DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip99C and Slc39a13

DIOPT Version :9

Sequence 1:	NP_001189313.1	Gene:	Zip99C / 43533	FlyBaseID:	FBgn0039714	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001277694.1	Gene:	Slc39a13 / 68427	MGIID:	1915677	Length:	374	Species:	Mus musculus

Alignment Length:	345	Identity:	155/345 - (44%)
Similarity:	200/345 - (57%)	Gaps:	64/345 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 WVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLLPEA 100
            |:.|||||:::||||:|||::||.|....   .:..|.:..||.|||||:|||||:|||||||||
Mouse    68 WICSLLGSLMVGLSGVFPLLVIPLEMGTL---LQSEAGAWRLRQLLSFALGGLLGNVFLHLLPEA 129

  Fly   101 WE---------------------GDNQDPSSHPSLRSGLWVLSGILIFTIVEKIFSGYASADEEN 144
            |.                     |:.|.......|  ||||::|.|.|..:||:|..    .:|:
Mouse   130 WAYTCNITPATGLAWPVSAPPAGGEGQSLQRQQQL--GLWVIAGFLTFLALEKMFLN----SKED 188

  Fly   145 PQPKCVEIANCLLRRHGGQLPEGETSESC--GGACDIEDVGKVCFLREQEQKSKERKEQPKKVAG 207
            |                .|.|..:.:.:.  ||.|..:...      |...::..|.   .||:|
Mouse   189 P----------------SQAPSKDPTAAALNGGHCLAQPAA------EPGLRAVVRN---LKVSG 228

  Fly   208 YLNLLANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQ 272
            |||||||:|||||||||||.|||||.:.|:|.|.|||||||||||||||||||:||.||.||:.|
Mouse   229 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQ 293

  Fly   273 LLTAGAGLLGALVAI---GGSGVTSAMEARTSWIMPFTAGGFLHIALVTVLPDLLKEEERKESIK 334
            ..||..|||||..||   ...||    |....||:|||:||||:||||.||||||:|::...|::
Mouse   294 FSTALGGLLGACFAICTQSPKGV----EETVVWILPFTSGGFLYIALVNVLPDLLEEDDPWHSLQ 354

  Fly   335 QLLALVFGIALMAVMTMLFE 354
            |:|.|..|:.:|.::::..|
Mouse   355 QVLLLCSGVLVMVLLSLFVE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip99C	NP_001189313.1	Zip	34..350	CDD:280666	154/339 (45%)
Slc39a13	NP_001277694.1	Zip	65..369	CDD:396884	154/338 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H62681
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3222
Isobase	1	0.950	-	0	Normalized mean entropy	S2015
OMA	1	1.010	-	-		QHG46433
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	1	1.000	-	-		FOG0001345
OrthoInspector	1	1.000	-	-		oto94980
orthoMCL	1	0.900	-	-		OOG6_108341
Panther	1	1.100	-	-	LDO	PTHR16950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1954
SonicParanoid	1	1.000	-	-		X5547
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750