Protein Alignment Jon99Ci and PRSS2

DIOPT Version :10

• Sequence 1: NP_524555.1
• Gene: Jon99Ci / 43545
• FlyBaseID: FBgn0003358
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 94/281 - (33%)
• Similarity: 136/281 - (48%)
• Gaps: 49/281 - (17%)

  Fly     6 LLSLAFLGVCSALTVPHSLVHPRDLEIRHGGIEGRITNGNLASEGQVPYIVGVSLNSNGNWWWCG 70
            ||.|.|  |.:|:..|..             .:.:|..|.:..|..|||  .|||||  .:.:||
Human     4 LLILTF--VAAAVAAPFD-------------DDDKIVGGYICEENSVPY--QVSLNS--GYHFCG 49

  Fly    71 GSIIGHTWVLTAAHCTAGADEASLYYGAVNYNEPAFR---HTV----SSENF------IRYPHYV 122
            ||:|...||::|.||...|..:.|......|:....|   |.:    .:|.|      ||:|.|.
Human    50 GSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYN 114

  Fly   123 G--LDHDLALIK--TPHVDFYSLVNKIELPSLDDRYNSYENNWVQAAGWG-AIYDGSNVVEDLRV 182
            .  ||:|:.|||  :|.| ..|.|:.|.||:......:..    ..:||| .:..|::..::|:.
Human   115 SRTLDNDILLIKLSSPAV-INSRVSAISLPTAPPAAGTES----LISGWGNTLSSGADYPDELQC 174

  Fly   183 VDLKVISVAECQAYYGTDTASENTICVE-TPDGKATCQGDSGGPLVTKEGDKLIGITSFVSAYGC 246
            :|..|:|.|||:|.| ....:.|..||. ...||.:||||||||:|:  ..:|.||.|:  .|||
Human   175 LDAPVLSQAECEASY-PGKITNNMFCVGFLEGGKDSCQGDSGGPVVS--NGELQGIVSW--GYGC 234

  Fly   247 -QVGGPAGFTRVTKYLEWIKE 266
             |...|..:|:|..|::|||:
Human   235 AQKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Ci	NP_524555.1	Tryp_SPc	41..266	CDD:238113	86/244 (35%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	87/246 (35%)