DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF2Balpha and AT1G53900

DIOPT Version :9

Sequence 1:	NP_651752.1	Gene:	eIF2Balpha / 43549	FlyBaseID:	FBgn0039726	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001322173.1	Gene:	AT1G53900 / 841828	AraportID:	AT1G53900	Length:	604	Species:	Arabidopsis thaliana

Alignment Length:	316	Identity:	128/316 - (40%)
Similarity:	183/316 - (57%)	Gaps:	28/316 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NGQDFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIA 71
            :|:.|.|::.| ....:..||:..:||||.|..::...:..|:..|...:::|...:::.|.:..
plant   301 SGRPFSVIEDF-NSWRQQPDLAEAVAAIRALAAVIRASEATTMMELEIELKKASDTLKSWDTTSI 364

  Fly    72 AIVSAGELFCRFIT----LSLDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRI 132
            ::.:..:||.|::|    |..:|.:..:.|  :|.|.:.|......:|.:||..:|.||.|||.|
plant   365 SLTAGCDLFMRYVTRTSALEFEDFNSAKSR--VLERAEKFGEISCKARTIIAMLSQDFIFDGCTI 427

  Fly   133 LTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESV 197
            |.|..||||.:.|.|::||||.|.|..|:|....:|..:..:|....|...|::|||..|.|:.|
plant   428 LVHGFSRVVFEILKTSAQNKKLFRVLCTEGRPDKTGVLLANELAKLDIPVKLLIDSAVAYSMDEV 492

  Fly   198 DFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDL-----PNEY 257
            |.|.|||:.|||||||||.:|||.:.|.|:.|.||.||.|||:||:|||||:|:||     |.::
plant   493 DMVFVGADGVVESGGIINMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLDQKDLEPALRPIDF 557

  Fly   258 KYSRKHLNDVSKVHPLV-------DYTPPVYITLLFTDLGRLTPSAVSDELIKLYM 306
            ..         .|.|.|       |||||.|:||||||||.||||.||||||:||:
plant   558 SV---------PVPPKVEVERSARDYTPPQYLTLLFTDLGVLTPSVVSDELIQLYL 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:279362	111/279 (40%)
eIF2Balpha	NP_651752.1	GCD2	31..305	CDD:224105	120/289 (42%)
AT1G53900	NP_001322173.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	191	1.000	Domainoid score	I939
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1080
Inparanoid	1	1.050	215	1.000	Inparanoid score	I1226
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D865202at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3009
orthoMCL	1	0.900	-	-		OOG6_102141
Panther	1	1.100	-	-	LDO	PTHR45860
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1674
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830