Protein Alignment Vps13B and C25H3.11

DIOPT Version :9

• Sequence 1: NP_651753.2
• Gene: Vps13B / 43550
• FlyBaseID: FBgn0039727
• Length: 3731
• Species: Drosophila melanogaster
• Sequence 2: NP_001348703.1
• Gene: C25H3.11 / 173962
• WormBaseID: WBGene00016120
• Length: 3314
• Species: Caenorhabditis elegans
• Alignment Length: 4223
• Identity: 766/4223 - (18%)
• Similarity: 1357/4223 - (32%)
• Gaps: 1548/4223 - (36%)

  Fly     4 LESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELS 68
            ||:.:..:|.:|:.:|:::...:...|:|..|:|..:|:.|:...| .:|:||||:.||.:.:|:
 Worm     2 LENVVAWVLNNYIGEYLEDLNTDQLSVALLSGQVELENVPLKKTAL-RKLDLPVEVKSGLLGKLT 65

  Fly    69 ILVPWTKLMSEPVKIVINTIEFVAKLPDSESK-QRRASFQREQRRKSKR-ESVEQPDQTK----- 126
            :.||.|.:.|||..:.::.:..:.....||.: ...|..|.||:||.:. |.:|...:|.
 Worm    66 LSVPITHIRSEPWTLKLSDVLIIVGPLSSEKRYDVEAVEQVEQQRKEQMLEELELRHKTALFDLC 130

  Fly   127 -SPGPAS-----SSSVVNKIINNINLQCHNIILKYVEDDIVV-------SMNVQTLNFSSAGEDW 178
             .|.|.|     .:|:::.::|||.|..:|:.::| |||..:       .:.:|.:...:....|
 Worm   131 GIPIPESQDSWWGASLISTVLNNIQLILNNVHIRY-EDDTTIPGQTFNCGIRIQKMTMQTTNHHW 194

  Fly   179 KPTMVDIHPVSVVMRKLLQVSDLTICLDKRNT-------AGRIEVCQEP-------VLYRCTLEC 229
            ||...:....:...:| |::...:|..:.:.|       :.::::...|       ::..|:.|.
 Worm   195 KPGFAEPQKGTNTFKK-LELGGFSIYWNSKTTMTENIEDSKQLKLILAPETSSNAYIIQPCSAEL 258

  Fly   230 RVLRKYNANTVSTTSTTRIGVFTKSLDINVSSLQFPMVMRLVKMLLELKP--------------- 279
            |:.:                          :|.:||:..::.:....::|
 Worm   259 RMEK--------------------------NSSKFPLKSKVPRFKFFMRPDILGLELTRHQMTQL 297

  Fly   280 -------AEFEDDPQNPEDQEAVAEGSESQQGTESAGRSVFWW------------------AWSL 319
                   |.||...|:.:.:.....|..:::          ||                  .|
 Worm   298 RAVNREWARFERARQHRKWRPLCTIGENAKE----------WWKFAYNRVLEESRRANANRTW-- 350

  Fly   320 LPSFDTEAPS---------------------------SSCDTPTGHAFDLGVYAEELNFQLKNSE 357
              .|..|..|                           |:.|:.|..:..|.|.....:....::.
 Worm   351 --DFAHERASRFNAYCRAYRKRLIGLIANPNAIQSTVSTDDSNTNPSNALAVVPVTTSNGASSNH 413

  Fly   358 YFTDQSMGGIKRI----RYTPILRISLGGLYYERTILKECDWANV------KAGLSSMCMEPLGA 412
            ..:.:|...:|:|    :||          |:|..:.:|..:..:      :.|:::..::...|
 Worm   414 NQSLESTAIMKQIERDAQYT----------YHELHLFRETVFRKLIREKEKELGITAAPIDTEDA 468

