Protein Alignment Vps13B and Vps13d

DIOPT Version :9

• Sequence 1: NP_651753.2
• Gene: Vps13B / 43550
• FlyBaseID: FBgn0039727
• Length: 3731
• Species: Drosophila melanogaster
• Sequence 2: NP_001263431.1
• Gene: Vps13d / 230895
• MGIID: 2448530
• Length: 4390
• Species: Mus musculus
• Alignment Length: 4738
• Identity: 859/4738 - (18%)
• Similarity: 1484/4738 - (31%)
• Gaps: 1693/4738 - (35%)

  Fly     4 LESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELS 68
            ||..:..:|.:|:.|||.|...:...|:|.:|.|..:||.|:.:.| :||.||.|:.:|.|.:::
Mouse     2 LEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDAL-KELELPFEVKAGLIGKVT 65

  Fly    69 ILVPWTKLMSEPVKIVINTIEFVA---KLPD--------SESKQRRASFQR-EQRRKSKRESVEQ 121
            :.:|:.:...:|..|.|:.:..:.   |:.|        .|.::::|..|. |:|.||:|.
Mouse    66 LQIPFYRPHVDPWVISISGLHVIGGPEKIQDFNDEKEKLLERERKKALLQALEERWKSERR---- 126

  Fly   122 PDQTKSPGPAS-SSSVVNKIINNINLQCHNIILKYVEDDI-------VVSMNVQTLNFSSAGEDW 178
             .|...|...| ::|||.:|:.||.|:..::.|:: ||.:       ...:.::.::..:|..:
Mouse   127 -QQKGEPYWYSVTASVVTRIVENIELKIQDVHLRF-EDGVTNPSRPFAFGICIKNVSMQNAANE- 188

  Fly   179 KPTMVDIHPVSVVMR-KLLQVSDLTICLDKRNT--------------AGRIE----------VCQ 218
                    ||..:|| |.|.|::.:|..|...|              |..:|          ||.
Mouse   189 --------PVQKLMRKKRLDVAEFSIYWDVNCTLLGDLPQAELQEAMARSMESRSHHYILEPVCA 245

  Fly   219 EPVLYR-CT-----------LECRVLRKYNANTVSTTSTTRIGVFTKSLDINVSSLQF----PMV 267
            ..:|.| |:           :||.:..:.....:|.....:|..|.|.|:.....|:|    |.|
Mouse   246 SALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQIMAFLKELERKERQLKFRKWKPKV 310

  Fly   268 ----------------------------------------------------------------- 267
                                                                             
Mouse   311 AVSKNCREWWYFALNANLYEIREQRKCWTWDFLLHRARDAVFYTDRYFNKLKGGVLSADDKEEMC 375

  Fly   268 ----------MRLVKMLL------------ELKPAEFEDDPQNPEDQEAVA-------------- 296
                      :::::.|:            .|:..:|:....:|.|.:...
Mouse   376 RIEEEQSFEELKILRELVHDRFYKQEELAESLREPQFDSPGTSPGDPDGSGGSGMLQYLQSWFPG 440

  Fly   297 ----EGSESQQGTESAGRSV----FWWAWSLLPS---FDTEAPSSSCDTPT--GHAFDLGVYAEE 348
                .|.:|.:|....|.:.    .|....:|.:   ||..|.:|..:|.|  .|.|      .:
Mouse   441 WGGWYGQQSPEGKVVEGLTAESHEHWTPEEILGTEEFFDPTADASCMNTYTKRDHVF------AK 499

  Fly   349 LNFQLK----------------NSEYFTDQSMGGIKRI------RYTPILRISLGGLYY-----E 386
            ||.||:                |...|.......:|.:      |.:.:|.:.||||:.     |
Mouse   500 LNVQLQRGTVTLLHKEQGTAHANESAFMQLEFSDVKLLAESLPRRNSSLLLVRLGGLFLRDLATE 564

  Fly   387 RTIL---------KECDWANVKAGLSSMCMEPLGAYRSDD--------LVDRN------------ 422
            .|:.         ||....:...||.:...:....|.:.|        |.:||
Mouse   565 GTMFPLLVFPNPQKEVGRVSQSFGLQTASEDRSDQYSAADPDNPVFEMLYERNPVHSHFERRLHV 629

