DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF2Balpha and Eif2b2

DIOPT Version :9

Sequence 1:NP_651752.1 Gene:eIF2Balpha / 43549 FlyBaseID:FBgn0039726 Length:306 Species:Drosophila melanogaster
Sequence 2:NP_663420.1 Gene:Eif2b2 / 217715 MGIID:2145118 Length:351 Species:Mus musculus


Alignment Length:279 Identity:72/279 - (25%)
Similarity:128/279 - (45%) Gaps:23/279 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 IRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLSLDDKHMEECRQ 98
            :|.:|.|: ::::|.:|        ..:...:...|:..::::|.|...|      ..|....:.
Mouse    82 VRRVLKII-REEYGRLH--------GRSDESDQQESLHKLLTSGGLSEDF------SFHFAPLKA 131

  Fly    99 IMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGG 163
            .::......|.:|..:.:.||.||...|.....|:|...||.| :|.:..:..|:.|||.|.:..
Mouse   132 NIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGYSRTV-EAFLKEAARKRKFHVIVAECA 195

  Fly   164 TGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCARE 228
            ....|.||..:|...||:.|::.|:|...||..|:.|::|.:.::.:|.:....||:|:.|.|:.
Mouse   196 PFCQGHEMAVNLSKEGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGSLRAVAGTHTLALAAKH 260

  Fly   229 MKKPFYVLAESFKFSRLYPLNQRDL-----PNE-YKYSRKHLNDVSKVH-PLVDYTPPVYITLLF 286
            ...|..|.|..||.|..:|..:...     |.| ..::...:.:...|| |:.||.||..|||..
Mouse   261 HSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFI 325

  Fly   287 TDLGRLTPSAVSDELIKLY 305
            :::|...||.:...:.:||
Mouse   326 SNIGGNAPSYIYRLMSELY 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF2BalphaNP_651752.1 IF-2B 30..294 CDD:279362 68/266 (26%)
GCD2 31..305 CDD:224105 70/277 (25%)
Eif2b2NP_663420.1 IF-2B 28..333 CDD:279362 68/266 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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