  Fly   413 YRS------DDLVDRNLVNTQ--------------------EFQQERSF----ID---------K 438
            :.:      :.:||.....|:                    |.|::..|    :|         |
 Worm   469 FETLEPPPDEIIVDEPTAPTEPTNGGLYGWITGFFGQAQQDEKQEDNKFDFGNVDVGELKDINVK 533

  Fly   439 SLFDENYMFAERSWCSYNYADYVARNTDEYMLFRSPVLAFDV---IEHRVPKPSSHPVAESQLRD 500
            .:.:|.......||             |:..|.|...|...:   :||...:     ..:|.:.|
 Worm   534 EMEEEILDVLHESW-------------DDSTLLRRDALLAQISLRLEHLTLR-----FVDSDVHD 580

  Fly   501 LGVRIQYRLLS---AGITFHF----SQSFVQVKKVISDLIRPYDYPGYRSESMKDEDRGVPEPEN 558
             |:. |.|:|:   :|::..:    .|.::.|...::|:            |::....|.|.|::
 Worm   581 -GIE-QQRVLALELSGVSSRWELSPKQHYLSVDVTVNDM------------SVQRLRSGHPRPKS 631

  Fly   559 KNSEMTIPDLEYLMGLVPTCNYKIELRNIVVQLYPRQQQDESSAINQHQLTTTVRQSLLPYLQLK 623
            |.:|::    |.|                   ||        |.....::..||.:.....:..|
 Worm   632 KFAELS----ESL-------------------LY--------STAESTKMLLTVGRDGTDVISSK 665

  Fly   624 ISLVEGTMCGPVNPVRLVQLITHLEEKPRDVVNACYNC--------------------------- 661
            :.:..               :.::.:.||.:|....||
 Worm   666 VPMFS---------------MHYIRKSPRLIVKHMVNCRLRPVSIVYEEGALEGLSTLFSDDPTV 715

  Fly   662 FHFNVKNLALMIMNTTPDNGRAKLLNIPRVQVNWNRLLAPHLWRQNEAPLETSEIKSEIITLEFS 726
            |...:|..|....::..|..   |::| :|......::..|::...|.|....|::..    .::
 Worm   716 FDEFMKKAAQASGSSESDEA---LVDI-KVDAQNVSIIESHVFVNLELPAVRMEVRGR----GWT 772

  Fly   727 KRELIIAKRLVPLISSFSGQDLCDLAHIVANVNVNSDVIKLQSVGTKLNLVYHKYH-THL-AAVG 789
            :|||             ....:.:....:|.:||:         |...|:|..:.| |:| .|:|
 Worm   773 RREL-------------RPTTIWEPGEPIACLNVD---------GLNFNVVSKEQHLTNLKLAIG 815

  Fly   790 SLQGVHTDAVHTKMN--IRNV---VLSTSKNADN-KWLEMQC--------QFPLEEVHSEQ---- 836
                      |.:|.  |.|.   :.:||..|.. |.:...|        ..|..:..|.|
 Worm   816 ----------HMEMRDMIENTSYPLFTTSSQASQMKSISNSCPDLHKTEKSVPARQSKSHQNHHI 870

  Fly   837 ----EKIPGTVVCLWLEPFRITTDIYLLQFLNFSDNSGRQITKDKEVETDLESVNQS-EPPITQS 896
                ..:|......:::|..:||                 :|.......|..::..: .|||...
 Worm   871 PIISSSVPDESYADYIKPLNLTT-----------------MTITSATSIDNHALTSAPAPPIPSR 918

  Fly   897 VSNYS-TISASAI--AFNDFQPRRISRNNSRKISVPEETVHLSSER-------------DERHTQ 945
            |.... ||..:.:  ..:.|:.:...||.|.:|.:.|..:.::...             ||....
 Worm   919 VMKPEVTIKMTYVDKLHSQFERKYKKRNCSIEIEMDEMEMQMNRRTWTALLEMSGILGVDEHEKS 983

