Protein Alignment Vps13B and vps13b

DIOPT Version :9

• Sequence 1: NP_651753.2
• Gene: Vps13B / 43550
• FlyBaseID: FBgn0039727
• Length: 3731
• Species: Drosophila melanogaster
• Sequence 2: XP_002934455.3
• Gene: vps13b / 100490880
• XenbaseID: XB-GENE-853604
• Length: 4027
• Species: Xenopus tropicalis
• Alignment Length: 4322
• Identity: 991/4322 - (22%)
• Similarity: 1697/4322 - (39%)
• Gaps: 1057/4322 - (24%)

  Fly     4 LESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELS 68
            ||||:||||:|||.:|:||.:..|.|:|||.|:|....|:|:|:|||:||.||...:|||||||.
 Frog     2 LESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELR 66

  Fly    69 ILVPWTKLMSEPVKIVINTIEFVAKLPD----------SESKQRRASFQREQRRKSKRESVEQPD 123
            |.||||||.||.|.|.|||:|.:.||.|          |.|..|..:...:...|.::.....|.
 Frog    67 IHVPWTKLGSESVVITINTMECILKLKDGAQDDIESCGSSSTNRSTTESAKSPVKPRKVQQAAPT 131

  Fly   124 QTKSPGPASSSSVVNKIINNINLQCHNIILKYVEDDIVVSMNVQTLNFSSAGEDWKPTMVDIHPV 188
            ....| |....|::.:::||:|:..:|:||||||||||:|:|:......:..|.|....:||...
 Frog   132 DPDLP-PGYVQSLIRRVVNNVNIVVNNLILKYVEDDIVLSVNITCAECYTVDEFWDRAFMDISAT 195

  Fly   189 SVVMRKLLQVSDLTICLDKRNTAGRIEVCQEPVLYRCTLECRVLRKYNANTVSTTSTTRIGVFTK 253
            .:|:||::..||.|:||||||.:|:||..|:|:||:|:...|:...|::......|..:|.....
 Frog   196 ELVLRKVINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYDSLNSKMPSVIKIHTMVD 260

  Fly   254 SLDINVSSLQFPMVMRLVKMLLELKPAEF-------EDDPQNPEDQEAVAEGSES---------- 301
            ||.::::..|.||.:|::::.:.|...|.       .|:|.||.....|:.|.|.
 Frog   261 SLKLSLTDQQLPMFIRIMQLGIALYYGEIGNTKDGEPDNPLNPTKDTIVSGGEEELGVGIQYPSQ 325

  Fly   302 -----QQGTESAGRSVFW--WAWSLLP---SFDTE----------APSSSCDTPTGH-----AFD 341
                 |...|..|    |  ||||.:|   |:..|          ..::....|..|     ...
 Frog   326 ELYPMQDDDEQQG----WVSWAWSFVPAIVSYGNEEEGEFGNAGLEDNTMLQGPKSHLSKDPVIS 386

  Fly   342 LGVYAEELNFQLKNSEYFTDQSMGGIKRIRYTPILRISLGGLYYERTILKE----CDWANVKAGL 402
            :|.|..:....||.:|..|:.|....::::...::|....|...|..:..|    |....|  |.
 Frog   387 MGFYCTKATITLKLTEMQTESSYYSPQKVKSREVIRWEQEGTTVEVLMNGEPFFDCQVGFV--GS 449

  Fly   403 SSMCMEP-LGAYRSDDLVDR------------NLVN------TQEFQQERS----------FIDK 438
            .::|::. :|....:|:.:|            ||.|      |......||          .:|.
 Frog   450 RAVCLKGIMGIKDFEDISNRSDEEACFFTCGENLSNKGNTYLTNSLFDYRSPENNGIRAEFILDS 514

  Fly   439 SLFDENYM-FAERSWCSYNYADYVARNTDEYMLFRSPVLAFDVIEHRVPKPSSHPVAESQLRDLG 502
            :|..|.|. .|........|.||:  .|.|....:.|:...|.       .|..|..:..::::.
 Frog   515 TLHKETYTEIAGMQRFGAFYMDYL--YTMESTSGKGPLNQQDF-------TSGKPEEQGFVQEMS 570

