Protein Alignment eIF2Balpha and eIF2Bbeta

DIOPT Version :9

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 76/340 - (22%)
• Similarity: 137/340 - (40%)
• Gaps: 73/340 - (21%)

  Fly    12 DVVKYFLQ-------------LLDEDKDLSSGI------AAIRTLLMILEKKQFGTIHI------ 51
            |:.||.:.             :.|:.|.|.:.:      :.|...::.|.:::|..:|.
  Fly    33 DIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQETVTSNIARRILKLTREEFDLLHAKVQHFA 97

  Fly    52 --------LHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLSLDDKHMEECRQIMLNRGKIFL 108
                    ||..:.:...:..:.|.|:.                     ....|:.:|:..:...
  Fly    98 DDSQASLSLHKLVTQTSESNVSVDYSVP---------------------QHGLREALLDHLQEVE 141

  Fly   109 TKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVK 173
            |:|..|.:.|..||:..|.....|||...||.|...|..|.:.::...:.|.:......|..:..
  Fly   142 TELETSSENICVQAEEHIHSSEIILTLGHSRSVENFLKRAIKKRQFLTIIVAECAPACRGHNLAA 206

  Fly   174 DL-HAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLA 237
            .| :...::..:|.|:|...:|..|:.|::|..:|:.:||:....|.||:.|.|:....|..|||
  Fly   207 SLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSVLANGGLRAACGAYTVALAAKHYSVPVIVLA 271

  Fly   238 ESFKFSRLYPLNQRD-----------LPNEYKYSRKHLNDVSKVH-PLVDYTPPVYITLLFTDLG 290
            ..:|.|.|: |.::|           :|.:...:|:     :||: |:.||.||..:||..::.|
  Fly   272 PMYKLSPLH-LCEQDAFNMVGCAEDVIPYDSIPARE-----AKVYSPMFDYVPPELVTLFISNTG 330

  Fly   291 RLTPSAVSDELIKLY 305
            ...||.|...|.:||
  Fly   331 GHAPSYVYRLLTELY 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:279362	64/296 (22%)
		GCD2	31..305	CDD:224105	68/306 (22%)
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	74/338 (22%)
		IF-2B	21..334	CDD:279362	70/327 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451047
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1184
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740