Protein Alignment Jon99Cii and KLK1

DIOPT Version :10

• Sequence 1: NP_524554.1
• Gene: Jon99Cii / 43544
• FlyBaseID: FBgn0003356
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 87/289 - (30%)
• Similarity: 121/289 - (41%)
• Gaps: 68/289 - (23%)

  Fly     4 FVFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLL-FSGNGNWWCGGSI 67
            |:.|.||::......||          .||.||..|:...:...|:...|. ||   .:.|||.:
Human     3 FLVLCLALSLGGTGAAP----------PIQSRIVGGWECEQHSQPWQAALYHFS---TFQCGGIL 54

  Fly    68 IGNTWVLTAAHCTNGASGVTINYGASIRTQPQYTHWVGSGDIIQ---------------HHHYNS 117
            :...||||||||.:                ..|..|:|..::..               |..:|.
Human    55 VHRQWVLTAAHCIS----------------DNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNM 103

  Fly   118 GNLHN-----------DISLIR--TPHVDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTY-D 168
            ..|.|           |:.|:|  .|.......|..||||:    .:...|...:|||||... :
Human   104 SLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT----EEPEVGSTCLASGWGSIEPE 164

  Fly   169 GSPLPDWLQSVDVQIISQSDCSR--TWSLHDNMICI-NTDGGKSTCGGDSGGPLVTHDGNRLVGV 230
            ....||.||.||::|:...:|.:  ...:.|.|:|: :.:|||.||.|||||||:. || .|.||
Human   165 NFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMC-DG-VLQGV 227

  Fly   231 TSFGSAAGCQSGAPAVFSRVTGYLDWIRD 259
            ||:|.........|:|..||..|:.||.|
Human   228 TSWGYVPCGTPNKPSVAVRVLSYVKWIED 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	78/257 (30%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	78/257 (30%)