DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS8 and rps8a

DIOPT Version :9

Sequence 1:	NP_001247362.1	Gene:	RpS8 / 43532	FlyBaseID:	FBgn0039713	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_999958.1	Gene:	rps8a / 407690	ZFINID:	ZDB-GENE-030131-8626	Length:	208	Species:	Danio rerio

Alignment Length:	208	Identity:	143/208 - (68%)
Similarity:	172/208 - (82%)	Gaps:	2/208 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGISRDSAHKRRATGGKRKSLRKKRKFELGRPAANTKLGSGRVHKVRTRGGNTKLRALRLETGNF 65
            ||||||:.||||.||||||.:.||||:||||||||||:|..|:|.:|.||||.|.|||||:.|||
Zfish     1 MGISRDNWHKRRRTGGKRKPVHKKRKYELGRPAANTKIGPRRIHTIRVRGGNKKYRALRLDVGNF 65

  Fly    66 AWASEGVARKTRIADVVYNASNNELVRTKTLVKNSIVVIDATPFRQWYEAHYVLPLGRKRNPKHA 130
            :|.||...|||||.||||||||||||||||||||.:|::|:||:|||||:||.||||||:..|..
Zfish    66 SWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCVVLVDSTPYRQWYESHYALPLGRKKGAKLT 130

  Fly   131 QKEDENDVLTKKRSEKVMKKYLERQKYGKVEQALEDQFTSGRILACISSRPGQCGRSDGYILEGK 195
            .:|:|  :|.||||:||.||:..|:|..|:...||:||..|::|||||||||||||:|||:||||
Zfish   131 PEEEE--ILNKKRSKKVQKKFTLRRKTAKISPLLEEQFLQGKLLACISSRPGQCGRADGYVLEGK 193

  Fly   196 ELEFYLKKIKSKK 208
            ||||||:|||:||
Zfish   194 ELEFYLRKIKAKK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS8	NP_001247362.1	PTZ00148	1..208	CDD:240292	141/206 (68%)
rps8a	NP_999958.1	PTZ00148	1..206	CDD:240292	141/206 (68%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		19/25 (76%)
		Ribosomal_S8e_like	5..190	CDD:211392	124/186 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595828
Domainoid	1	1.000	272	1.000	Domainoid score	I1760
eggNOG	1	0.900	-	-		E1_COG2007
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2660
OMA	1	1.010	-	-		QHG53636
OrthoDB	1	1.010	-	-		D1278610at2759
OrthoFinder	1	1.000	-	-		FOG0001886
OrthoInspector	1	1.000	-	-		otm26354
orthoMCL	1	0.900	-	-		OOG6_100802
Panther	1	1.100	-	-	O	PTHR10394
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1250
SonicParanoid	1	1.000	-	-		X1244
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800