Protein Alignment eIF2Balpha and Eif2b2

DIOPT Version :10

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_114447.2
• Gene: Eif2b2 / 84005
• RGDID: 620820
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 73/279 - (26%)
• Similarity: 128/279 - (45%)
• Gaps: 23/279 - (8%)

  Fly    34 IRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLSLDDKHMEECRQ 98
            :|.:|.|: ::::|.:|        ..:...:...|:..::::|.|...|      ..|....:.
  Rat    82 VRRVLKII-REEYGRLH--------GRSDESDQQESLHKLLTSGGLSEDF------SFHYAPLKS 131

  Fly    99 IMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGG 163
            .::......|.:|..:.:.||.||...|.....|:|...||.| :|.:..:..|:.|||...:..
  Rat   132 NIIEAINELLVELEGTTENIAAQALEHIHSNEVIMTIGFSRTV-EAFLREAAQKRKFHVIAAECA 195

  Fly   164 TGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCARE 228
            ....|.||..:|..|||:.|::.|:|...||..|:.|::|.:.::.:|.:....||:|:.|.|:.
  Rat   196 PFCQGHEMAVNLSEAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGSLRAVAGTHTLALAAKH 260

  Fly   229 MKKPFYVLAESFKFSRLYPLNQRDL-----PNE-YKYSRKHLNDVSKVH-PLVDYTPPVYITLLF 286
            ...|..|.|..||.|..:|..:...     |.| ..::...:.:...|| |:.||.||..|||..
  Rat   261 HSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFI 325

  Fly   287 TDLGRLTPSAVSDELIKLY 305
            :::|...||.|...:.:||
  Rat   326 SNIGGNAPSYVYRLMSELY 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:395798	68/266 (26%)
Eif2b2	NP_114447.2	IF-2B	29..333	CDD:395798	68/266 (26%)