DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15514 and Zbed4

DIOPT Version :9

Sequence 1:	NP_651739.1	Gene:	CG15514 / 43531	FlyBaseID:	FBgn0039712	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_852077.1	Gene:	Zbed4 / 223773	MGIID:	2682302	Length:	1168	Species:	Mus musculus

Alignment Length:	236	Identity:	62/236 - (26%)
Similarity:	93/236 - (39%)	Gaps:	59/236 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CKHCEKTLSSKHT----SSNLTRHLIRNHKLLARSIFAGEEGKMLAELKDELEASASEDLSMELG 82
            |::|...:|....    :|.|.|||.|.|.            :::...||.|.||.:......|.
Mouse   477 CRYCSCVISRGKKGDVGTSCLMRHLYRRHP------------EVVGNQKDFLGASLANSPYATLA 529

  Fly    83 EGETKSAVRGI--MNAKLEQEQMERHSQEEMRNKVIGKNNKLWAHFIRISEFMAK--CMHCGKTL 143
            ..|:.|.:..:  :..|..|.....:|:         |.:|||.||...|....|  |:|||:|:
Mouse   530 SAESSSKLTDLPAVVRKNHQGVFPTNSK---------KTSKLWNHFSICSADSTKVVCLHCGRTI 585

  Fly   144 SSKHSSSNLMRHIVRRHTSLAKTLNHSHQHLMTPKKD-SYASLERRQA---------------AD 192
            |.....:||....:.||      |...|.|::  |.| |.|:|.|...               .|
Mouse   586 SRGKKPTNLGTSCLLRH------LQRFHGHVL--KNDVSEATLSRSPGIRRPLGIELSGPSSFRD 642

  Fly   193 PLEKVNFDDVDSIIEKVADHLEEEVTSISLQEPFYEYVVDN 233
            ..||  |.|...:.:|:.. |..|:.::.|| |:  .:|||
Mouse   643 STEK--FYDSHPVAKKITS-LIAEMIALDLQ-PY--SLVDN 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15514	NP_651739.1	zf-BED	6..47	CDD:280965	9/28 (32%)
CG15514	NP_651739.1	zf-BED	120..160	CDD:280965	15/41 (37%)
Zbed4	NP_852077.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..55
		zf-BED	118..165	CDD:335142
		zf-BED	289..335	CDD:335142
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	362..443
		zf-BED	460..506	CDD:335142	9/28 (32%)
		zf-BED	561..607	CDD:335142	18/51 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1040..1059
		Required for homodimerization and nuclear accumulation. /evidence=ECO:0000250\|UniProtKB:O75132	1083..1168
		Dimer_Tnp_hAT	1085..>1134	CDD:368565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910