Protein Alignment eIF2Balpha and GCD2

DIOPT Version :10

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_011597.1
• Gene: GCD2 / 852974
• SGDID: S000003315
• Length: 651
• Species: Saccharomyces cerevisiae
• Alignment Length: 363
• Identity: 85/363 - (23%)
• Similarity: 134/363 - (36%)
• Gaps: 107/363 - (29%)

  Fly    19 QLLDEDKDLSSGIAAIRTLLMILE------KKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAG 77
            |::.:|.....|....|.|...|.      ||    ...|..||..|:..::. ::|:
Yeast   301 QIVIKDYQTPKGTTLSRNLTSYLSHQIDLLKK----ARPLSVTMGNAIRWLKQ-EISL------- 353

  Fly    78 ELFCRFITLSLDDKHMEE--CRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRV 140
                  |..|..||..::  |.:|    |:....|:..:.|:|...|...|.:...|:|:..|:|
Yeast   354 ------IDPSTPDKAAKKDLCEKI----GQFAKEKIELADQLIIDNASTQIEESTTIVTYGSSKV 408

  Fly   141 VLKALI-TASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDC--TLILDSATGYVMESVDFVLV 202
            :.:.|: .|...||:..|.|........|.:|.:.|..||::.  .||....|.:.|: ||:|.:
Yeast   409 LTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRNAGVNVMYALITSLDTIFNMD-VDYVFL 472

  Fly   203 GAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQ---------RDLPN--- 255
            ||.:::.:|.:.:|.||..:.:.|:....|..|..||.|||:...|:.         .||.|
Yeast   473 GAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLDSVTFNELADPNDLVNIDY 537

  Fly   256 -------------------EYKYSRKHL---------------------NDVSK----------- 269
                               |.|:.:|.|                     .|.|.
Yeast   538 ENPVERRGNKGALLNQFIKERKFEKKKLAMENKPKGNKIGGKKGSEGESKDASNEEDSNSKNILD 602

  Fly   270 ----------VHPLVDYTPPVYITLLFTDLGRLTPSAV 297
                      |:.|.|.|||.||..:.|:.|.|.||:|
Yeast   603 GWQELPSLNIVNILYDLTPPEYIKKVITEFGALPPSSV 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:395798	80/347 (23%)
GCD2	NP_011597.1	DUF5585	105..>246	CDD:465521
		IF-2B	285..637	CDD:395798	82/358 (23%)