Protein Alignment Zip99C and SLC39A5

DIOPT Version :10

• Sequence 1: NP_733319.1
• Gene: Zip99C / 43533
• FlyBaseID: FBgn0039714
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_775867.2
• Gene: SLC39A5 / 283375
• HGNCID: 20502
• Length: 540
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 99/305 - (32%)
• Similarity: 139/305 - (45%)
• Gaps: 38/305 - (12%)

  Fly    75 KLLRVLLSF----AVGGLLGDVFLHLLPEAWEGDNQDPSSHP--SLRSGLWVLSGILIFTIVEKI 133
            :|||.||.|    |||.|.||..|||||.|.||.:..|...|  .|..||.||.|:.:..::|.:
Human   240 RLLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304

  Fly   134 FSGYASADEENPQPKCVEIANCLLRRHGGQLPEGETSESCGGACDIEDVGKVCFLREQEQKSKER 198
            .   ........:|:|     |  ||....|.........|....::.:........|.|:.|..
Human   305 L---GLLRHRGLRPRC-----C--RRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNS 359

  Fly   199 KEQPKKV----------------AGYLNLLANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHE 247
            :..|...                ..::.||.:.:.|.|.|||:..:|...|..|:..|.|:..||
Human   360 QHPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHE 424

  Fly   248 IPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLGALVAIGGSGVTSAMEARTSWIMPFTAGGFL 312
            :|||:||||:||:||.|   ..|..||:..:|.||...|:.|.|::......|.|:...|||.||
Human   425 LPHELGDFAMLLQSGLS---FRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFL 486

  Fly   313 HIALVTVLPDLLKEEE---RKESIKQLLALVFGIALMAVMTMLFE 354
            ::|||.:||.||:..|   ....:.|.|.|:.|..||..:|:|.|
Human   487 YVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip99C	NP_733319.1	Zip	34..350	CDD:396884	96/299 (32%)
SLC39A5	NP_775867.2	Zip	248..504	CDD:396884	85/268 (32%)