Protein Alignment Jon99Cii and PRSS2

DIOPT Version :10

• Sequence 1: NP_524554.1
• Gene: Jon99Cii / 43544
• FlyBaseID: FBgn0003356
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 98/279 - (35%)
• Similarity: 142/279 - (50%)
• Gaps: 44/279 - (15%)

  Fly     1 MKLFVFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGG 65
            |.|.:.|.. ||||.|.|.           |...:|..||...|..|||.|.|   .:|..:|||
Human     1 MNLLLILTF-VAAAVAAPF-----------DDDDKIVGGYICEENSVPYQVSL---NSGYHFCGG 50

  Fly    66 SIIGNTWVLTAAHCTNGA-----SG-------VTINYGA-SIRTQPQYTHWVGSGDIIQHHHYNS 117
            |:|...||::|.||...|     ||       :.:..|. :|........::.:..||:|..|||
Human    51 SLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNS 115

  Fly   118 GNLHNDISLIR--TPHVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTY-DGSPLPDWLQSV 179
            ..|.|||.||:  :|.| ..|.|:.:.||:    ....||..::.||||.|. .|:..||.||.:
Human   116 RTLDNDILLIKLSSPAV-INSRVSAISLPT----APPAAGTESLISGWGNTLSSGADYPDELQCL 175

  Fly   180 DVQIISQSDCSRTW--SLHDNMICIN-TDGGKSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGC-Q 240
            |..::||::|..::  .:.:||.|:. .:|||.:|.||||||:|::  ..|.|:.|:|  .|| |
Human   176 DAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSN--GELQGIVSWG--YGCAQ 236

  Fly   241 SGAPAVFSRVTGYLDWIRD 259
            ...|.|:::|..|:|||:|
Human   237 KNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	88/244 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	88/244 (36%)