DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon99Cii and Prss8

DIOPT Version :9

Sequence 1:	NP_524554.1	Gene:	Jon99Cii / 43544	FlyBaseID:	FBgn0003356	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_579929.1	Gene:	Prss8 / 76560	MGIID:	1923810	Length:	339	Species:	Mus musculus

Alignment Length:	248	Identity:	79/248 - (31%)
Similarity:	116/248 - (46%)	Gaps:	29/248 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 IQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGNTWVLTAAHC---TNGASGVTINYGA- 92
            ||.|||.|..|..|:.|:.|.:.:  :||..||||::.|.||::||||   .:......:..||
Mouse    41 IQPRITGGGSAKPGQWPWQVSITY--DGNHVCGGSLVSNKWVVSAAHCFPREHSREAYEVKLGAH 103

  Fly    93 --SIRTQPQYTHWVGSGDIIQHHHYNSGNLHNDISLIR-TPHVDFWSLVNKVELPSYNDRYQDYA 154
              ...:.....|.|  ..||.|..|.......||:||| :..|.|...:..:.||:.|..:.:
Mouse   104 QLDSYSNDTVVHTV--AQIITHSSYREEGSQGDIALIRLSSPVTFSRYIRPICLPAANASFPN-- 164

  Fly   155 GWWAVASGWGGTYDGSPL--PDWLQSVDVQIISQSDCSRTWSLH----------DNMICIN-TDG 206
            |.....:|||.......|  |..||.::|.:||:..||..::::          .:|:|.. ..|
Mouse   165 GLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAVPEEPHTIQQDMLCAGYVKG 229

  Fly   207 GKSTCGGDSGGPL-VTHDGN-RLVGVTSFGSAAGCQSGAPAVFSRVTGYLDWI 257
            ||..|.||||||| ...:|. .|.|:.|:|.|.|..: .|.|::..:.|..||
Mouse   230 GKDACQGDSGGPLSCPMEGIWYLAGIVSWGDACGAPN-RPGVYTLTSTYASWI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	76/244 (31%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	76/244 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910