DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trp and Xndc1

DIOPT Version :9

Sequence 1:	NP_476768.1	Gene:	trp / 43542	FlyBaseID:	FBgn0003861	Length:	1275	Species:	Drosophila melanogaster
Sequence 2:	NP_001316819.1	Gene:	Xndc1 / 102549471	RGDID:	7692537	Length:	407	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	50/278 - (17%)
Similarity:	89/278 - (32%)	Gaps:	79/278 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   867 SDPIGSKRSSMQRHSQRSLRRKIIEQANEGLQMNQTQLIEFNPNLGDVTRATRVAYVKFMRKKMA 931
            |||:....|                ..:.||..|.:..:|.:|:......:.|..:.
  Rat   158 SDPVKDPSS----------------PGSSGLNQNSSDKLESDPSPWLTNPSIRRTFF-------- 198

  Fly   932 ADEVSLADDEGAPNGEGEKKPLDA-SGSKKSITSGGTGGGASMLAAAALRASVKNVDEKSGADGK 995
                        |:.:...|.:.| .|..|.:..|..|..|.|:.:||.:|...:|...:.:.|:
  Rat   199 ------------PDPQTSTKEISALKGMLKQLQPGPLGRAARMVLSAAHKAPPASVVSPNNSHGE 251

  Fly   996 PGTMGKPTDDKKAGDDKDKQQPPKDSKPSAGGPKPGDQKPTP---GAGAPKPQAAGTISKPGESQ 1057
            |.:......:.:|      ::|.:.:..|.|..:...::..|   .:..|..:|.|.
  Rat   252 PDSSHPERAEPRA------EEPNRKNNASRGKRRKVQEQRRPLSSSSSQPNRRATGR-------- 302

  Fly  1058 KKDAPAPPTKPGDTKPAAPKPGE-----------------SAKPEAAAKKEESSKTEASKPAATN 1105
                    ||....:|.|...|.                 .|.|..||...|||..:.:.|.:.:
  Rat   303 --------TKQRQQRPQAKSDGSGVQATGQCPICTGSFSIEALPRHAATCGESSPPQPASPTSLS 359

  Fly  1106 GAAKSAAPSAPSDAKPDS 1123
            .:......|:|..:.|.|
  Rat   360 SSESVLWVSSPESSPPPS 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trp	NP_476768.1	trp	16..776	CDD:273311
		ANK	64..>168	CDD:238125
		ANK repeat	69..98	CDD:293786
		ANK repeat	99..135	CDD:293786
		ANK repeat	137..168	CDD:293786
		TRP_2	178..236	CDD:285535
		BASP1	938..1158	CDD:283191	40/207 (19%)
Xndc1	NP_001316819.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000660
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910