  Fly   946 AEPLTIPVANKPQPSNFDTTDFVKRLTKMVVLVEIA-------------QAKIDVCEVMMRKTPG 997
            .|.:|  |.||...|        |.:...:|...:.             ..::.|..:|
 Worm   984 EENVT--VTNKTTSS--------KAVASFLVGCTLRARNWRVGMPFPKNNTRLGVISLM------ 1032

  Fly   998 HTDVEYTSIRLPHMKVKSGNCEAIQRGNIRGVIPVASNTELLNWVFD---LNEFNVCYRRANVTE 1059
            :|::|.|      |::...|                |||..:..:.|   :::....|... .||
 Worm  1033 NTELEST------MELSESN----------------SNTLAMKLMVDGMRIDDSTPFYSEM-YTE 1074

  Fly  1060 MIIAPVRTTITLALSF----KTSDKVDGSK----------GKEDKCANTCSINVHVDMSAINIFA 1110
            .:|.........:..|    :|..::|.||          |::.......||..||..:
 Worm  1075 RLIMLDEQFENASSGFGGPTQTKRRLDDSKRIVIDVVKYLGEDPSRECDVSIGFHVPSN------ 1133

  Fly  1111 QRVKLLHEH---CLIIS--KMYGSLCPDEPASKWQTGKMKPRLEVYTGSAQNYPVIKEFLELD-- 1168
            |:...:|.|   |.::.  ..:..|......||        :|:|..|:.     .|..|::|
 Worm  1134 QKFYYVHTHRFFCALMEFWMQFNELMNIVTKSK--------KLKVEEGAR-----AKCSLDVDIQ 1185

  Fly  1169 --PNFEAPKVKSAPKSSVILFCQWTIPRISFEMENSNDFKHSKIVMSLEDLLLNI-DKH---SDF 1227
              .:|..|...::|:   ||..|      :..|:..|.||      :|..|...| ||:   ||:
 Worm  1186 CAVSFLMPLNSTSPE---ILLWQ------ADSMKLKNTFK------TLSSLKTEIFDKYSIESDY 1235

  Fly  1228 ---NKITTKIENFGLNYYEEKHEEWEKIDDLHIKMLGDSTNLPLI--------SVVITTVSLEDL 1281
               :.|...::...:.....:..|..:||.|.     :..||.|:        :.|:|:.::...
 Worm  1236 GYDSNIDCLLDYGDMILSNVRAHEARQIDRLQ-----NMKNLDLVGEKAFQQAAFVLTSPNVFSR 1295

  Fly  1282 YAKIGARNPHNKQHTISEVLIEVQPIEMVLNLD--QITEFMVPICEVLEIIGNSASAQSANKPSA 1344
            ...:..:...|.....|:...::..|..:..|.  ..|:|.|.:..|:|        ::..:|..
 Worm  1296 RFDLNNKFLRNLDSVFSKNAPDLTIITRISGLKWRMTTQFYVLMRAVIE--------KNFGEPMI 1352

  Fly  1345 PVPSKI-TTVQDLPMVHLNSKGIYVYLPLSTGKKSCSVLLLRIESIQLTPSLENPLVRQLVRPDI 1408
            ||...| |.:..||...:..:.|..|..||.                           ::|..|:
 Worm  1353 PVAETIPTEILQLPTDVMEVECIQKYATLSF---------------------------RMVFEDV 1390

  Fly  1409 YQKAAELNMLSTPGALVEDRQYELSVRRVSLSTGNWKQTQEYRIEKTLASKHDNPAFEWNNQSQS 1473
                 :|| |..|..|.|.::..|.        |.|:.....::|:...|   ..||| :|||
 Worm  1391 -----DLN-LEVPRKLGEQQKAVLD--------GKWQPFANVKLERARIS---FDAFE-DNQS-- 1435

  Fly  1474 TELDHMEIFKDFDFIMIYAPAISYDRFLVCGQSVEY---------NC----------------AT 1513
             |||                       |:| :.||.         ||                ||
 Worm  1436 -ELD-----------------------LIC-ERVELVDTTSNGPKNCFPVILQHTDSGKHSRPAT 1475