  Fly   423 -------LVNTQEFQQERSFIDKSLFDENYMFAERSWCSYNYADYVARNTD--------EYMLFR 472
                   :.|.|..::...|..|.....: .|..:|......|:...|..|        |.....
Mouse   630 STRPLNIIYNPQAIKKVADFFYKGKVHTS-GFGYQSELELRVAEAARRQYDKLKVQTKAEIRQTL 693

  Fly   473 SPVLAFDVIEHRVPKPSSHPVAESQLRDLGVRIQYRL-LSA-GITFHFSQSFVQVKKVISDLIR- 534
            ..:|..|.||            ||:      |...|| :|| .:.|....:|.....|:.||.|
Mouse   694 DRLLVGDFIE------------ESK------RWTVRLDISAPQVIFPDDFTFKNPVLVVVDLGRM 740

  Fly   535 ----------------------PYDYPGYRSESMKDEDRGVPEPENKNSEMTIP------DLEYL 571
                                  .:....|::..........||..:.|.|.|.|      ..|.|
Mouse   741 LLTNTQEDSRRKSGDGSASEENQFSDDEYKTPLATPPSTPPPETSSSNGEKTPPFSGVEFSEEQL 805

  Fly   572 MG-LVPTCNY-KIELRNIVVQLYPRQQQDESSAINQHQL-TTTVRQSLLPYLQLKISLV---EGT 630
            .. |:.|..| :..|..:.:|:...:.:|....:....: .|.|.:....:|||:..|:   :..
Mouse   806 QAHLMSTQMYERYSLTFMDLQVMVGRVRDNWKRVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPK 870

  Fly   631 MCGPVNPVRLVQLITHLEEKPRDVVNACYNCFHFNVKNLALMIMNTTPDNG------RAKLLNIP 689
            ..|.|....|..|..|:.|   |.::|..|||       ||:   |||:..      |.|:.
Mouse   871 YPGAVLSGNLPDLKIHINE---DKISALKNCF-------ALL---TTPETKPSDTQIREKIF--- 919

  Fly   690 RVQVNWNRLLAPHLWRQNEAP---LETS--EIKSEIITLEFSKRELIIAKRLVPLISSFSGQDLC 749
                            ..|.|   |:.|  .:...|:.||...||:::..:|:
Mouse   920 ----------------PQEGPRGSLQDSVMNLTQSIVMLEQHTREVLVESQLL------------ 956

  Fly   750 DLAHIVAN---VNVNSD---VIKLQSVGTKLNLVYHKYHTHLAAVGSLQGVH----TDAVHTKMN 804
             ||....|   :.|.|.   :..|:..||..:.|...|...::..     ||    .|.:.|...
Mouse   957 -LAEFKVNCMQLGVESSGRYISVLKVFGTNAHFVKRPYDAEVSLT-----VHGLLLVDTMQTYGA 1015

  Fly   805 IRNVVLSTSKNADNKWLEMQCQFPLEEVHSE--QEKIPGTVVCLWLEPFRITTDIYLLQFLNFSD 867
            ..::::::.||       :....|...:...  |..:.|..|.       ..||:..|     :|
Mouse  1016 DFDLLMASHKN-------LSFDIPTGSLRDSRAQSPVSGPNVA-------FQTDVTTL-----ND 1061

  Fly   868 NSGRQITKDKEVETDLESVNQSEPPITQSVSNYSTISASAIAFN---DFQPRRISRNNSRKISVP 929
            .|...::.:|.:..:.||:.:.|         |..:|:...:.|   ..|...:..||...|..|
Mouse  1062 QSATSVSLEKILTKEQESLIKLE---------YQFVSSECPSMNLDSTLQVISLQVNNLDIILNP 1117

  Fly   930 EETVHL--------SSERDERHTQAEPLTIPVANKPQPSNFDTTDFVKRLTKMVVL-------VE 979
            |..|.|        ..|:|:             ..|||.   .||..:.:.:...:       .|
Mouse  1118 ETIVELIGFLQKSFPKEKDD-------------VSPQPL---MTDLERSIVEQGTIQSTYEQNTE 1166

