Protein Alignment Jon99Ci and PRSS1

DIOPT Version :10

• Sequence 1: NP_524555.1
• Gene: Jon99Ci / 43545
• FlyBaseID: FBgn0003358
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 87/271 - (32%)
• Similarity: 127/271 - (46%)
• Gaps: 45/271 - (16%)

  Fly     6 LLSLAFLGVCSALTVPHSLVHPRDLEIRHGGIEGRITNGNLASEGQVPYIVGVSLNSNGNWWWCG 70
            ||.|.|  |.:||..|..             .:.:|..|....|..|||  .|||||  .:.:||
Human     4 LLILTF--VAAALAAPFD-------------DDDKIVGGYNCEENSVPY--QVSLNS--GYHFCG 49

  Fly    71 GSIIGHTWVLTAAHCTAGADEASLYYGAVNY-----NEPAFRHTVSSENFIRYPHY--VGLDHDL 128
            ||:|...||::|.||.....:..|  |..|.     ||    ..:::...||:|.|  ..|::|:
Human    50 GSLINEQWVVSAGHCYKSRIQVRL--GEHNIEVLEGNE----QFINAAKIIRHPQYDRKTLNNDI 108

  Fly   129 ALIK-TPHVDFYSLVNKIELPSLDDRYNSYENNWVQAAGWG-AIYDGSNVVEDLRVVDLKVISVA 191
            .||| :......:.|:.|.||:......:.    ...:||| ....|::..::|:.:|..|:|.|
Human   109 MLIKLSSRAVINARVSTISLPTAPPATGTK----CLISGWGNTASSGADYPDELQCLDAPVLSQA 169

  Fly   192 ECQAYYGTDTASENTICVE-TPDGKATCQGDSGGPLVTKEGDKLIGITSFVSAYGC-QVGGPAGF 254
            :|:|.|.....| |..||. ...||.:||||||||:|.  ..:|.|:.|:  ..|| |...|..:
Human   170 KCEASYPGKITS-NMFCVGFLEGGKDSCQGDSGGPVVC--NGQLQGVVSW--GDGCAQKNKPGVY 229

  Fly   255 TRVTKYLEWIK 265
            |:|..|::|||
Human   230 TKVYNYVKWIK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Ci	NP_524555.1	Tryp_SPc	41..266	CDD:238113	79/236 (33%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	76/234 (32%)