  Fly  1514 DFVASLNTHQISLISCIIVRAQRLGCIIDQVCVKNAELPKARSHKTLGNISKYNSVDNSIYFPAD 1578
            ...:|:|: .:.|.:.|:::...  |.:..:.:.||.:           |..|:.:|:...|
 Worm  1476 PVTSSINS-SLMLEAHIMMKKDE--CPVLTLVLCNARV-----------ILAYDWLDDLKQF--- 1523

  Fly  1579 PKVFKKDTWIPKSSKKLVSERLSYTNASTSFTDAKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLA 1643
              :.....:|||     .|:.:.|     ..|::        |..|:.|..|.|..::   |:..
 Worm  1524 --IMLYTDFIPK-----YSDEIPY-----HLTES--------GRRQTFSKTHDGAIIE---RNAH 1565

  Fly  1644 AEEINRSGRQPFVLSYPSSVSFVAGIFVLKIYDVL---ELEELERPVMKPLFLMTVSQPSFMSTQ 1705
            |.:...|       .:|:        |.:||  .|   :|..||.|.:|..|.|..|
 Worm  1566 ATDSTSS-------QFPT--------FSVKI--TLRDSDLYILENPFVKNSFAMIAS-------- 1605

  Fly  1706 NFKAAVTQASIFNVNISVAKADVDGKVDSERFNESVFATLPGQLGSSGIPPPLLTIKTQYDRLHQ 1770
                   ..::.|:|      |..|.:.:....:|:      :||...:.             |:
 Worm  1606 -------TTAVLNMN------DNGGYISANLEIQSM------KLGWCSMQ-------------HE 1638

  Fly  1771 KEVDVELRKPILLRICENTIKQLASDVFRIYTVLH-ETPCFNVRSPRPVPEGSQLRQLKMNCYNA 1834
            |:.                 :.|.|:.|.|...|| :|..|          .:|.:|.|......
 Worm  1639 KQT-----------------RNLCSNDFSITIALHIDTSLF----------VNQSKQNKGMVVTP 1676

  Fly  1835 DRFHLSCDRITAKFYDEERSYK--CSFVWLDVSTRIKFSSRPQKAVIRSNIGSFYVQSGEKMLLH 1897
            ...|...::.:..|..|....|  |...:.|        :|..||||:.     |.::..::|..
 Worm  1677 PIRHALEEQNSTTFLIEIEVVKMICRLSYKD--------ARALKAVIQG-----YTKNYIEVLKK 1728

  Fly  1898 PLLMRLSVDLVSEPWSEELLVNATLKLNYLHIDAGVFSILQLQKAQQGVNRIREYADREWQQFLR 1962
            ||:..:.....|:|                 ||..::.|.            .|:.|. |
 Worm  1729 PLIPIIVPQPPSKP-----------------IDISMYMIQ------------TEHTDL-W----- 1758

  Fly  1963 SRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRAGAFQFVYLNSESVLPMPYQ 2027
               :|                                    |||::.:
 Worm  1759 ---IL------------------------------------DDLQSNS----------------- 1767

  Fly  2028 VQIIKKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRMEYFSE--------THE----TF 2080
            :.:::.:...:|.:....|.:.|.|:               .|:||::        ..|    .|
 Worm  1768 IPLLRLSVAHVCLKKTGERIIASFHV---------------SMDYFNQRIFGWEPVIEEWKILRF 1817

  Fly  2081 LHYCDFMLSETSTKQLTPPDRPICATIWRVVILQSLISVDGTCFEGSEDEDLSIEYLQSDFKVDE 2145
            ||      ::...||          ||..|...:|.::::.|       |.|..:.:|.:.|:
 Worm  1818 LH------NKKDLKQ----------TIEWVAETKSTLNINVT-------EQLIQQSIQWNTKL-- 1857