  Fly   980 IAQAKIDVCEVMMRKTPGHTDVEYTSIRLPHMKV--------------KSGNCEAIQ-----RGN 1025
            :| .:|....:::.:|.|..|.|....::....:              .:|:...:|     :.|
Mouse  1167 VA-VEIHRLNLLLLRTVGMADGERHGRKIATASIGGTKVNVSMGSSFDMNGSLGCLQLMDLTQEN 1230

  Fly  1026 IRG--VIPVASNTELLNWVFDLNEFNVCYRRANVTEMIIAPVRTTITLALSFKTSDKVDGSKGKE 1088
            ::.  |:.:.::....|.|.|:..|...:.|..         ...:|.||||..::     |.|:
Mouse  1231 VKSQYVVSIGNSVGYENIVSDIGYFESVFVRME---------DAALTEALSFTFAE-----KSKQ 1281

  Fly  1089 DKCANTCSINVHVDMSAINIFAQRVKLLHEHCLIISKMYGSLCPDEPASKWQTGKMKPRLEVYTG 1153
            :...|....::|.:.||        |.|.|..|.:.::     .:...|..::...|....:.|.
Mouse  1282 ECFLNLKMASLHYNHSA--------KFLKELTLSMDEL-----EENFRSMLKSAATKVTTVLATK 1333

  Fly  1154 SAQNYPVIKEFLELDPNFEAPKVKSAP-----------------------------KSSVILFCQ 1189
            :|       |:.|:...||.||....|                             :|.|:
Mouse  1334 TA-------EYSEMVSLFETPKKTREPFVLEENEIYGFGLPSPRSDTVKLILNINIESPVV---- 1387

  Fly  1190 WTIPR----------------ISFEMENSNDFKHSKIVMSLEDLLLNIDKHSDFNKITTKI---E 1235
             :|||                |...:...:|.:..::.:.::|:.|       ::...|::   :
Mouse  1388 -SIPRRPGSPELLVGHLGQIFIQNFVAGDDDSRSDRLQVEIKDIKL-------YSLNCTQLAGRD 1444

  Fly  1236 NFG---------------LNYYEEKH-EEWEKIDDLH----IKMLGDST------NLPLISVVIT 1274
            |.|               :|..||.| ...:..:.||    ..:|.::|      .:|:......
Mouse  1445 NAGPEVNRTFCPPSGLASVNSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESEL 1509

  Fly  1275 TVSLEDLYAKIGARNPHNKQHTISEVLIE---VQPIEMVLN---LDQITEFMVPICEVLEIIGNS 1333
            |.||..           ::..|.|.:.||   |.|:::||.   .:|:.:.|..:....::...:
Mouse  1510 TFSLSP-----------DELGTSSIMKIEGKFVNPVQVVLAKHVYEQVLQTMDNLVYSEDLNKFA 1563

  Fly  1334 ASAQSANKPSAPVPSKITTVQDLPMVHLNSKGIYVYLPL-STGKKSCSV---------------- 1381
            |||.::..|::|:|...:..:  |.|.....|::.:... ||.:||.||
Mouse  1564 ASAPTSPCPNSPLPQLSSCGE--PCVEKKENGLFSHSSFSSTSQKSLSVKEAKAFTQIQANFCIS 1626

  Fly  1382 -----------------LLLRIESIQLTPSLENP-------LVRQLVRPDIYQKAAELNMLS--- 1419
                             :.|:.:..::..|.::|       .:|.|:..|:.:|..:....|
Mouse  1627 ELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKSLMV 1691

  Fly  1420 -----TPGALVEDRQ------------------------------YELSVRRVSLSTGNWKQTQE 1449
                 .|.:|.:...                              ::|..|.:|......|:.|:
Mouse  1692 SRGAPKPSSLAQKEYLSQSCPSVSSVEYPDMPRSLPSHMEEAPNVFQLYQRPISTCRKKPKEAQD 1756

  Fly  1450 YRIEKT--LASKHDNPAFEWNNQSQSTELDHMEIF----KDFDFIMIYAPAISYDRFLVCGQS-- 1506
            ....:|  .:...|.|............|.|:.||    |..:|      :.||.|.   .:|
Mouse  1757 KSYPQTPPPSPSVDEPNMLVGKSKFDDSLVHINIFLVDKKHPEF------SSSYGRI---NRSID 1812

