DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon99Cii and prss27

DIOPT Version :9

Sequence 1:	NP_524554.1	Gene:	Jon99Cii / 43544	FlyBaseID:	FBgn0003356	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	287	Identity:	95/287 - (33%)
Similarity:	131/287 - (45%)	Gaps:	68/287 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LTP-----TP------IKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGNTWVLTAA 77
            |||     ||      |..:..||..|..|.||:.|:.|.  |..||..:|||::|...:|::||
Frog    11 LTPGLLGITPGATDCGIPLVSSRIMGGQSAQEGQWPWQVS--FRNNGGHFCGGTLISKQYVISAA 73

  Fly    78 HC---TNGASGVTINYGASIRTQP-------------QYTHWVGSGDIIQHHHYNSGNLHNDISL 126
            ||   ::.||.||...||.:..||             .|..:|..||        ||    ||||
Frog    74 HCFPSSSSASSVTAVLGAYMIDQPDGNQVAIPVQSATNYPSYVNEGD--------SG----DISL 126

  Fly   127 IR--TPHVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSPL--PDWLQSVDVQIISQS 187
            ::  :| |.|.:.:..|.||:....:......|  .:|||.......|  |..||.|.|.:|..:
Frog   127 VQLASP-VTFTNYILPVCLPADTVTFPTGLQCW--VTGWGNIASDVSLVSPMTLQEVAVPLIDAN 188

  Fly   188 DCSRTW-----------SLHDNMICIN-TDGGKSTCGGDSGGPLVTHDGNR--LVGVTSFGSAAG 238
            :|:..:           |:|.:|||.. .:|||.:|.||||||||.....:  |.||.|||...|
Frog   189 ECNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSSSGQWFLAGVVSFGEGCG 253

  Fly   239 CQSGAPAVFSRVTGYLDWIRDNTGISY 265
             |:..|.|::.:..|.|||     :||
Frog   254 -QAYRPGVYTLMPSYTDWI-----VSY 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	86/257 (33%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	84/254 (33%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910