  Fly  2146 NNDFILHPKVLVGCMRIDTVFRAEKVPKLQLLLCCQDIELNFVNQ--TDNTGELPKQLNKYRLRQ 2208
                   |.:|....|.|                       |.||  ..::..||     |.::.
 Worm  1858 -------PAILASFERDD-----------------------FRNQCTRSSSDHLP-----YVMKN 1887

  Fly  2209 TPNITQTFLTVHVEDLQMHSRIYSRNDFSLQTEMRARVKCLDYGFLNML---------------- 2257
            |......|.|. |||:........::.....|..|.:.|..::....:|
 Worm  1888 TTGCEVHFTTA-VEDVLTARSEQRKSTTRWMTVGRGQEKNFEFPARLLLYSHLEREPPRQLIVRV 1951

  Fly  2258 ---DVLEPMKFSS---YVRLTDYPR-SLVQANFLVDKLRLNCGPHVIHTLLSSKYHWQEVLQQKD 2315
               |.:.|:...|   |.|:....| .|..|..|:.....|.|..|: ||.||
 Worm  1952 SGWDEISPVNVDSCGTYFRVIKALRPQLKNARLLISVTMENDGKKVV-TLKSS------------ 2003

  Fly  2316 VRHVLMPKLVIVNRIQTPISFGQTNTV----EKIPVNP-GEVQL-YHFRSCSHVQELTFFITNPK 2374
                    :.|.|.:..||:.....|:    |.:.|.| |.|.: ..|..|:    ||.:...|.
 Worm  2004 --------IDITNHLPHPIAVQTEGTISEGGEVMSVEPNGVVSVPLEFAHCT----LTAYPVGPM 2056

  Fly  2375 TLLVD---SSDSVHIA---------LKFEDEEKIHNLRVGEYCITLK--------LAKLSTTQIY 2419
            .::..   |..||.|:         ||...:..::  |....|..::        ...|....|:
 Worm  2057 PVIEHAELSWKSVRISGEVCNQTQRLKTRSDSNLN--RFYWVCTAIRREYYPEHDFESLPGHSIH 2119

  Fly  2420 ILVKGQIELVSMVPFNLVTEFREEEINYDESTPPEHLLLSKERSSYYQNVKRNADINMRLKLTAG 2484
            ::  ..:.|.:::|.::       ||...::.    ..::..:|....:|    ||...|.:|..
 Worm  2120 LV--APLSLQNLLPIDV-------EIKIQDNV----FAIAASKSMLITSV----DITKELSITVS 2167

  Fly  2485 LGRGRTGDIPLKTN----NNLPWLVKVPTQSAQQFISIWVRILREDIKMDKPAEDFQPQKILICI 2545
            ..|.:: ..||..|    .....|......|....:.::..: |..:          .|.|.:.:
 Worm  2168 TDRLQS-QAPLLINKASIGEGTLLFTKMADSKGHLLDMYCHV-RLGV----------AQAISVSL 2220

  Fly  2546 WPIFEICNMLSCAVKATESTTGESSTIEAMGGRWALNTATTHATEHNIGFTFSGILRGSSKDEYS 2610
            |..:.|.|           .:|....|:....:|   .|.....||.           .:||.:.
 Worm  2221 WVPYWIVN-----------KSGIPLIIQQEAVKW---EAAGQMEEHE-----------KAKDRHP 2260

  Fly  2611 LMLRTMDWHKFFYYDPTVWTIENALHKLGKSSKRKWPLNDPE--ELRVSRVLDFENAF------- 2666
            ||        |.:.|.                      |.|:  .:||......||.:
 Worm  2261 LM--------FSFADE----------------------NCPKACRVRVGNAYIRENGYRSILSEK 2295

  Fly  2667 ------------DVKYQTKATREFSCCQGLDVTAWGMFINGTGLY--------VAIFMIQEQARL 2711
                        .|:::||.|..::.  |::|..      |||.|        .:.|::|.|:.:
 Worm  2296 FTLTPGVQALKLRVEHKTKPTFYYNL--GVEVRP------GTGRYKDTQVVLLTSRFLLQNQSTV 2352

