DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF2Balpha and AT1G53880

DIOPT Version :9

Sequence 1:	NP_651752.1	Gene:	eIF2Balpha / 43549	FlyBaseID:	FBgn0039726	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_564643.3	Gene:	AT1G53880 / 841825	AraportID:	AT1G53880	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	316	Identity:	128/316 - (40%)
Similarity:	183/316 - (57%)	Gaps:	28/316 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NGQDFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIA 71
            :|:.|.|::.| ....:..||:..:||||.|..::...:..|:..|...:::|...:::.|.:..
plant    82 SGRPFSVIEDF-NSWRQQPDLAEAVAAIRALAAVIRASEATTMMELEIELKKASDTLKSWDTTSI 145

  Fly    72 AIVSAGELFCRFIT----LSLDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRI 132
            ::.:..:||.|::|    |..:|.:..:.|  :|.|.:.|......:|.:||..:|.||.|||.|
plant   146 SLTAGCDLFMRYVTRTSALEFEDFNSAKSR--VLERAEKFGEISCKARTIIAMLSQDFIFDGCTI 208

  Fly   133 LTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESV 197
            |.|..||||.:.|.|::||||.|.|..|:|....:|..:..:|....|...|::|||..|.|:.|
plant   209 LVHGFSRVVFEILKTSAQNKKLFRVLCTEGRPDKTGVLLANELAKLDIPVKLLIDSAVAYSMDEV 273

  Fly   198 DFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDL-----PNEY 257
            |.|.|||:.|||||||||.:|||.:.|.|:.|.||.||.|||:||:|||||:|:||     |.::
plant   274 DMVFVGADGVVESGGIINMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLDQKDLEPALRPIDF 338

  Fly   258 KYSRKHLNDVSKVHPLV-------DYTPPVYITLLFTDLGRLTPSAVSDELIKLYM 306
            ..         .|.|.|       |||||.|:||||||||.||||.||||||:||:
plant   339 SV---------PVPPKVEVERSARDYTPPQYLTLLFTDLGVLTPSVVSDELIQLYL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:279362	111/279 (40%)
eIF2Balpha	NP_651752.1	GCD2	31..305	CDD:224105	120/289 (42%)
AT1G53880	NP_564643.3	IF-2B	116..373	CDD:395798	106/267 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	191	1.000	Domainoid score	I939
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1080
Inparanoid	1	1.050	215	1.000	Inparanoid score	I1226
OMA	1	1.010	-	-		QHG54281
OrthoDB	1	1.010	-	-		D865202at2759
OrthoFinder	1	1.000	-	-		FOG0002898
OrthoInspector	1	1.000	-	-		otm3009
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45860
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1674
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.940