Protein Alignment eIF2Balpha and tif224

DIOPT Version :10

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_594503.1
• Gene: tif224 / 2542064
• PomBaseID: SPAC21E11.06
• Length: 467
• Species: Schizosaccharomyces pombe
• Alignment Length: 312
• Identity: 87/312 - (27%)
• Similarity: 142/312 - (45%)
• Gaps: 47/312 - (15%)

  Fly    31 IAAIRTLLMILEKKQ--FGTIHILHTT--MREAVAAMRNT-DLSIAAIVSAGELFCRFITLSLD- 89
            |..::|..::::..|  :||....|.|  :...:|.:.:| .|||    |.|... ||:.|.:.
pombe   165 IDLLKTFKIVIQDYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSI----SMGNAI-RFLKLEISV 224

  Fly    90 ---DKHMEECRQIMLNRGKIFL-TKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQ 150
               |...:|.::::|.:...:: .:::.:.|||.|.|...|.||..|||:..|..|...||.|..
pombe   225 LDIDLTDDEGKELLLEKIDSYIRDRIIIAGQVIVQAATEKIQDGDVILTYLHSSTVNDVLIHAKN 289

  Fly   151 NKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIIN 215
            ..|.|.|.|........|...:|.|...||:||.::.||..|:|:.|..:.:|..|::.:|.:.:
pombe   290 VGKKFRVVVVDSRPEFEGRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSNGALYS 354

  Fly   216 RIGTYTMGLCAREMKKPFYVLAESFKF-----------SRLYPLNQ---------RDLPN---EY 257
            |.||..:.|...|...|.....||:||           :.|.|.:|         .:.|.   .:
pombe   355 RAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFEEKPGVLANW 419

  Fly   258 KYSRKHLNDVSKVHPLVDYTPPVYITLLFTDLGRLTPS----AVSDELIKLY 305
            | |.|:|..:|..:   |.|||..||:...::| |.||    |:.:|..::|
pombe   420 K-SVKNLKLLSLKY---DVTPPRLITVCVCEMG-LLPSTSVPAIINEFKQVY 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:395798	82/295 (28%)
tif224	NP_594503.1	IF-2B	156..451	CDD:395798	82/295 (28%)