  Fly   503 VRIQYRLLSAGITFHFSQSFV-QVKKVISDLIRPYDYPGYRS--ESMKDEDRGVPEPENKNSEMT 564
            .:   ||:...|......|.| ::.|:::..: .::|..|.|  .:..:|::.:|.||
 Frog   571 TK---RLVIGPIDLRLDSSSVHRIMKMVACSL-DHEYEAYCSPPSATVEENKSLPSPE------- 624

  Fly   565 IPDLEYLMGLVPT---------CNYKIELR--NIVVQLYP---RQQQDESSAINQHQLTTTVRQS 615
              |:..|...:||         |...|.:.  |::..|.|   .|:....:.:|      |..|.
 Frog   625 --DVASLEEYIPTRLSCVTILKCTITITMAEFNLLGHLIPVIMGQKHASPATLN------TSFQP 681

  Fly   616 L--LPYLQLKISLVEGTMCGPVNPVRLVQLITHLEEKPRDVVNACY-NCF-----------HFNV 666
            :  ||.:::....:......|:...:|||.::.|.:...::::.|| :|:           ..:.
 Frog   682 IRPLPAIKILADKINFEHSVPMYAEQLVQTVSSLSQPSDNLLHHCYAHCYLKVFGFQAGLISIDS 746

  Fly   667 KNLALMIMNTTPDNGRA---KLLNIP-----RVQV-----------------------------N 694
            |.|....:...|....|   |||.:|     |.||                             :
 Frog   747 KGLCSSHVPVIPSFSTALYGKLLRLPQYWTSRAQVPVAEYIFELPNLTILATRAQTLLLQAIYDS 811

  Fly   695 W------------NRLLA----PHLWRQNEAPLETSEIKSEIITLEFSKREL------------I 731
            |            |..|.    |....:::.||.|.|...:.|.|:|....|            |
 Frog   812 WIYSTKNSGSSVLNEALLNEIFPTAGVKSKNPLPTLEGSIQNIELKFCSTSLVKCVSGTVGSIKI 876

  Fly   732 IAK--------RLVPLI---------------------SSFSGQDLCDLAHIVANVNVNSDVIKL 767
            .||        :|:|||                     .|..|.||     |...:.|...:...
 Frog   877 CAKAPGEVGKEKLIPLIQGPSDTRDLHRSMWLRESRKPESLLGPDL-----IAFTIQVPEQMDYC 936

  Fly   768 QSVGTKLNLVYHKYHTHLAAVGSLQGVHTDAVHTKMNIRNVVLSTSKNADNKWLEMQCQFPLEEV 832
            .|.|.             |.:.|:||:       .:|:..|:.:        ||....|    :.
 Frog   937 HSSGA-------------ALLASIQGL-------AVNVDPVLYT--------WLTYHPQ----KR 969

  Fly   833 HSEQEKIPGTVVCLWLEPFRITTDIYLLQFLNFSDNSGRQITKDKEVETDLESVNQSEPPITQSV 897
            .|.|.:.|     |...|..:                  .:::.||.|..:.|...::.|..|.
 Frog   970 SSRQAQQP-----LGSAPLAV------------------PLSRKKEDEVSIGSAPLAKQPSNQP- 1010

  Fly   898 SNY--STISASAIAFNDFQPRRISRNNSRKISVPEETVHLSSERDERHTQAEPLTIPVANKPQPS 960
            |:|  |.:....:            ..||.:|||.:.  |.:.|:...:..|.:...:..
 Frog  1011 SDYASSPVKTKTV------------TESRPLSVPVKA--LLASREGSKSSEERMKEVIGT----- 1056

  Fly   961 NFDTTDFVKRLTKMVVLVEIAQAKIDVC-------------EVMMRKTPGHTDVEY--------T 1004
               ..:.|||||        .|.:|..|             .::....||.....|        |
 Frog  1057 ---VWNAVKRLT--------LQVEIQTCCVFFPSDSLPSPSTIVSSDIPGTVRSWYHGQACMPGT 1110

  Fly  1005 SIR-LPHMKVKSGN---CEAIQRGNIRGVI--PVASNTELLNWVFDLNEFNV-CYRRANVTEMII 1062
            .:. .|.:|:.|..   .|.||  .|..::  |:........|..:|:.|:| ......:...::
 Frog  1111 LVACFPQIKIMSAGHKYMEPIQ--EIPFIVPRPIVEEGVAFPWTINLHNFSVYTLLEHQLILNLV 1173