  Fly  2712 DLKANSLQMMPKLKSAFTIDVRFDNGWKSSTPICLEDFTQKSSSNAGRSLYL------------- 2763
            .|......::...|....:..:....|              :.:.|||.:..
 Worm  2353 ALSVCHHDLVEMEKDHVHLAAQSSTTW--------------NENYAGRRMLCVRRADVKHWSCPF 2403

  Fly  2764 ---RYNSFVDIVIVERDEVLRLILEYRQEDDGRRLFKLRSKFVF----------------TNFTD 2809
               |..|| .:.:.:.||..|.|          |:..:.:..||                .|.||
 Worm  2404 LIDRIGSF-HVTMRDADETPRFI----------RVEIILTSAVFQITFTNADLYPPPIRIENLTD 2457

  Fly  2810 VVLNALTLAMDHKENSTREEVEAYSICKKARSLVSSESTKNCSGNAMDVFYDLNAHKAKHNCDTA 2874
            |.:      :..:|:||.......:|| |:||:|.         .|.|   ||..:|       .
 Worm  2458 VPV------LYQQESSTPARPHLRTIC-KSRSVVD---------YAWD---DLYGNK-------K 2496

  Fly  2875 FVYFVCFSVGGSREISIP-------------IPLAVPFTRRCFSLQAGPESIPLMITLIEKDNVH 2926
            .|..|..:...|.|||:|             |.||..||:|     :|..|
 Worm  2497 MVLQVFENRSKSYEISLPGPAEPLVYENSSYIQLAHSFTKR-----SGKGS-------------- 2542

  Fly  2927 YLNVFRDTAPAIVISNNTNVKFIVAQTSASENSNV--SCTNS--EFVGRNFEW---NQLVLPHSN 2984
              ..|.| ...:|:......|.::.:...:|::.:  .|.:.  |.||.|...   ::|||
 Worm  2543 --GEFTD-EQELVLETMQKGKVMLNKQCRTEDNQLWKLCADGCIENVGMNHRKRSDSRLVL---- 2600

  Fly  2985 CYYTPPQMYANFPDVEFTMCNLSLAVYKDKLCAKNKIAWSKPIRTDKSWQKFLHVPHHGDVKVVV 3049
                         ||........:.:.:||  .:||            ||::..:|   |.::.:
 Worm  2601 -------------DVLEKTGGRLMMMERDK--RRNK------------WQRWTWMP---DGRLCL 2635

  Fly  3050 CDKHRAIRLNIYYIAQQLEFSVKDLRSRLTKPENVLMPSQ--EQAAPRPDES------------- 3099
            .|..     ::...::|.|..|.:......|.|:.:..:|  :....||...
 Worm  2636 IDSP-----HLMMTSKQTEAVVVEADGLAPKGEDGVAVTQIWKVQRQRPGSGTLGVEFLHSGPTV 2695

  Fly  3100 ----SEQENDTKRVTLPNMVTCAHFNEECESKTQTRIKIFIKSFVFSLQTDNRENDFVKTEVCNI 3160
                :::|..|:.|:.| |:..|:.....:.....|..:.| |.|..||.:            .|
 Worm  2696 LIRITDREFQTRAVSEP-MIQAANKLAVLDVSITMRGGLGI-SVVNGLQEE------------LI 2746

  Fly  3161 YADDSMLIYDDD--DDQRELRLQLPNLQVDNQLYSSGKYDFPVLLC------------------- 3204
            ||....::....  |...::...:..:|:||||.||.::.  ||.|
 Worm  2747 YAHFGGIVVSARRVDKTYQMTGSVDVIQIDNQLLSSDRWQ--VLYCQPDAGQNYDDQMLELPAGI 2809