  Fly  1507 VEYNCATDFVASLNTHQISLISCIIVRAQRLGCIIDQVCVK---NAELPKARSHKTLGNISKYNS 1568
            |::|| .|.:.:|.|.      .:|:....:|...|...:|   ...|...::..:....|::..
Mouse  1813 VDFNC-LDVLITLQTW------VVILDFFGIGSTADNHAMKVPPEGLLQNVKAESSASMESEHQE 1870

  Fly  1569 VDNSIYFPADPKVFKKDTWIPKSSKKLVSERLSYTNA----------------STSFTDAKGSSD 1617
            ..||   ..|.||......:.|::.:|....:|...|                |.|.:|.....|
Mouse  1871 PVNS---KLDLKVHSLSLVLSKATSELAKANVSKLMAHMEMIEGDLALQGSIGSLSLSDLTPHGD 1932

  Fly  1618 YF------------------YGS----CQSDSGIHLGTRMKG----YSRSLAAEEI--------- 1647
            ::                  ||.    .|.:..|.:..:|..    :::...||.:
Mouse  1933 FYRERFTTSGEEALIFQTFKYGQPDPLLQREHDIRVSLQMASVQYVHTQRFQAEVVAFIQHFTQL 1997

  Fly  1648 -NRSGRQ---------------------------PFVLSYPSSVS---FVAGIFVLKIYD----- 1676
             :..|||                           |.:|...||.|   .||.:..||:.:
Mouse  1998 QDILGRQRAAIEGQTVRDQAQRCSRILLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFA 2062

  Fly  1677 -----------------------------VLELEELERPVMKPLFLMTVS-----------QPSF 1701
                                         :...|:.:.|.::.||:|..:           .||.
Mouse  2063 GFPGTFSLQDKESVPSASPAGTPKHSMRKMTTTEDPKGPQVQGLFMMPPAGVGLGSLKSDFVPSA 2127

  Fly  1702 MSTQNFKAAVTQASIFNVN----------ISVAKADVD-----------GKVDSERFNESVFAT- 1744
            ...|..:.||...|..:.:          |.|...|:|           .|.......:.:|.:
Mouse  2128 SIKQRGQQAVPPVSQSSSSPEDHVCLLDCIVVDLQDMDIFAAERHPREGSKASEHSSGDLIFPSY 2192

  Fly  1745 LPGQLGSSGIPPPLLTIKTQYDRLHQKEV------------------DVELRKPILLR-ICENTI 1790
            ...|.|.|.:..| ..:|.|.:|...||:                  .::|.|..|:| :.||.:
Mouse  2193 FVRQTGGSLLTEP-CRLKLQVERNLDKEISHTVADISVHGSLSSVHCSLDLCKYKLIRGLLENNL 2256

  Fly  1791 KQLASDVF--------RIYTVL----HETPCF-----NVRSPRPVPEGSQLRQLKMNCYNADRFH 1838
            .:...|..        ||:|||    :...||     ||......|:|      |....:..||.
Mouse  2257 GEPIEDFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKG------KEGTGSLARFD 2315

  Fly  1839 L-SCDRITAKFYDEERSYKCSFVWLDVSTRIKFSSRPQKAVIRSNIGSFYVQSGEKMLLHPLLMR 1902
            . .|..:...|.::.:|     :.|...:.:.|.:|               .||:|    |....
Mouse  2316 FKKCKLLYESFSNQTKS-----INLVSHSMMAFDTR---------------YSGQK----PSHGM 2356

  Fly  1903 LSV-DLVSEPWSEELLVNATLKLNYLHI----DAGVFSILQLQKAQQGVNRIREYADREWQQFLR 1962
            .:| :.:.:|.........::::. ||.    |:..|:::        :|.:|.:...:|  .|.
Mouse  2357 TNVFNCIFQPSKSSSATQGSIQIE-LHFRSTKDSSCFTVV--------LNNLRVFLIFDW--LLL 2410

