Protein Alignment Cad99C and Pcdhb20

DIOPT Version :10

• Sequence 1: NP_733314.1
• Gene: Cad99C / 43528
• FlyBaseID: FBgn0039709
• Length: 1706
• Species: Drosophila melanogaster
• Sequence 2: NP_444375.2
• Gene: Pcdhb20 / 93891
• MGIID: 2136758
• Length: 799
• Species: Mus musculus
• Alignment Length: 708
• Identity: 189/708 - (26%)
• Similarity: 297/708 - (41%)
• Gaps: 147/708 - (20%)

  Fly   387 ISSSQAEGY---VDENSPIGTRVL----DAHGNPISFMTTDADLSDSDPKPDYIYELTTPSFNVT 444
            :|.:.||..   |.|.:.||:.|.    |.........:.:|.:...|.|...:..|      :|
Mouse    23 LSQASAESLRYSVAEETEIGSFVANLAKDLGLGVAELSSREARVVSDDNKKHLLLNL------LT 81

  Fly   445 GDGILVVNEENLDRD----PPAPGRFKFQVVAREP----RTNAASAPLSLTVHLRDVNDNAPKLA 501
            ||.:|   .|.|||:    ...|....||||...|    |..         :|:||:||::|..
Mouse    82 GDMLL---NERLDREELCGSTQPCVLPFQVVLENPLQFYRAE---------LHVRDINDHSPTF- 133

  Fly   502 MVAPISITAGDQSESRLVTQVTAT-------DNDEGPNAVVTYSI---------YHVSNNG---- 546
            :...|:|..   |||   |.:.||       |.|.|.|::..|||         .|.|.:|
Mouse   134 LDKEITIKI---SES---TTIGATFLIENAQDLDIGSNSLQDYSISPSSYFYVKIHDSGDGKIYP 192

  Fly   547 ---IQKFTINATTGEIRTQGRLLAGEQYSITVQATDIGG--LSSQAIVEVSVTPGPNTKPPRFQK 606
               :.|...:....|:|            :|:.|.|.|.  .|...::.:.|. ..|...|.|.:
Mouse   193 ELVLDKALDHEEESELR------------LTLTALDGGSPPRSGTTLIVIKVL-DINDNAPEFAQ 244

  Fly   607 PIYEVQVSEGAEINSTVTVVHAEDPENDAVVYSIIS------GNDLRQ-FAVGQESGVIIVIRKL 664
            ..|||||.|...|.|::|.:.|:|  .|..:|..||      ..|:|: |.:...||.:.:...:
Mouse   245 SFYEVQVPEDMPIGSSITAISAKD--LDMGIYGKISYSFLHASEDIRKTFEINPTSGEVNLRSLM 307

  Fly   665 DRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEASTLPYVFQVEEGKAQASVGVVHA 729
            |.|.:..|.:.::|.|.||||:..|:::||.||||..||...|::...  :.|..::..|.:...
Mouse   308 DFEVIQSYSVNIQATDGGGLSAKCTLSVKVLDINDNAPEVIMSSVTKA--IPENASETLVALFSV 370

  Fly   730 TDADEGINAEITYSIPTDIPFTINATSGE---ILTAKELDYEQLNEYKFVVTAKD-GAPDARLGT 790
            .|.|.|.|..|..||..|:||.:..:...   :|:.|.||.|:..||...:||.| |.|  ||.|
Mouse   371 RDQDSGDNGRILCSIQDDLPFILKPSFKNFFTLLSEKALDRERRAEYNITITASDMGTP--RLTT 433

  Fly   791 A-SVTVMVLDLPDEVPKFSDARIDVHIPENEENFL-VATVQAFDPD--SMPEITYVLRKGN---- 847
            . ::.|.|.|:.|..|.|:.....:.|.||....| :.|:.|.|.|  |...|||.|....
Mouse   434 QHTIRVQVSDINDNAPAFTQTSYTMFIYENNSPALHIGTISATDKDSGSNAHITYSLLPAQDPEL 498

  Fly   848 --AELFKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGP---GDTILLVVDVEDRNDLP-- 905
              |.|..::..:|::..::.||||..:..:..:|.  .|...|   ..|::.||.::|.::.|
Mouse   499 ALASLISINADNGQLFALRALDYEVLQAFEFQVGA--TDRGSPALSSQTLVRVVVLDDNDNAPFV 561

  Fly   906 ---------------PRFITVPDPVTVNDDQGIGTIIATLPAIDGDGTSPGNV-VRYEIVGRGKA 954
                           ||   |.:|         |.::..:.|:|.|  |..|. :.:::: :...
Mouse   562 LYPMQNASAPCTELLPR---VAEP---------GYLVTKVVAVDRD--SGQNAWLSFQLL-KATE 611

  Fly   955 PKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGEPQLSSVAPLRVDVHHLLSSG 1012
            |..|.|....|.||....|.:.:..::::.:...|.|:|..|:    .|.:|.|:..|
Mouse   612 PGLFSVWAHNGEVRTTRLLSERDVPKHRLVLLVKDNGDPPRSA----SVTLHVLVVDG 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad99C	NP_733314.1	CA_like	68..140	CDD:481204
		Cadherin_repeat	146..259	CDD:206637
		Cadherin_repeat	280..383	CDD:206637
		Cadherin_repeat	393..496	CDD:206637	30/117 (26%)
		Cadherin_repeat	518..594	CDD:206637	21/100 (21%)
		Cadherin_repeat	608..699	CDD:206637	34/97 (35%)
		Cadherin_repeat	710..802	CDD:206637	30/96 (31%)
		Cadherin_repeat	814..903	CDD:206637	27/100 (27%)
		Cadherin_repeat	915..1005	CDD:206637	18/90 (20%)
		Cadherin_repeat	1041..1144	CDD:206637
		Cadherin_repeat	1159..1264	CDD:206637
Pcdhb20	NP_444375.2	Cadherin_2	30..112	CDD:462413	23/90 (26%)
		Cadherin_repeat	137..238	CDD:206637	28/119 (24%)
		Cadherin_repeat	247..343	CDD:206637	35/97 (36%)
		Cadherin_repeat	356..447	CDD:206637	30/92 (33%)
		Cadherin_repeat	455..557	CDD:206637	27/103 (26%)
		Cadherin_repeat	580..664	CDD:206637	21/99 (21%)
		Cadherin_C_2	687..769	CDD:465139