Protein Alignment eIF2Balpha and Eif2b4

DIOPT Version :10

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001120827.1
• Gene: Eif2b4 / 13667
• MGIID: 95300
• Length: 544
• Species: Mus musculus
• Alignment Length: 248
• Identity: 69/248 - (27%)
• Similarity: 118/248 - (47%)
• Gaps: 27/248 - (10%)

  Fly    71 AAIVSAGELFCRFITLSLDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQA-QRF----ITDGC 130
            |::.:|.:...:.:|.....|..||.:..:    :..|.:.:..:.|:|.|| .||    |:||.
Mouse   292 ASMCNAIKFLTKEVTGMSSSKREEEAKSEL----REALDRYVQEKIVLAAQAISRFASTKISDGD 352

  Fly   131 RILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVME 195
            .||.:..|.:|.:.|..|....:.|.|.|........|..|:..|..||:..:.:|..|..||:.
Mouse   353 VILVYGCSSLVSRILQEARVEGRRFRVVVVDSRPRLEGRHMLHSLVRAGVPTSYLLIPAASYVLP 417

  Fly   196 SVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKF-----SRLYPLNQRDLPN 255
            .|..||:||.|::.:|.:::|:||..:.|.||....|..|..|::||     :..:..|:.|.|:
Mouse   418 EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPD 482

  Fly   256 EYKYSRKHLNDVS----KVHP-------LVDYTPPVYITLLFTDLGRLTPSAV 297
            :.:..|.  :.|:    :.||       :.|.|||..:.|:.|:||.:..|:|
Mouse   483 DLQCKRG--DQVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSV 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:395798	67/243 (28%)
Eif2b4	NP_001120827.1	IF-2B	240..530	CDD:395798	67/243 (28%)