  Fly  1963 SRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRAGAFQFVYLNSES-VLPMPY 2026
            ....|.||.|:...|:   ||:..          .||                 :||| |:|...
Mouse  2411 VHDFLHTPSDIKKQNV---TPARH----------RNA-----------------SSESAVVPKTV 2445

  Fly  2027 QVQIIKKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRMEYFSETHETFLHYCDFMLSET 2091
            :..::.|...                     :|||...|:..::   :.|...|:...|....:|
Mouse  2446 KSGVVTKRSS---------------------LPVSNERHLEVKV---NVTGTEFVVVEDVSCFDT 2486

  Fly  2092 S------TKQLT-PP---DRPICATIWRVVILQSLISVDGTCFEGSE-DEDLSI-EYLQSDFKVD 2144
            :      |..|| .|   |||...:::.:.:.        :|..|:| |..||| :.:|...::.
Mouse  2487 NAIILKGTTVLTYKPRFVDRPFSGSLFGIEVF--------SCRLGNEQDTALSIVDPVQIQVELV 2543

  Fly  2145 ENNDFILHPKVLVGCMRIDTVFRAEKVPK-LQLLLCCQDIELNFVNQTDNTGELPKQLNKYRLRQ 2208
            .|:.:    :...|.|   ..|.:|..|. |::.|...||.|:: |.......:.|.:.:.....
Mouse  2544 GNSSY----QNSSGLM---DAFNSEDFPPILEIQLQALDIRLSY-NDVQLFLAIAKSIPEQASAA 2600

  Fly  2209 TPNITQTFLTVHVEDLQMH----SRI------YSRNDFSLQTEMR-ARVKCLDYGFLNMLDVL-- 2260
            .|:.:    .:.|:.:...    |||      .||:......|:: ||::.|.:...:....|
Mouse  2601 APDSS----ALEVDSISCSLPGASRIGEDVREGSRHTLDPVLELQLARLQELGFSMDDCRKALLV 2661

  Fly  2261 ----------------EPMKFSSYVRLT--DYPRSL---------VQAN-----FLVDKL----- 2288
                            ||:|..|.|..:  |.|.::         |:|.     |:.|.:
Mouse  2662 CQGQLKKAASWLFKNAEPLKSLSLVSSSSRDNPGTMPAPRISGVEVKAESVCICFIDDCMDCDVP 2726

  Fly  2289 -------RLNCGPHV-------IHTLLSSKYH------WQEVL---------QQKDVRHVLMPKL 2324
                   |||...|:       .|..||..|:      |:..:         ||:....:..|:|
Mouse  2727 LAELTFSRLNFLQHIRTNPEGFAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQASSRLHPPRL 2791

  Fly  2325 VIVNRIQTPISFGQTNTVEKIPVNPGEVQLYHFRSCSHVQELTFFITNPKTLLVD--SSDSVHIA 2387
            .:..:.:..:....|:.:                       :..:|:..::.|.|  ..|....:
Mouse  2792 KLEAKAKRRLDINITSVL-----------------------IDQYISTKESWLADYCKEDKETES 2833

  Fly  2388 LKFED--EEKIHNLRVGE-----YCITLKLAKLSTTQIYILVKGQIELVS----MVPFNLVTEFR 2441
            .|.||  ...:.....|:     |..|...|.|:..:..|..:.:::...    .|||.|
Mouse  2834 AKTEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEVKTPKRRQPFVPFAL----- 2893

  Fly  2442 EEEINYDE--------STPPEHLLLSKERS------------------SYYQNVKRNADINMRLK 2480
               .|:..        :|.|....||...|                  |.::.|....:|....:
Mouse  2894 ---RNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGAFLDDAHNVSEWREVLTGEEIPFEFE 2955

  Fly  2481 LTAGLGRGRTGDIPLKTNNNLPWLVKVPTQSAQQFISIWVRILREDIKMDKPAEDFQ-------- 2537
            ....|....|.|:.:              ...|..::.|.::  ..:.:||....|:
Mouse  2956 ARGKLRHRHTHDLRI--------------HQLQVRVNGWEQV--SPVSVDKVGTFFRYAAPDKNS 3004