  Fly  3205 ------AEKLYRRNCSLPQVYDLDHVYKQQAQRTPVSLFTFIFYQDEMQLQNVRCQIPPFRVYIE 3263
                  |.|| ..||:..:.||....::.:.....|.|       ||:
 Worm  2810 PVTGRPALKL-EMNCTSMKHYDSFDCFRLKVCDMSVQL-------DEL----------------- 2849

  Fly  3264 DAYLNQLLEALVECEPSNCVYSPPVEQDQILLPAGMTLLPDQVVAQSLYISEPLRLNSFTVEPLN 3328
                  ||..:|:...|:...| .|:|..:.||..          ..|...:|||...:....|:
 Worm  2850 ------LLWKIVQMAQSSDAAS-SVQQRALNLPPN----------TELERHDPLRTRRWYFGTLD 2897

  Fly  3329 LL-----LSVHTSSR------LYIALDHSPLSFSRYERQQILTVPLR----------FGQSLGLH 3372
            |.     |||.|.|:      |.:......:....:|...:...|.|          ..:||...
 Worm  2898 LEMGHVGLSVVTVSKSGLPRDLRLLKQQFNVKLISFENASVALPPFRQYHYFETSSFLLESLQKF 2962

  Fly  3373 YLSGAIFGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGLFRGPWGFLVGVTQGSASLLRN 3437
            ||:........::.:|:..|:|.||.    |.|:|    ..|||      |:.|..|   ..:..
 Worm  2963 YLAELQKQTLSIIVTLDAFGNPLGLV----TDLKD----SFQGL------FIEGDVQ---RFVAG 3010

  Fly  3438 VTAGTVNSVTKLAGSVARNLDRLTLDAEHIELTEARRRARPQGFAD----GLTQGLTGLGISLLG 3498
            :..|..|||:|:|.|:|..:..||.|.:| ||.......|....:.    .|..|:.|||:.:||
 Worm  3011 LGYGLSNSVSKVASSMASGVGALTFDQDH-ELKRRHNMIRSHSSSSTPLTHLYSGVKGLGVGVLG 3074

  Fly  3499 AVGGLAHHT---LEARSS---VGVIAGLTKGIVGALTKPISG----------AAEMLALTGQGVL 3547
              |..|..|   .|:|.|   .|::.|:..|:|..:|||:.|          |.:.||:...||.
 Worm  3075 --GATAMFTNVASESRKSGLVKGMVWGVATGVVDTVTKPVQGVFDFVEGTASAMKELAMPATGVR 3137

  Fly  3548 HTVGF--NAMPQ------QVEPSFIRNVALHGSSN--RIWSYLPEELSRDQMLFFSEIMLQISTQ 3602
            .....  ..:|:      .:.|::..|:| |....  ||..|    .||:|:|.....:..|...
 Worm  3138 RATALCRVRIPRLCRNLYHLLPAYNPNLA-HAQMELLRINGY----SSREQLLDVETCLEHIDAA 3197

  Fly  3603 -----LRPALLFLTSSVLAIMQSDSED------LAF-------ASP-----ISKVDVLADRED 3642
                 :|..:|..|.......|::.|.      :|:       |.|     .|.::|..|.||
 Worm  3198 NIDRIIRQYVLISTKQCYVCRQTNGESSIVIQRIAYKYLKSVVARPPLENTFSSIEVSLDMED 3260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13B	NP_651753.2	Chorein_N	5..117	CDD:289396	33/113 (29%)
		VPS13_C	3319..3468	CDD:293514	41/169 (24%)
		ATG_C	3473..3546	CDD:286423	25/92 (27%)
C25H3.11	NP_001348703.1	MRS6	1..>2091	CDD:227376	482/2763 (17%)
		VPS13	145..369	CDD:374880	37/265 (14%)
		SHR-BD	2216..2490	CDD:369020	66/380 (17%)
		RICIN	2545..2649	CDD:238092	25/143 (17%)
		MRS6	<2732..3234	CDD:227376	132/583 (23%)
		VPS13_C	2908..3038	CDD:374881	35/146 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5043
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830