DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon99Cii and C1s2

DIOPT Version :9

Sequence 1:	NP_524554.1	Gene:	Jon99Cii / 43544	FlyBaseID:	FBgn0003356	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	273	Identity:	75/273 - (27%)
Similarity:	111/273 - (40%)	Gaps:	52/273 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGNTWVLTAAHCTNGAS------ 84
            ||....:|.:|..|.||.....|:.|   |..:..  .||::|...|||||||.....|
Mouse   434 PTEPFQVQQKIFGGQPAKIENFPWQV---FFNHPT--AGGALINEYWVLTAAHVVEKNSDPSMYA 493

  Fly    85 GVTINYGASI-RTQPQYTH-------WVGSGDIIQHHHYNSGNLHNDISLIRTPH-VDFWSLVNK 140
            |:|....|.: ..|..||.       |....|:...     .|..|||:|::... |......:.
Mouse   494 GITALRLADLENAQRLYTKRVIIHPGWKEDDDLNPR-----TNFDNDIALVQLKDPVKMGPKFSP 553

  Fly   141 VELPSYNDRYQDYAGWWAVASGWGGTYDGSPLPDWLQSVDVQIISQSDCSRT-----------WS 194
            :.||..:..|....|...:.||||.|.....:.: |:...|.:.|...|.:.           :.
Mouse   554 ICLPGTSSEYNLSPGDMGLISGWGRTEKRLHVIN-LRGAKVPVTSLETCKQVKEENPTARPEDYV 617

  Fly   195 LHDNMICINTDGGKSTCGGDSGG------PLVTHDGNRLVGVTSFGSAAGCQSGAPAVFSRVTGY 253
            :.|||||.. :.|..:|.|||||      |.|......:.|:.|:|.    :.||..|:::|..|
Mouse   618 ITDNMICAG-EKGVDSCKGDSGGAFAFQVPNVKAPKFYVAGLVSWGK----KCGAYGVYTKVKNY 677

  Fly   254 LDWI----RDNTG 262
            :|||    ::|:|
Mouse   678 VDWILKTMQENSG 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	70/259 (27%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	68/253 (27%)
		Tryp_SPc	444..684	CDD:238113	70/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910