Protein Alignment Jon99Cii and KLK7

DIOPT Version :10

• Sequence 1: NP_524554.1
• Gene: Jon99Cii / 43544
• FlyBaseID: FBgn0003356
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 89/274 - (32%)
• Similarity: 124/274 - (45%)
• Gaps: 59/274 - (21%)

  Fly     7 LALAVAAATAVPAPAQKLTPTPIKDIQG-RITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGN 70
            |.|::|..||.            ::.|| :|.:|.|...|..|:.|.|| ||| ...|||.::..
Human    12 LLLSLALETAG------------EEAQGDKIIDGAPCARGSHPWQVALL-SGN-QLHCGGVLVNE 62

  Fly    71 TWVLTAAHCTNGASGVTINYGASIRTQPQYTHWVGS---GD----------IIQHHHYNSGNLHN 122
            .||||||||                ...:||..:||   ||          ..:|..|::....|
Human    63 RWVLTAAHC----------------KMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVN 111

  Fly   123 DISLIR-TPHVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSP---LPDWLQSVDVQI 183
            |:.|:: .......|:|.||.|||..:.    .|.....||||.|  .||   .|..|..|||::
Human   112 DLMLVKLNSQARLSSMVKKVRLPSRCEP----PGTTCTVSGWGTT--TSPDVTFPSDLMCVDVKL 170

  Fly   184 ISQSDCSRTWS--LHDNMICIN-TDGGKSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGCQSGAPA 245
            ||..||::.:.  |.::|:|.. .|..|:.|.||||||||..  ..|.|:.|:|:....|...|.
Human   171 ISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCR--GTLQGLVSWGTFPCGQPNDPG 233

  Fly   246 VFSRVTGYLDWIRD 259
            |:::|..:..||.|
Human   234 VYTQVCKFTKWIND 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	82/244 (34%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	79/241 (33%)