Protein Alignment eIF2Balpha and eif-2Balpha

DIOPT Version :9

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_499106.1
• Gene: eif-2Balpha / 176348
• WormBaseID: WBGene00014221
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 300
• Identity: 117/300 - (39%)
• Similarity: 180/300 - (60%)
• Gaps: 6/300 - (2%)

  Fly    13 VVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAG 77
            ::..|...|:.|...|:.:|.:.|||.:|::.:..|:......:.:.|||:..||.|..:|.||.
 Worm     6 IISSFRGKLENDPSKSTSLATVETLLEVLDRSRATTVAEFQNELNQVVAALEKTDYSSTSIRSAA 70

  Fly    78 ELFCRFITLS----LDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRS 138
            :||.||.:|:    ||.:...:...:...|.:.|:..:..||..|::.|:.|.|....|||||.|
 Worm    71 DLFTRFTSLAPAALLDQEDFSQVLDLYRQRARSFIKNVRGSRAKISKCARLFFTHHMNILTHSYS 135

  Fly   139 RVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVG 203
            :|||:.::.|.::....||:||:.....||:.:.::|...|:..||:|||..|||||.:..||||
 Worm   136 KVVLETILDAHKSGYHLHVWVTESQPDASGKLVFEELKKNGVPTTLVLDSCVGYVMERIQAVLVG 200

  Fly   204 AEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDLPNEYKYSRKHL--ND 266
            ||.|:|:|||||:|||..:.:.|:....|.||.||:.||.|.:||||.|:|.|:||....:  |:
 Worm   201 AEGVMETGGIINKIGTVNVCIIAKSRHVPVYVCAETIKFVREFPLNQADIPQEFKYRTSVIERNN 265

  Fly   267 VSKVHPLVDYTPPVYITLLFTDLGRLTPSAVSDELIKLYM 306
            :...||.||||.|.::||:.||:|.:.|.||.:||||:|:
 Worm   266 LELEHPDVDYTAPEFLTLIITDVGAMKPEAVGEELIKMYI 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:279362	105/269 (39%)
		GCD2	31..305	CDD:224105	112/279 (40%)
eif-2Balpha	NP_499106.1	GCD2	1..304	CDD:224105	116/297 (39%)
		IF-2B	15..293	CDD:279362	107/277 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167610
Domainoid	1	1.000	196	1.000	Domainoid score	I1824
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1080
Inparanoid	1	1.050	217	1.000	Inparanoid score	I2310
Isobase	1	0.950	-	0	Normalized mean entropy	S860
OMA	1	1.010	-	-		QHG54281
OrthoDB	1	1.010	-	-		D572463at33208
OrthoFinder	1	1.000	-	-		FOG0002898
OrthoInspector	1	1.000	-	-		oto17685
orthoMCL	1	0.900	-	-		OOG6_102141
Panther	1	1.100	-	-	LDO	PTHR45860
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R371
SonicParanoid	1	1.000	-	-		X1674
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750