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Protein Alignment Cad99C and Pcdhb2

DIOPT Version :10

Sequence 1:	NP_733314.1	Gene:	Cad99C / 43528	FlyBaseID:	FBgn0039709	Length:	1706	Species:	Drosophila melanogaster
Sequence 2:	NP_001102593.2	Gene:	Pcdhb2 / 498843	RGDID:	1563132	Length:	793	Species:	Rattus norvegicus

Alignment Length:	762	Identity:	206/762 - (27%)
Similarity:	305/762 - (40%)	Gaps:	172/762 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   411 GNPISFMTTDADLSD-SDPKPDY--------IYELTTPSFNVTGDGILVVNEENLD--------- 457
            |||:.....:..:.| :|..|.:        |.|:|.|     |...|:...::||
  Rat   107 GNPLEIFQAELQIRDINDHSPVFLDKKIILKISEITAP-----GTTFLIERAQDLDVGSNSLQTY 166

  Fly   458 ------------RDPP----APGRFKFQVVAREPRT---------NAASAPLSLTVHL----RDV 493
                        :|.|    .|.....:|:.||.|:         :..:.|.|.|||:    .|:
  Rat   167 SISPNFHFHLNLQDSPDGTVLPQLVLDKVLDREERSEIRLILTALDGGNPPRSGTVHILIEVLDI 231

  Fly   494 NDNAPKLAMV-----APISITAGDQSESRLVTQVTATDNDEGPNAVVTYSIYHVSNNGIQKFTIN 553
            |||||..:.:     .|.:...|.|     |..|:|.|.|.|.|..:||:....|.:..:.|.:|
  Rat   232 NDNAPAFSKLRYEVQVPENSPVGSQ-----VATVSAKDLDIGDNGQITYAFSQASEDIRKTFRMN 291

  Fly   554 ATTGEIRTQGRLLAG-------EQYSITVQATDIGGLSSQAIVEVSVTPGPNTKPPRFQKPIYEV 611
            ||:|||     ||..       :.|::.|||||.||||..::|.|.| ...|..||......:..
  Rat   292 ATSGEI-----LLVKTLDFESIQAYTVYVQATDGGGLSGSSVVFVQV-KDLNDNPPELTMSTFTN 350

  Fly   612 QVSEGAEINSTVTVVHAEDP---ENDAVVYSIISGNDLRQFAVG---QESGVIIVIRKLDRESLT 670
            .:.|.|. .:.:.|....||   :|..:|.||  ..|| .|.:.   :....::....||||:.|
  Rat   351 HIPENAP-ETVIAVFSVADPDSGDNGKMVCSI--QEDL-PFVLKPSVENLYTLMTNTALDRETRT 411

  Fly   671 RYQLILKAEDTG--GLSSSATVNIKVTDINDKNPEFEASTLPYVFQVEEGKAQA-SVGVVHATDA 732
            :|.:.:...|.|  .|::..|:.:.|:||||..|.|..::  |...|.|..:.| .:|.:.|||:
  Rat   412 QYNITITVSDMGTPRLTTQHTIAVYVSDINDNAPAFTQTS--YTIFVRENNSPALHIGTISATDS 474

  Fly   733 DEGINAEITYS-IPTDIP-------FTINATSGEILTAKELDYEQLNEYKFVVTAKDGAPDARLG 789
            |.|.||.|||| :|...|       .:|||.:|::...:.||||.|..::|.|:|.||...|...
  Rat   475 DSGSNAHITYSLLPPQDPQLALNSLISINADNGQLFALRALDYEALQAFEFHVSAVDGGLPALSS 539

  Fly   790 TASVTVMVLDLPDEVP------KFSDARIDVHIPE-NEENFLVATVQAFDPDSMPE--ITYVLRK 845
            .|.|.::|||..|..|      :.:.|.....:|. .|..:||..|.|.|.||...  :::.|.|
  Rat   540 QAPVRLVVLDDNDNAPFVLYPLQNASAPCTELLPRAAEPGYLVTKVVAVDRDSGQNAWLSFQLLK 604

  Fly   846 GNAE-LFKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGPGDTILLVVDVEDRNDLPPRFI 909
            .... ||.|...:|||||.:.|......:|:|               :|||.|    |..|||..
  Rat   605 ATEPGLFSVWAHNGEVRTTRLLGERDVLKHRL---------------LLLVKD----NGDPPRSA 650

  Fly   910 TVPDPVTVNDDQGIGTIIATLPAIDGDGTSPGNVVR-YEIVGRGKAPKYFQVD--PDTGAVRI-- 969
            :|...|.:.|  |.......||.:..|.....|.:. |.::........|.:.  ...| ||:
  Rat   651 SVTLHVLLVD--GFSQPYLPLPEVARDAAQDENALTLYLVIALASVSSLFLLSLLLFVG-VRLCR 712

  Fly   970 RDELRKEEDTEYQVDIRAYDLGEPQLSSVAPLRVDVH---HLLSSGNNEIKLDNKLESGTGMSSE 1031
            ||              ||..||...:.       :.|   ||:..|.          :||...|.
  Rat   713 RD--------------RATSLGGCSMP-------EGHFPGHLVDVGG----------AGTLSQSY 746

  Fly  1032 SIGLAFSDDSYTTSVPESMEANSTLKLIQIVNSKTSGDGPPAFRCEF 1078
            ...:..|.|   |..|:.......:....:.||:...|..|::|..|
  Rat   747 QYEVCLSGD---TRTPDFKFLKPIIPNFLLQNSERENDTNPSYRNSF 790

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.