Protein Alignment eIF2Balpha and SPCC11E10.07c

DIOPT Version :9

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_588203.1
• Gene: SPCC11E10.07c / 2539154
• PomBaseID: SPCC11E10.07c
• Length: 341
• Species: Schizosaccharomyces pombe
• Alignment Length: 338
• Identity: 125/338 - (36%)
• Similarity: 185/338 - (54%)
• Gaps: 53/338 - (15%)

  Fly    10 DFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTI----HILH---TTMREAVAAMRNTD 67
            :||:|:.:.:.|.:|.:::..:|||..|:.:|.:.|..||    .||.   .|::|.|    ..:
pombe    16 EFDIVQVYKKFLQDDPEITMPVAAIEALVQLLSRSQAKTISEFMDILQNGSNTLKEGV----QNN 76

  Fly    68 LSIAAIVSAG-ELFCRFITLSLDD-KHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGC 130
            :|:    ||| ::|.||:|.||.| ...|:|::.::..||:|:.:....||.||......|.||.
pombe    77 ISL----SAGCDIFQRFVTRSLHDVGDFEQCKRHLVENGKLFIQRARACRQRIAHLGYPLIRDGS 137

  Fly   131 RILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVME 195
            .||||..||.|...|:.|::....|.|:||:.....||..|.:.|..|.|...::||||..:.|.
pombe   138 VILTHGFSRGVAAVLLAAAKRHVRFKVFVTESRPSGSGCLMTRTLKNACIPTCMVLDSAVSFTMN 202

  Fly   196 SVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDLPNEYKYS 260
            .||.||||||.|||:||:||:|||:.:.:.|:...||||.:|||.||.|::||:|.|:|    :|
pombe   203 RVDLVLVGAEGVVENGGLINQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIP----FS 263

  Fly   261 RKHL--NDVS--KVH---------------------------PLVDYTPPVYITLLFTDLGRL-T 293
            |..|  :|.|  .||                           |.:|.|||.:::.|.||||.: :
pombe   264 RPILEFDDPSPETVHPEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVSGLITDLGIIDS 328

  Fly   294 PSAVSDELIKLYM 306
            .|.||:||||||:
pombe   329 KSGVSEELIKLYL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:279362	111/304 (37%)
		GCD2	31..305	CDD:224105	118/314 (38%)
SPCC11E10.07c	NP_588203.1	GCD2	12..341	CDD:224105	124/336 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	156	1.000	Domainoid score	I1051
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1080
Inparanoid	1	1.050	181	1.000	Inparanoid score	I1116
OMA	1	1.010	-	-		QHG54281
OrthoFinder	1	1.000	-	-		FOG0002898
OrthoInspector	1	1.000	-	-		oto100895
orthoMCL	1	0.900	-	-		OOG6_102141
Panther	1	1.100	-	-	LDO	PTHR45860
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R371
SonicParanoid	1	1.000	-	-		X1674
TreeFam	1	0.960	-	-
	14	13.860