  Fly  1063 APVRTTITLALSFKTSDKVDGSKGKEDKCANTCSINVHVDMSAINIFAQ--RVKLLHEHCLIISK 1125
            .|:..|.|||:   ||..:.||..........|   :|||:..:.|...  :|:||::....:||
 Frog  1174 EPMGCTSTLAV---TSHSLAGSGADAGHSFVVC---LHVDLEPLEIKCSNPQVELLYQLTDTMSK 1232

  Fly  1126 MYGSLCPDEPASKWQTGKMKPRLEVY----TGSAQNYPVIKEFLELDPN-------------FEA 1173
            ::         .|.|...:..:..:|    ||.|...||........|:             .|.
 Frog  1233 VW---------EKIQRRGILHQSSIYCDSSTGPAPGSPVRSSVGTAPPDTSTCSPSADVGTTTEG 1288

  Fly  1174 PKVKSAPKS--------------------SVILFCQWTIPRISFEMENSN-DFKHSKI--VMSLE 1215
            ..:::|..|                    .|.|:.||.:|:|:.::.:.: ..|..||  |..||
 Frog  1289 DSLQAAEDSPFSDSVTLEQTTSNIGVSSGRVSLWMQWMLPKITVKLFSLDPGIKGGKICVVSELE 1353

  Fly  1216 DLLLNIDKHSDFNKITTKIENFGLNYYEEKHEE--WEKIDDLHIKMLGD--------STNLPLIS 1270
            ||..::|....:.|:..|||:|.:::|.....|  |         .||.        :..|...:
 Frog  1354 DLNASVDVQDVYTKVKCKIESFNIDHYRSSFSEDCW---------CLGQYGGVFLSCTDKLNRRT 1409

  Fly  1271 VVITTVSLED-----------------------------LYAKIGARNPHNK------------- 1293
            .::..||.:|                             .|.|...||..:|
 Frog  1410 TLVRPVSKQDPFSNFSGFFPSTTAKLLESSHQQHGFLSLTYTKAVTRNVRHKLTSRSERSPRSFQ 1474

  Fly  1294 ----------QHTISEVLIEVQPIEMVLNLDQITEFMVPICEVLEIIGNSASAQSANKPSAPVPS 1348
                      .|.:.|:||..|..::|:    ....:..:..:.::.......:....|..|:.|
 Frog  1475 KFSEGPADASPHFLHEILISSQAFDIVV----FFPLLNAVSRIFDVRCPPKQKEKRKTPRQPMRS 1535

  Fly  1349 KITTVQDLPMVHLNSKGIYVYLPLSTGKKSCS---------VLLLRIESIQLTPSLENPLVRQLV 1404
            ...|.::||::::::..|.|:.|.:..::..|         .|:::|.|:.:.|..:|||.|.::
 Frog  1536 HALTSRNLPLIYISTSVIRVFFPKAEERQLASGGNQIINEDTLVVKIGSVSMAPQADNPLSRSVL 1600

  Fly  1405 RPDIYQKAAELNMLSTPGALVEDRQYELSVRRVSLSTGNWKQTQEYRIEKT--LASKHD----NP 1463
            |.||||:|..|.:|..||:.||||||::.::.:::.|..|.|.:..:....  |.|:.|    ||
 Frog  1601 RKDIYQRALNLGILRDPGSEVEDRQYQVDLQSINIGTAQWDQLKPEKESNNGGLLSEGDRGTQNP 1665

  Fly  1464 AFEWNNQSQSTELDHME-------IFKDFDFIMIYAPAISYDR-----------FLVCGQSVEYN 1510
            |.|||..|....  |.|       |..|....:..||||.:.:           .||||.|:|.|
 Frog  1666 ALEWNMASNIRR--HQERRALLSPILTDCTVRITAAPAIIFTKMVSPENMQTEDILVCGHSLEVN 1728

  Fly  1511 CATDFVASLNTHQISLISCIIVR--------------------------------------AQRL 1537
            ..|.....|:..|:.|:..::..                                      ||..
 Frog  1729 VTTSLDFFLSVAQVQLLQQLVQENLLGFEETGLEVEVSKQEHQKLDSLDGRTVDTSSRYSGAQDS 1793