  Fly  2538 ----------------PQKILICIWPIFEICNMLSCAVKATESTTGESSTIEAMGGRWALNTATT 2586
                            ||.....:.|           |:...:.|.|.|..:.:..|.||.....
Mouse  3005 SSSTIGSPSSRTNIIHPQVYFSSLPP-----------VRVVFAVTMEGSARKVITVRSALIVKNR 3058

  Fly  2587 HATEHNIGF----------TFSGILRGSSKDEYSLMLRTMDWH---------KFFYYDPTVWTIE 2632
            ..|...:..          ....|:.|   |.:::.|....|.         .||...|..||
Mouse  3059 LETPMELRLDSPSAPDKPVVLPAIMPG---DSFAVPLHLTSWRLQARPKGMGVFFCKVPIHWT-- 3118

  Fly  2633 NALHKLG-KSSKRKWPLNDPEELRVSR---VLDFENAFDVK----YQTKATREFS---------- 2679
            |.:.... .||||:....|.|:.|..|   .:..||..|..    :...|.:.|.
Mouse  3119 NVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLP 3183

  Fly  2680 ----C----CQGLDVTAWGMFINGTGLYVAIFMIQEQARLDLKANSLQMMPKLKSAFTID--VRF 2734
                |    |: ||....||.||||                ||......:|...::..|:  |..
Mouse  3184 TVVICNLLPCE-LDFYVKGMPINGT----------------LKPGKEAALPTADTSQNIELGVSL 3231

  Fly  2735 DNGWKSSTPICLEDFTQKSSSNAGRSLYLRYNSFVDIVIVERDEVLRLILEYRQEDDGRRLFKLR 2799
            :|     .|:|.|......:.|        |...:.:..|.|.: |.|.:......:|.....:.
Mouse  3232 EN-----FPLCKELLIPPGTQN--------YMVRMRLYDVNRRQ-LNLTIRIACRAEGSLKIFIS 3282

  Fly  2800 SKFVFTNFTDVVLNALTLAMDHKENSTREEVEAYSICKKARSLVSSESTKN-------------- 2850
            :.:...|.|.:   .|....|:.:.....:.|.:.:.:....|:...:.|.
Mouse  3283 APYWLINKTGL---PLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIH 3344

  Fly  2851 -------CSGNAMDVFYDLNAHKA-KHNCDTAFVYFVCFSV--GGSREISIPIPLAVP------- 2898
                   |.|.::|....:.|.|. :.......:|.:...|  |..|.|...:.:..|
Mouse  3345 PEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNK 3409

  Fly  2899 ------FTRRCFSLQAGP-------ESIP----------------LMITL-------------IE 2921
                  |.:|.|:...|.       .::|                |.:.|             :.
Mouse  3410 SSHKLAFAQREFARGQGTANPNGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVN 3474

  Fly  2922 KDNVHYLNV------------------------FRDT---APAIVISNNTNVKFIVAQTSASENS 2959
            |:|..::|:                        |.||   .|...|.|.:.|..:..|...:| .
Mouse  3475 KNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRIDNFSKVPVVFTQHGVAE-P 3538

  Fly  2960 NVSCTNSEFVGRNFEWNQLVLP-------------HSNCYYTPPQ-----MYANFPDV--EFTMC 3004
            .:.......:..::.|::..||             ..||.....|     .|.||..:  .:|..
Mouse  3539 RLRTEVKPMMSLDYAWDEPTLPPFITLTVKGAGSSEINCNMNDFQNNRQLYYENFIYIAATYTFS 3603

  Fly  3005 NLS------LAVYKDKLCAK---------NKIAWSK--PIRTDKSWQ-----KFLH----VPHHG 3043
            .|.      :|.:|...||:         .::...|  |.:..:.|:     ...|    |||:.
Mouse  3604 GLQEGKGRPVASHKAITCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSAVPHNP 3668

  Fly  3044 DVKVVVCDKHRAIRLNIYYIAQQLEFSVKDLRSR---LTKP------------------------ 3081
            :..........:..|:|..:|     :|.|.|..   |.||
Mouse  3669 NKPSATRSIEGSAILDIAGLA-----AVTDNRYEPLMLRKPDRRRSTTQTWSFHEGKLTCGLHGL 3728

