Protein Alignment Jon99Cii and KLK14

DIOPT Version :10

• Sequence 1: NP_524554.1
• Gene: Jon99Cii / 43544
• FlyBaseID: FBgn0003356
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 69/274 - (25%)
• Similarity: 111/274 - (40%)
• Gaps: 47/274 - (17%)

  Fly     5 VFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIG 69
            :||.|......|:       ..|..::.:.:|..|:.......|:...||......:.|||:::.
Human     1 MFLLLTALQVLAI-------AMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 58

  Fly    70 NTWVLTAAHCTNGASGVTINYGASIRTQPQYTHWVGSGDIIQ------HHHYNSGNLHNDISLIR 128
            ..||:|||||......|.:.       :.....|..:..:::      |.:|||....||:.|::
Human    59 GQWVITAAHCGRPILQVALG-------KHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQ 116

  Fly   129 TPH-VDFWSLVNKVEL------PSYNDRYQDYAGWWAVASGWGGTYDGSPL---PDWLQSVDVQI 183
            ... ......|..:|:      |..:.|          .||||..  .||:   |..||.|::.|
Human   117 LQQPARIGRAVRPIEVTQACASPGTSCR----------VSGWGTI--SSPIARYPASLQCVNINI 169

  Fly   184 ISQSDCSRTW--SLHDNMICINT-DGGKSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGCQSGAPA 245
            .....|.:.:  ::...|:|... .|||.:|.||||||||..  .:|.|:.|:|.......|.|.
Human   170 SPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCR--GQLQGLVSWGMERCALPGYPG 232

  Fly   246 VFSRVTGYLDWIRD 259
            |::.:..|..||.:
Human   233 VYTNLCKYRSWIEE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	64/243 (26%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	64/243 (26%)