |:...|:...::::.||:...:
Mouse  2150 ----LLDYLNHDWKSEFYIRSSQQDINFINF------TCL---TEMEKSDLDIAIHMTYNTGQTV 2201

  Fly  2772 V-------IVERDEVLRLILEYRQEDDGRR---------LFKLRSKFVFTNFTDVVLNALTLAMD 2820
            |       :|.:   ...:|:|:.:...|:         ||..:....|.|      |.:.|.:.
Mouse  2202 VAFHSPYWMVNK---TNRMLQYKADGIHRKHPPNYTKPVLFSFQPNHFFNN------NKVQLMVT 2257

  Fly  2821 HKENSTREEVEAYSICKKARSLVSSESTKNCSGNAMDVFYDLNAHKAKHNCDTAFVYFVCFSV-- 2883
            ..|.|.:..::.          |.|.....|.|..|:....:..:.:..|. |..|.|:.|.:
Mouse  2258 DSELSDQFSIDT----------VGSHGAIRCKGLKMEYQVGVTINLSSFNI-TRIVTFIPFYMIK 2311

  Fly  2884 ------------GGSREISIPIPLAVPFTRRCFSLQAGPESIPLMITLIEKDNVHYLNVFRDTAP 2936
                        |..:.:|:.:..::||         .||:         ..|:..:.|.|...|
Mouse  2312 NKSKYHISVAEEGSDKWLSLDLEQSIPF---------WPEN---------ASNILLIQVERSEDP 2358

  Fly  2937 -----------AIVISNNTNVKFIVAQTSASENSNVSCTNSEFVGRNFEWNQLVLPHSNCYYTPP 2990
                       .|::..|..:..|:|:.:.:|:|.| .|.|::  .:.....|::.|:.   :.|
Mouse  2359 PKRIYFNKQDNCILLRLNNELGGIIAEVNLAEHSTV-ITFSDY--HDGAATFLLINHTK---SDP 2417

  Fly  2991 QMYANFPDVEFTMCNLSLAVYKDKLCAKNKI--AWSKPIRTDK-SW---QKFLHVPHHGDVKVVV 3049
            ..|.          ..||...:|.|.....:  .|:.|:.:.| .|   |.:..|.|..|:...:
Mouse  2418 VQYN----------QSSLGEIEDSLPPGKAVYYTWADPVGSRKLKWSCGQSYGEVTHKDDMMTPI 2472

  Fly  3050 CDKHRAIRLNIYYIAQQ-----------LEFSVKDLRSRLTKPENVLMPSQEQAAPRPDESSEQE 3103
            ....:.|.|..::...|           .:.:.:..::.|.:.| |::..|:......:..::||
Mouse  2473 SVGKKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAELE-VVLALQDVGISLVNNYTKQE 2536

  Fly  3104 NDTKRVTLPNMVTCAHFNEECESKTQTRIKIFIKSFVFSLQTDNRE-------NDFVKTEVCNI- 3160
            .....:|..::|.      |.:.|.:.|.|.........|:.:.||       .|.| .|:.||
Mouse  2537 VAYIGITSSDVVW------EAKPKKKARWKPMSVKHTEKLEKEFREYTEASPLEDKV-VELDNIP 2594

  Fly  3161 -----------------------YADDSMLIYDDDDDQRELRLQLPNLQVDNQLYSSGKYDFPVL 3202
                                   |.....:.|:....|...|:|:..:|:.||::.:   .||.:
Mouse  2595 VRLTPSGNDMKILQPHVIPVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGA---IFPFV 2656

  Fly  3203 LCAEKLYRRNC--SLPQVYDLDHVYKQQAQRTPVSLFTFIFYQDEMQLQNVRCQIPPFRVYIED- 3264
            ....|..|...  |.|:.:....:..:.|..:.:|                  :|..|:|.|::
Mouse  2657 FYPIKPPRSVTMDSAPKPFTDVSIVMRSAGHSQIS------------------RIKYFKVLIQEM 2703