  Fly  1538 GCIIDQVCVK--NAELPKARSHKTLGNISKYNS-VDNSIYFPADPKVF----------------K 1583
            |...|.|.::  ..|.....||..:...||.:| |.|..:.|.|  :|                .
 Frog  1794 GIGSDSVKIRIVQVEQQSGASHYRIVRPSKQSSIVKNLNFIPFD--IFITASRISLMSYSCTALA 1856

  Fly  1584 KDTWIPKSSKKLVSERLSYTNASTSFTDAKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLAAEEIN 1648
            |....|...:|:....|:.||     ::|.|..:....:|.|               :|.||:
 Frog  1857 KQKSCPNDGEKIGKSSLNLTN-----SEADGVLEKPGDTCIS---------------TLTAED-- 1899

  Fly  1649 RSGRQPFVLSYPSSVSFVAGIFVLK---------IYDVLELEELERP--------VMKPLFLMTV 1696
                    |..|.||:...|:..|:         ....|.:..:.:|        .:.|...:.:
 Frog  1900 --------LLAPHSVTTRPGLASLERLHATTRSSARQALGITVVRQPGRRGTGDIQLNPFLHLVL 1956

  Fly  1697 SQPSFMSTQNFKAAVTQASIFNVNISVAKADVDGKVDSERFNESVFATLPGQLG----------- 1750
            ||||.:.:.:.:....:.|:|:..:.        .||.|........|||..|.
 Frog  1957 SQPSLLISCHHRKQKLEISMFDALLK--------GVDPEYKCSDAGKTLPEVLDYTRIWLQTVAG 2013

  Fly  1751 ----SSGIPPPLLTIKTQYDRLH-QKEVDVELRKPILLRICENTIKQLASDVFRIYTVLH----- 1805
                .:|||||.:|::.: |.|: ..:|::::.:|:.:.:......|:...:.:|:...|
 Frog  2014 ERNCKTGIPPPFITLQIR-DFLNGPADVNIDISRPLKVNLSFVKFDQVNLFMKKIFLSHHGGSSA 2077

  Fly  1806 ETPCF-NVRSPRPVPEGSQLRQLKMNCYNADRFHLSCDRITAKFYDEERSYKCSFVWLDVSTRIK 1869
            |.... |..:.|..|       ||..........:|.:.:......|:       .|..||...|
 Frog  2078 EAHVIANQTATREEP-------LKPTSRKESGTAVSKESLKKTSLQED-------TWSSVSCLQK 2128

  Fly  1870 FSSRPQKAVIR----------------SNI-GSFYVQSGEKM--LLHPLLMRLSV-DLVSE---- 1910
            .|.|..:.|:.                |:: ||..||:|.|.  .:...|..|.: |.:.:
 Frog  2129 VSFRTTQVVVNLETIPHAQSPCILTSFSDLQGSLSVQAGHKTAETVTSALFHLDINDFIIQTSLN 2193

  Fly  1911 --------PWSEELLVNA-------------TLKLNYLHIDAGVFSILQLQKAQQGVNRIREYAD 1954
                    |.|..:.|.|             |:....:.:..||..:...|:....:..:.|.
 Frog  2194 DRNRNFIGPVSGSVNVEANWCKHSGNPGSPHTIPKILVDVRGGVMQVFWGQENLNCLTLLNEL-- 2256

  Fly  1955 REWQQFLRSRPVLGTPKDVSPCNLIKCTPSHESIE-RIKRPLKSNAEFYQDDLRAGAFQFVYLNS 2018
              :.::|:        || |.|..:...|...|:. .:.||..|..|...||||.|.||::....
 Frog  2257 --FHEYLK--------KD-SRCTAMSNNPPLPSVSPAVGRPQTSKTEHSTDDLRTGFFQYIQDTD 2310

  Fly  2019 ESVLPMPYQVQIIKK---NYGIICWRYPQPRQMTSIHIYPVPMPVSRP-----------IHIRCR 2069
            ...:|..|:|....:   |.|::.||||:||.:|.:.|.|||...:..           :.:.|.
 Frog  2311 AQRVPNAYEVVFYNETEDNPGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDVLQVPCS 2375