  Fly  3082 ---------------ENVLMP--SQEQAAPRPDESSEQENDTK--------RVTLPNMVTCAHFN 3121
                           |.||.|  |.|...|.|.|........:        ||............
Mouse  3729 VVQAKGGLSGLFDGAEVVLGPDSSMELLGPVPPEQQFANQKMRPGSGMLSIRVIPDGPTRALQIT 3793

  Fly  3122 EECESK-------------------------TQTRIKIFIK-------SFVFSLQTDNRENDFVK 3154
            :.|:.|                         |...:::.::       |.:..:.   .|..|..
Mouse  3794 DFCQRKSERSSYEVEELPVTEQELQKLRNPDTHQELEVLVRLEGGVGVSLINKVP---EELVFAS 3855

  Fly  3155 TEVCNIYADDSMLIYDDDDDQRELRLQLPNLQVDNQLYSSGKYDFPVLLCAEKLYRRN------- 3212
            ....||:       |........|.|.:.::||||||..:.:   |.:|....|...|
Mouse  3856 LTGINIH-------YTQLAASHMLELSIQDVQVDNQLIGTTQ---PFMLYVTPLSNENEVIETGP 3910

  Fly  3213 ------CSLPQVYDLDHVYKQ---QAQRTPVSLFTFIFYQDEMQLQNVRCQIPPFRVYIEDAYLN 3268
                  ...|....|.::||.   .|||                          |.|.||:..|.
Mouse  3911 AVQVNAVKFPSKSALTNIYKHLMVTAQR--------------------------FTVQIEEKLLL 3949

  Fly  3269 QLL--------EALVECEPSNCVYSPPVEQDQILLPAGMTLLPDQVVAQSLYISEP-LRLNSFTV 3324
            :||        |:.||....| ::....||       |.|  |.:...::|.||.| ::|:.||.
Mouse  3950 KLLSFFGYDQAESEVEKYDEN-IHEKTAEQ-------GGT--PTRYYFENLKISIPQIKLSVFTS 4004

  Fly  3325 EPLNLLLSVHTSSRLY---------IALDHSPLSFSR---YERQQILTVPLRFGQSLGLHYLSGA 3377
            ..|.|.|....|:..:         |.||    .|:|   ||.::.:.      ..:..|:....
Mouse  4005 NKLPLDLKALKSTLGFPLIRFEDAVINLD----PFTRVHPYETKEFII------NDILKHFQEEL 4059

  Fly  3378 IFGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGLFRGPWGFLVGVTQGSASLLRNVTAGT 3442
            :..|..::||::.||:|.||....|.|        |.||.:  :|.:.|       |:||||.|.
Mouse  4060 LSQAARILGSVDFLGNPMGLLNDVSEG--------VTGLIK--YGNVGG-------LIRNVTHGV 4107

  Fly  3443 VNSVTKLAGSVARNLDRLTLDAEH-IELTEARRRARPQGFADGLTQGLTGLGISLLGAVGGLAHH 3506
            .||..|.||:::..|.: |:|..| .|....|..|...|  :.|..|:.||...::|.:..:...
Mouse  4108 SNSAAKFAGTLSDGLGK-TMDNRHQSEREYIRYHAATSG--EHLVAGIHGLAHGIIGGLTSVITS 4169

  Fly  3507 TLEARSS----VGVIAGLTKGIVGALTKPISGAAEMLALTGQGVLHTVGFNAMPQQVE 3560
            |:|...:    .|.|:||.||:||.:|||::||.:..:.|.|.|..|...:....|.:
Mouse  4170 TVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQ 4227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13B	NP_651753.2	Chorein_N	5..117	CDD:289396	35/123 (28%)
		VPS13_C	3319..3468	CDD:293514	45/161 (28%)
		ATG_C	3473..3546	CDD:286423	25/76 (33%)
Vps13d	NP_001263431.1	MRS6	1..>1270	CDD:227376	262/1412 (19%)
		VPS13	140..357	CDD:374880	39/226 (17%)
		MRS6	<2466..>3103	CDD:227376	119/720 (17%)
		UBA_VP13D	2642..2677	CDD:270491	4/34 (12%)
		SHR-BD	3277..3560	CDD:369020	38/286 (13%)
		MRS6	<3838..4300	CDD:227376	119/469 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5043
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930