  Fly  3265 ------AYLNQLLEALVECEPSNCV----YSPPVEQDQILLPAGMTLLPDQVVAQSLYISEPLRL 3319
                  .::..|.:.:.:.|.:...    :...||..:          .:..|..|:..|:....
Mouse  2704 DLSLDLGFVYALADLVTKAEVTEKTEVEHFHKDVEAFE----------QEYEVVSSVDQSQVNLF 2758

  Fly  3320 NSFTVEPLNLLLSVHTSSRLYIALD----------HS--------------------PLSFSRYE 3354
            ..|.:.|:.|.|||..||....|.|          ||                    .|:|....
Mouse  2759 EYFHISPIKLHLSVSLSSGRDEAKDSEQHGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFELN 2823

  Fly  3355 RQQILTVPLRFGQSLGLHYLSGAIFGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGLFRG 3419
            .|...|..|:  ..:..||...||.....::..|::||:|.||.|.||.|:..|...|.||..:|
Mouse  2824 YQFHTTSELQ--SEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQG 2886

  Fly  3420 PWGFLVGVTQGSASLLRNVTAGTVNSVTKLAGSVARNLDRLTLDAEHIELTEARRRARPQGFADG 3484
            |..|:.|:..|..:|:.....|...:.:|:..::|:.:..:|:|.::.:........:|.|..:|
Mouse  2887 PEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREG 2951

  Fly  3485 LTQGLTGLGISLLGAVGGLAHHTL---EARSSVGVIAGLTKGIVGALTKPISGAAEMLALTGQGV 3546
            :|:|..||....:..:.|:....:   :...:.|...|:.||:|||:|:|..|..:|.:.|.||:
Mouse  2952 ITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVTRPTGGIIDMASSTFQGI 3016

  Fly  3547 LHTVGFNAMPQQVEPSFIRNVALHGSSNRIWSYLPEELSRDQML------------FFSEIMLQI 3599
            ......:.:.....|.|.....:      |..|...:.|.:|||            :|:.:|:..
Mouse  3017 KRATETSEVESLRPPRFFNEDGV------IRPYRLRDGSGNQMLQVMENGRFAKYKYFTHVMINK 3075

  Fly  3600 STQL---RPALLFLT 3611
            :...   |..:||:|
Mouse  3076 TDMFMITRRGVLFVT 3090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13B	NP_651753.2	Chorein_N	5..117	CDD:289396	37/123 (30%)
		VPS13_C	3319..3468	CDD:293514	46/178 (26%)
		ATG_C	3473..3546	CDD:286423	21/75 (28%)
Vps13a	NP_766616.2	MRS6	4..>2005	CDD:227376	474/2809 (17%)
		Chorein_N	4..113	CDD:289396	32/110 (29%)
		VPS13	142..371	CDD:293513	51/314 (16%)
		TPR 1. /evidence=ECO:0000255	212..245		6/58 (10%)
		TPR 2. /evidence=ECO:0000255	373..406		11/81 (14%)
		VPS13_mid_rpt	568..791	CDD:293515	55/346 (16%)
		FFAT. /evidence=ECO:0000250|UniProtKB:Q96RL7	838..844		3/12 (25%)
		VPS13_mid_rpt	1141..>1236	CDD:293515	22/126 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1343..1365		3/21 (14%)
		TPR 3. /evidence=ECO:0000255	1806..1840		6/33 (18%)
		TPR 4. /evidence=ECO:0000255	1999..2034		8/48 (17%)
		SHR-BD	2202..2445	CDD:284143	51/296 (17%)
		Required for mitochondrial localization. /evidence=ECO:0000250|UniProtKB:Q96RL7	2607..3166		109/523 (21%)
		VPS13_C	2758..2935	CDD:293514	46/178 (26%)
		ATG_C	2938..3017	CDD:286423	22/78 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5043
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930