Protein Alignment eIF2Balpha and eif2b2

DIOPT Version :10

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001164986.1
• Gene: eif2b2 / 496931
• XenbaseID: XB-GENE-974089
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 85/305 - (27%)
• Similarity: 136/305 - (44%)
• Gaps: 51/305 - (16%)

  Fly    12 DVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSI--AAIV 74
            ::|:..|:|:.|:.....|.:.        |..|..::|.|.|.  |.::...||.|.:  |.::
 Frog    80 NMVRRVLKLIREEYGRLRGCSE--------ENDQQESLHRLITA--ERLSDDFNTPLPLLKANVI 134

  Fly    75 SA-GELFCRFITLSLDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRS 138
            .| .||                            |.:|..:...||.||:..|.....|:|..||
 Frog   135 EAVNEL----------------------------LIELEGTTDNIAIQAKEHIHSNEVIMTIGRS 171

  Fly   139 RVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVG 203
            |.| :..:..:..|::|||.|.:......|.:|...|..|||:.|:|.|:|...||..|:.|::|
 Frog   172 RTV-QLFLEEAARKRTFHVIVAECAPFCQGHDMAASLSKAGIETTVIPDAAIFAVMSRVNKVIIG 235

  Fly   204 AEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRD------LPNE-YKYSR 261
            .:.::.:|.:....||:|:.|.||....|..|.|..||.|..:| |:.|      .|.| ..:|.
 Frog   236 TKTILANGSLRAVSGTHTLALAARHHSTPLIVCAPMFKLSPQFP-NEEDSFHKFVSPQEVLPFSE 299

  Fly   262 -KHLNDVSKVHPLVDYTPPVYITLLFTDLGRLTPSAVSDELIKLY 305
             :.|:.||...|:.|:.||..|||..:::|...||.:...:.:||
 Frog   300 GEILSQVSAYCPIFDHVPPELITLFISNIGGNAPSYIYRLMSELY 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:395798	77/274 (28%)
eif2b2	NP_001164986.1	IF-2B	31..333	CDD:395798	81/292 (28%)