Protein Alignment Zip99C and SLC39A6

DIOPT Version :9

• Sequence 1: NP_001189313.1
• Gene: Zip99C / 43533
• FlyBaseID: FBgn0039714
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_036451.4
• Gene: SLC39A6 / 25800
• HGNCID: 18607
• Length: 755
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 96/462 - (20%)
• Similarity: 172/462 - (37%)
• Gaps: 128/462 - (27%)

  Fly     9 DEHIAMIYSNLMDQYMPEYFKSFEYTPWVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPAD 73
            |....:|:::.....:|....|.:.. ||...:...:|....:..:|::|.   |.:..:|
Human   299 DARSCLIHTSEKKAEIPPKTYSLQIA-WVGGFIAISIISFLSLLGVILVPL---MNRVFFK---- 355

  Fly    74 SKLLRVLLSFAVGGLLGDVFLHLLPEAWEG-----DNQDPS---------SHPSLRS-------- 116
             .||..|::.|||.|.||.||||||.:...     .:::|:         ||.|.::
Human   356 -FLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFD 419

  Fly   117 ----GLWVLSGILIFTIVEKIFS------------------------------------------ 135
                ||..|.|:....:||.:.:
Human   420 STWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKV 484

  Fly   136 -------GYASADEENP------QPKCVEIANCLL-RRHGGQLPEGETSESCGGACDI---EDVG 183
                   ||..||.:.|      ||..:|....:: ..|..::........|...|..   :.:|
Human   485 DTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLG 549

  Fly   184 KVCFL-----------------------REQEQKSKERKEQPKKVAGYLNLLANSIDNFTHGLAV 225
            :...|                       ..|....:|.|:.......::.::.:.:.||:.|||:
Human   550 QSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAI 614

  Fly   226 AGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLGALVAIGGS 290
            ..:|......|:..:.|:..||:|||:||||:||::|.:   ..:|.|..|.:.:|..|....|.
Human   615 GAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMT---VKQAVLYNALSAMLAYLGMATGI 676

  Fly   291 GVTSAMEARTSWIMPFTAGGFLHIALVTVLPDLLKEEERKESIK-------QLLALVFGIALMAV 348
            .:....|..:.||...|||.|:::|||.::|::|..:.......       |...::.|..:|.:
Human   677 FIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLL 741

  Fly   349 MTMLFEH 355
            :: :|||
Human   742 IS-IFEH 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip99C	NP_001189313.1	Zip	34..350	CDD:280666	89/430 (21%)
SLC39A6	NP_036451.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..186
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..246
		Zip	323..742	CDD:308248	89/430 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820