Protein Alignment eIF2Balpha and Eif2b4

DIOPT Version :9

• Sequence 1: NP_651752.1
• Gene: eIF2Balpha / 43549
• FlyBaseID: FBgn0039726
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: XP_038967625.1
• Gene: Eif2b4 / 117019
• RGDID: 620208
• Length: 544
• Species: Rattus norvegicus
• Alignment Length: 242
• Identity: 64/242 - (26%)
• Similarity: 118/242 - (48%)
• Gaps: 15/242 - (6%)

  Fly    71 AAIVSAGELFCRFITLSLDDKHMEECRQIMLNR-GKIFLTKLLNSRQVIAQQAQRFITDGCRILT 134
            |::.:|.:.|.:.:|.....|..||.:..:... .:....|::.:.|.|::.|.:.|:||..||.
  Rat   292 ASMCNAIKFFNKEVTGMSSSKREEEAKSELKEAIDRYVQEKIVLASQAISRFASKKISDGDVILV 356

  Fly   135 HSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDF 199
            :..|.:|.:.|..|....:.|.|.|........|..|:..|..||:..:.:|..|..||:..|..
  Rat   357 YGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRHMLHCLVRAGVPTSYLLIPAASYVLPEVSK 421

  Fly   200 VLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKF-----SRLYPLNQRDLPNEYKY 259
            ||:||.|::.:|.:::|:||..:.|.||....|..|..|::||     :..:..|:.|.|::.:.
  Rat   422 VLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQC 486

  Fly   260 SR---------KHLNDVSKVHPLVDYTPPVYITLLFTDLGRLTPSAV 297
            .|         ::.:.:..::.:.|.|||..:.|:.|:||.:..|:|
  Rat   487 KRGDQVTLANWQNNSSLRLLNLVYDVTPPELVDLVITELGMIPCSSV 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Balpha	NP_651752.1	IF-2B	30..294	CDD:279362	62/237 (26%)
		GCD2	31..305	CDD:224105	64/242 (26%)
Eif2b4	XP_038967625.1	IF-2B	240..530	CDD:395798	62/237 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810