  Fly  2070 MEYFSETHETFLHYCDFMLSETSTKQLTPPD--------RPICATIWRVVILQSLISVDGTCFEG 2126
            :||:.|...:|:.:.:|.|||:...:|..|.        ..:.:.:||:|:..|...:|.   :.
 Frog  2376 LEYWDELQRSFVAFREFSLSESKACELQLPSISAVSDQKELVTSDLWRIVLNSSANGIDD---QS 2437

  Fly  2127 SEDEDLSIEYLQSDFKVDENNDFILHPKVLVGCMRIDTVFRAEKVPKLQLLLCCQDIELNFVNQT 2191
            ||.|..|          ..::|.::.|..|..|.|:|:.|.:..||.|.:.:...::||:..:..
 Frog  2438 SESESGS----------QSSSDQLVTPTALAACTRVDSCFTSWLVPSLGVSIQFVNLELHLCHHL 2492

  Fly  2192 DNTGEL-PKQLNKYRLRQTPNITQTFLTVHVEDLQMHSRIYSRNDFS----LQTEMRARVKCLDY 2251
            |:.|.: ||.|:.:...:|......::::..::.|::.|.:|  |.|    :|....|..|.|:.
 Frog  2493 DHLGSVPPKCLHPFVSDKTTPTELEYMSISFKEPQVYLRQWS--DVSVCKEIQFSTEAESKFLEC 2555

  Fly  2252 GFLNMLDVLEPMKFSSYVRLTDYP-RSLVQANFLVDKLRLNCGPHVIHTLLSSKYHWQEVLQQKD 2315
            ..|.|..:::|......:.:||.. ..::....|||.:.:|.|.|.:|::.::...||: .|..:
 Frog  2556 RNLTMKSLVKPFHMQGQMAITDSALEKVLDFTVLVDPIFVNFGQHSVHSINTAILAWQQ-NQCPE 2619

  Fly  2316 VRHVLMPKLVIVNRIQTPISFGQTNTVEKIPVNPGEVQLYHFRSC--SHVQELTFFITNPKTLLV 2378
            ...::....|:.|..|..:.|||.:|.|.|.:    ..|::.:.|  ||        .:|:.|
 Frog  2620 AEELIYSHFVVCNDTQETLRFGQVDTDENIVL----ASLHNHQYCWRSH--------KSPQLL-- 2670

  Fly  2379 DSSDSVHIAL------KFEDEEKIHN----LRVGEY-----CITLKLAKLSTTQIYILVKGQIEL 2428
                  ||.:      ::.:...:.|    :|..:|     .:.:|:.:|:..|..:.:.|:..:
 Frog  2671 ------HICIEGWGNWRWSEPFSVDNAGTFVRTIQYKGRTASLIIKIQQLNGFQKQVTICGRQII 2729

  Fly  2429 VSMVPFNLVTEFREEEINYD-ESTPPEHL--LLSKERSSYYQNVKRNADINMRLKLTAGLGRGRT 2490
            .|.:..::..:..:..|..| ::...||:  |.:|::...|  |..|:::. .|.:.|......:
 Frog  2730 CSYMSESIELKAVQHYIGQDGQAVVREHVDCLTAKQKLPSY--VLENSELT-ELCVKAKGDEAWS 2791

  Fly  2491 GDIPLK---TNNNLPWLVKVPTQSAQQFISIWVRILREDIKMDKPAEDFQPQKILICIWPIFEIC 2552
            .|:.|.   |.:::  :::||: |....|.:|..|:..:     |..  |.|:.:|...|:|.:.
 Frog  2792 QDVCLSSELTEHSM--IIQVPS-SNNSIIYVWCTIISLE-----PGS--QVQQRMIMFSPLFIMR 2846

  Fly  2553 NML--SCAVKATESTTG--ESSTIEAMGGRWALNTATTHATEHNIGFTFSGILRGSSKDEYSLML 2613
            :.|  |..:...:...|  |:..|...|....|..|....|.|   .||    :...:||.|
 Frog  2847 SHLPDSIIIHLEKRNLGLNETQLIPGKGLEKPLQNAEPDLTHH---VTF----QAREEDEPS--- 2901

