Protein Alignment eIF2Balpha and eif-2Bdelta

DIOPT Version :10

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001023784.1
• Gene: eif-2Bdelta / 179331
• WormBaseID: WBGene00008670
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 62/317 - (19%)
• Similarity: 109/317 - (34%)
• Gaps: 97/317 - (30%)

  Fly     1 MPQITENGQDFDVVKYFLQLL----DEDKDLSSGI--AAIRTL-------------LMILEKKQF 46
            ||.:.    .||:.|...:.|    |.|:.::|.|  .||..|             |.::.|.:.
 Worm   181 MPSVV----TFDLPKNQTKTLPSASDSDEAVASEIESTAIAQLDDATSFVHIHPAFLTLMAKAEL 241

  Fly    47 GTIHILHTTMREAVAAMR----------------------NTDLSIA----------------AI 73
            ..|..:.|...:.:||.:                      :.||:|.                |:
 Worm   242 EKIPDVETVCIQFIAAFKEFLRDWTVEREKNNINASTFGHDLDLAIRPQLAHMTQNGHWPLPFAL 306

  Fly    74 VSAGELFCRFITLSLDDKHMEE-----CRQIMLNRGKIFL--TKLLN-------SRQVIAQQAQR 124
            .:...|..|.|      |.:||     |.:.:    :::|  |..:|       ..|::.::.|:
 Worm   307 GNTVRLLKRTI------KRLEESTNMKCEEEL----QVYLEDTLAINFCHAYKAISQLLVRKIQQ 361

  Fly   125 F----ITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLI 185
            |    :.|.|.::.|        .|:.|.|......:.|....:...|...||.....|.:...:
 Worm   362 FKKVVVFDWCPVVNH--------VLLEAKQQIPDMQLSVIDANSNGRGTRHVKSFVDQGYNVKYV 418

  Fly   186 LDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKF 242
            ......:...:...:::|..|:..:|.:..|.|...:.|||.....|..|:||.|||
 Worm   419 TMKGASWASLASGVLILGCSAIFANGAVAARKGALAVVLCANHYNIPVIVVAEHFKF 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:395798	53/284 (19%)
eif-2Bdelta	NP_001023784.1	IF-2B	301..513	CDD:395798	40/193 (21%)