DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS8 and NSA2

DIOPT Version :9

Sequence 1:	NP_001247362.1	Gene:	RpS8 / 43532	FlyBaseID:	FBgn0039713	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_055701.1	Gene:	NSA2 / 10412	HGNCID:	30728	Length:	260	Species:	Homo sapiens

Alignment Length:	120	Identity:	25/120 - (20%)
Similarity:	46/120 - (38%)	Gaps:	27/120 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 PFRQWYEAH-----YVLPLGRKRNPKHAQKEDENDVLTKK-------------RSEKV-MKKYLE 153
            |..::.|.|     |.|....|:..|.:::..|.....||             .:||: |||.::
Human     2 PQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTIK 66

  Fly   154 RQKYGKVEQALEDQFTSGRILACISSRPGQCGRSDGYILEGKELEFYLKKIKSKK 208
            ..:....:|..:::...|.:.|.:..|.||.        ..|.|...:|:.:.:|
Human    67 MHEKRNTKQKNDEKTPQGAVPAYLLDREGQS--------RAKVLSNMIKQKRKEK 113

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS8	NP_001247362.1	PTZ00148	1..208	CDD:240292	24/118 (20%)
NSA2	NP_055701.1	NSA2	4..260	CDD:211393	24/118 (20%)
		Nuclear localization signal. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00768	11..18		1/6 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..41		3/20 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2007
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900