  Fly  2614 RTMDWHKFFYYDPTVWTIENALHKL-------GKSSKR--------------KWPLNDPEELRVS 2657
                        .....|..:|.|.       |.|:.|              .||.|..:.....
 Frog  2902 ------------ECAVPISTSLIKQIATKAQNGYSANRILSEFYGGESCPQPVWPYNKKDTDSGE 2954

  Fly  2658 RVLDFENAFDVKYQTKATREFSCCQGLDVTAWGMFINGTGLYVAIFMIQEQARLDLKANSLQMMP 2722
            .:..:::...||.........:..  :::..|.:.||.:...:.:|. .|...|.:.|....:.|
 Frog  2955 HLAQWDSPMRVKLSLWKPHLKTLL--VELLPWALLINQSRWDLWLFE-GENIVLQIPAGQTIIPP 3016

  Fly  2723 KLKSAFTIDVRFDNG---WKSSTPICLEDFTQ---KSSSNAGRSLYLRYNSFVDIVI-----VER 2776
            ..:.||.|.:.:.|.   .||.....:.|.|.   |.:.| |..:.|....|||..|     ...
 Frog  3017 NFQEAFQIGIYWANTNTVHKSVAVRLVHDMTSPKWKDADN-GEVVTLDEEGFVDANIKLGAFPGH 3080

  Fly  2777 DEVLRLILEYRQEDDGRRLFKLRSKFVFTNFTDV------VLNALTLAMDHKENSTREEV----- 2830
            .::.:..:. ....:|.::.::..|....|.|.:      .::|:       :.|:.||.
 Frog  3081 QKLCQFCIS-SMVQNGIQILQIEDKTTIINNTSLKVFYSPQISAI-------QQSSEEEYVPVPD 3137

  Fly  2831 -EAYSICKKARSLVSSESTKNCSGNAMDVFYDLNAHKAKHNCDTAFVYF---VCFSVGGSRE--I 2889
             ..:||.....:.::..:...|    .||..|::...|:.:......|.   :|.||||...  .
 Frog  3138 SAVFSINPVGENQIAKPNPIPC----WDVVSDVSQSSAETSPSPLQKYILLSLCPSVGGGNTQCW 3198

  Fly  2890 SIPIPLAVPFTRRCFSLQAGP------ESIPLMITLIEKDNVHYLNVFRDTAPAIVISNNTNVKF 2948
            |:|..:...:.|:..::..|.      .:..:::|..|...:.||.:..|..|.|:|.|...|..
 Frog  3199 SLPAVIRQEYPRQSVAVPVGDCGGSGLCTKAIVLTYQEHLGLTYLTLTEDPCPRIIIRNRCTVAL 3263

  Fly  2949 IVAQT-SASENSNVSCTNSEFVGRNFEWNQLVLP-----HSNCYYTPPQMYANFPDVEFTMCNLS 3007
            ::.:. .......|.|..              :|     |...|:    ..::|||.:..  :|.
 Frog  3264 LLKENIKEMPKFEVYCRR--------------IPAECSLHHELYH----QVSSFPDCKTK--DLL 3308

  Fly  3008 LAVYKDKLCAKNKIAWSKPIRTDKSWQKFLHVPHHGDVKVVVCDKHRAIRLNIYYIAQQLEFSVK 3072
            .::|...|..::         |...|...:.:.:.| .:||....:..:.::|
 Frog  3309 PSIYLKVLSHED---------TATEWSDLIDINNQG-TQVVFLTGYGYVYVDI------------ 3351

  Fly  3073 DLRSRLTKPENVLMPSQEQAAPRPDESSEQENDTKRVTLPNMVT---CAHFNEECESKTQTR-IK 3133
                 :.....|::....:....|..:|...:.::.|.:...:|   ...|::...:||.:. ::
 Frog  3352 -----VQHCGTVIITLAPEGRAGPVLTSLNRSQSQSVMVKFFITQLSLGIFDDVTNAKTSSELLR 3411

  Fly  3134 IFIKSFVFSLQTDNRENDFVKTEVCNIYAD---DSMLIYDDDDDQRELRLQLPNLQVDNQLYSSG 3195
            :.:.:..||:   ...:.:::.....:.||   .|.|.|       .|.:...:||||||||:..
 Frog  3412 LTLDNVFFSV---TPVSSYLRQPCLELQADITCGSTLFY-------SLEMYCGDLQVDNQLYNKS 3466

