DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip99C and slc39a6

DIOPT Version :9

Sequence 1:	NP_001189313.1	Gene:	Zip99C / 43533	FlyBaseID:	FBgn0039714	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001001591.1	Gene:	slc39a6 / 324303	ZFINID:	ZDB-GENE-030131-3023	Length:	742	Species:	Danio rerio

Alignment Length:	404	Identity:	98/404 - (24%)
Similarity:	167/404 - (41%)	Gaps:	102/404 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 YTPWVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLL 97
            |..|:...|...:|.|..:..:::||...::        ..:.||..|::.|||.|.||..|||:
Zfish   350 YIAWLGGFLSITLISLLALVGVVLIPLMNRV--------CFNFLLSFLVALAVGTLSGDALLHLI 406

  Fly    98 PEAWEG------DNQDPSSHPSLR---SGLWVLSGILIFTIVEKIFS-GYASADEENPQPKCVEI 152
            |.: :|      ..:......|||   :||..|||:.|..::|...: |....|:.....|.|::
Zfish   407 PHS-QGHHHHGHSEEHAEEEDSLRPVWTGLTALSGVYIMFLIEHFLTLGKMYKDKNQKVQKRVDL 470

  Fly   153 ANCLLRRHGGQLP-------EGETSESCGGAC---------------DIEDVGKVCFL------- 188
            ...:|...  :||       :.|.:|:.||..               ||:...| |..
Zfish   471 TTEVLESE--KLPSLEENDVKIEAAETNGGRALAEEEEVMLGAELYNDIDCENK-CHSHFHDTVG 532

  Fly   189 -------------------------------REQEQKSKERKEQPKKVAG-----YLNLLANSID 217
                                           |.....|::..||    ||     ::.::.:.:.
Zfish   533 QSDEQHHHHHDYHHILHHHHSQNHHPHTHTHRHTHSYSQQHFEQ----AGVATLAWMVIMGDGLH 593

  Fly   218 NFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLG 282
            ||:.|||:..:|......|:..:.|:..||:|||:||||:||::|.|...|....||:|..|.||
Zfish   594 NFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMSVRQAMLYNLLSALMGYLG 658

  Fly   283 ALVAIGGSGVTSAMEARTSWIMPFTAGGFLHIALVTVLPDLLKEEERKES-------IKQLLALV 340
            .::   |..:....|...:||...|||.|:::|||.::|::|..:..:..       :.|...::
Zfish   659 MII---GILIGHYAENVATWIFALTAGLFMYVALVDMVPEMLHNDASEAGFSHYGFFLLQNAGIL 720

  Fly   341 FGIALMAVMTMLFE 354
            .|..:|.::. :||
Zfish   721 LGFGIMLIIA-VFE 733

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip99C	NP_001189313.1	Zip	34..350	CDD:280666	95/397 (24%)
slc39a6	NP_001001591.1	Zip	351..730	CDD:280666	95/397 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820