DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip99C and Slc39a12

DIOPT Version :9

Sequence 1:	NP_001189313.1	Gene:	Zip99C / 43533	FlyBaseID:	FBgn0039714	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001012305.1	Gene:	Slc39a12 / 277468	MGIID:	2139274	Length:	689	Species:	Mus musculus

Alignment Length:	341	Identity:	100/341 - (29%)
Similarity:	153/341 - (44%)	Gaps:	70/341 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLLPEAWEG 103
            |:||:.::    :|         ...:|.|     |.:|::.:..|||.|.||..|||:|:....
Mouse   381 SMLGTALV----LF---------HSCEENY-----SLILQLFVGLAVGTLSGDALLHLIPQVLGL 427

  Fly   104 DNQDPS---SHPSLRSGLW----VLSGILIFTIVEKIFSGYASADEENPQPKCVEIANCLL--RR 159
            ..|:..   .|.| :|.:|    :|.||..|.::||.|....|     |..|.:.:.|..:  ..
Mouse   428 HKQEAEFGHFHES-QSPIWKLLGLLGGIHGFFLIEKCFILLVS-----PNTKGLPLVNEHVGHTH 486

  Fly   160 HGGQLPEGETSESCGGACDI------ED-------VGKVCFLREQEQKSKERKEQPKKVAGYLNL 211
            |.|..||.....|.|.:...      ||       :|.|        .:..|..:...:...:.|
Mouse   487 HLGLNPELNDQSSGGKSISTIQLKGPEDSQTTVLPIGNV--------PASNRNGKTISLLAIMIL 543

  Fly   212 LANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQLLTA 276
            :.:|:.||..||.:..:|..|...|:..|.|||.||||||:||||:||.||.|    .|..:|
Mouse   544 VGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLS----VRTAIL-- 602

  Fly   277 GAGLLGALVAIGG--SGVTSAMEART-SWIMPFTAGGFLHIALVTVLPDLLKEEERKESIKQLLA 338
             ...|.||.|..|  .|::.:.:.|. .||:..|||.||:::||.:||::...:.::..:..||.
Mouse   603 -MNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMLPEMTHVQTQRPWMTFLLQ 666

  Fly   339 LV------FGIALMAV 348
            .|      |.:.|:||
Mouse   667 NVGLVLGWFSLLLLAV 682

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip99C	NP_001189313.1	Zip	34..350	CDD:280666	100/341 (29%)
Slc39a12	NP_001012305.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..303
		Zip	369..681	CDD:280666	98/338 (29%)
		XEXPHE-motif. /evidence=ECO:0000250	578..583		4/4 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820