  Fly  3196 KYDFPVLLCAE------KLYRRNCSLPQVYDLDHVYKQQAQRTPVSLFTFIFYQDE-MQLQNVRC 3253
            .:.||||:|.|      :..:.|.......:|: .:|:.:.   |..|..:..:.| ..|..:..
 Frog  3467 NFHFPVLVCQEERSDSARWAKSNGFQMSTKELE-AFKESSF---VKFFVSLSVEHEAYDLNELSF 3527

  Fly  3254 QIPPFRVYIEDA---YLNQLLEALVECE--PSNCVYSPPVEQDQILLPAGMTLLPDQVVAQSLYI 3313
            ::.|.|:|:||.   |:..|.:..:...  |.:.|..|.        |....|||:||...:|.:
 Frog  3528 EMKPSRLYLEDTFVYYVKTLFDTYLPDSKIPHSAVKFPG--------PKVNHLLPEQVRLYALAL 3584

  Fly  3314 SEPLRLNSFTVEPLNLLLSVHTSSRLYIALDHSPLSFSRYERQQILTVPLRFGQSLGLHYLSGAI 3378
            ..|::|...||:|:|||:|:|.|.:||||.||:|||||.:||..|.|...:...:|.:||.:||:
 Frog  3585 VNPVKLRKLTVQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGAL 3649

  Fly  3379 FGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGLFRGPWGFLVGVTQGSASLLRNVTAGTV 3443
            |.||||||||||||||:.|.||...|:.||..:|.:||.|||..|:.||::|::|.:::::.||:
 Frog  3650 FRAGWVVGSLEILGSPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTSSFVKHISKGTL 3714

  Fly  3444 NSVTKLAGSVARNLDRLTLDAEHIELTEARRRARPQGFADGLTQGLTGLGISLLGAVGGLA---- 3504
            .|:|.||.|:|||:|||:||.||....|..||..|....:||.|||:.||:|||||:.|:.
 Frog  3715 TSLTNLATSLARNMDRLSLDEEHYNRQEEWRRQLPDNLGEGLKQGLSRLGLSLLGAIAGIVDQPM 3779

  Fly  3505 ---HHTLEARSSV-----GVIAGLTKGIVGALTKPISGAAEMLALTGQGVLHTVGFNAMP-QQVE 3560
               ..|.||:.|.     |||:|:.|||||..||||.||||:::.||.|:||..|.:.:| |::.
 Frog  3780 QNFQRTSEAQGSAGHKAKGVISGVGKGIVGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRLL 3844

  Fly  3561 PSFIRNVALHGSSNR-IWSYLPEELSRDQM-LFFSEIMLQISTQLRPALLFLTSSVLAI--MQSD 3621
            |:.:....|..|..: :|..| :.|.|.:: :....:::..|.|.....|.|||.||.:  :..|
 Frog  3845 PTDLPTHQLPNSHVKYVWKML-QSLGRPEVHMALDVVIVSRSGQEYAGCLLLTSEVLFVVSISED 3908

  Fly  3622 SEDLAFASPISKVDVLADREDPSKLYLSLKSE 3653
            ::..||  |:::::.:.|||..:.:.:.||.:
 Frog  3909 TQQQAF--PVTEIECIEDRETANCIKVQLKQQ 3938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13B	NP_651753.2	Chorein_N	5..117	CDD:289396	59/121 (49%)
		VPS13_C	3319..3468	CDD:293514	79/148 (53%)
		ATG_C	3473..3546	CDD:286423	39/84 (46%)
vps13b	XP_002934455.3	Chorein_N	6..>94	CDD:403729	51/87 (59%)
		SHR-BD	<2624..>2708	CDD:399561	20/103 (19%)
		MRS6	<3443..3862	CDD:227376	171/437 (39%)
		VPS13_C	<3615..3736	CDD:407143	63/120 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	368	1.000	Domainoid score	I916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	787	1.000	Inparanoid score	I506
OMA	1	1.010	-	-		QHG46865
OrthoDB	1	1.010	-	-		D51820at33208
OrthoFinder	1	1.000	-	-		FOG0008361
OrthoInspector	1	1.000	-	-		oto105545
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	1	1.000	-	-		X10428
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.100