Protein Alignment Cad99C and Pcdh9

DIOPT Version :10

• Sequence 1: NP_733314.1
• Gene: Cad99C / 43528
• FlyBaseID: FBgn0039709
• Length: 1706
• Species: Drosophila melanogaster
• Sequence 2: NP_001074846.1
• Gene: Pcdh9 / 211712
• MGIID: 1306801
• Length: 1237
• Species: Mus musculus
• Alignment Length: 1177
• Identity: 289/1177 - (24%)
• Similarity: 452/1177 - (38%)
• Gaps: 272/1177 - (23%)

  Fly    60 PPELPIFGDP--------------DTEIALNLVFPKGQ-PIFQLN---GKKLQLLQPLDRD---- 102
            |..:||...|              ...:...||...|. |:.:::   |:.......:||:
Mouse    35 PENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCA 99

  Fly   103 -----EENLSHIVFQVSCTTRSTGKKRTIPIIVRVSDINDNAPRFMNTPYEVTVPESTPVGTTIF 162
                 |||  ...|::..........|.|.|.:.|.|.|||||.|.:....:::||:|.:.:. |
Mouse   100 GASYAEEN--ECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSR-F 161

  Fly   163 RNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSADGYGTFAISFPHQG----QVTVAKTLDFEK 223
            ....|.|.|.|.||:..|.:..|.           ..:|...:..| :|    |:.|.:.||.|:
Mouse   162 PIPSATDPDTGFNGVQHYELLNGQ-----------SVFGLDIVETP-EGEKWPQLIVQQNLDREQ 214

  Fly   224 IQTYYLTIVASDRARNTADRLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACINPEYSASVPAG 288
            ..||.:.|...|   ....:.|||..|.|.::|.||..|.|       .:|     :....:|..
Mouse   215 KDTYVMKIKVED---GGTPQKSSTAILQVTVSDVNDNRPVF-------KEG-----QVEVHIPEN 264

  Fly   289 SLLGVLTVLPERIQAVDLDT-INSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKY 352
            :.:|...:   ::.|.|.|. .|:.|||.|.:.:.......|.::.:||::...:::|......:
Mouse   265 APVGTSVI---QLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIH 326

  Fly   353 DIIVKAEEVSPGPQRFTTAKLEIFVKPVDANPP------VISSSQAEGYVDENSPIGTRV----- 406
            .:.|.|.:.|..|.|   |.:.|.|..|:.|||      :||......|:.|..|:.|::
Mouse   327 KVTVLASDGSSTPAR---ATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITV 388

  Fly   407 ----LDAHGNPISFMTTDADLSDSDPKPDYIYELTTPSFNVTGDGILVVNEENLDRDPPAPGRFK 467
                .|.:|..|.|:..:.        |.::..:....:.:....:|         |......|.
Mouse   389 SDKDTDVNGKVICFIEREV--------PFHLKAVYDNQYLLETSSLL---------DYEGTKEFS 436

  Fly   468 FQVVAREPRTNAASAPLSLTVHLRDVNDNAPKLAM-VAPISITAGDQSESRLVTQVTATDNDEGP 531
            |::||.:....:.:....:.|.|.|.|||.|.... |..:|::..:: ....:|.::|||.|.|.
Mouse   437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNR-RGLYLTTISATDEDSGK 500

  Fly   532 NAVVTYSIYHVSNNGIQKFTINATTGEIRTQGRLL---AGEQYSITVQATDIG--GLSSQAIVEV 591
            ||.:.|.:    ......|.::..|| :.|..|:.   ..|::..||.|.|.|  .|.|||.|.|
Mouse   501 NADIVYQL----GPNASFFDLDRKTG-VLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIV 560

  Fly   592 SVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDP---ENDAVVYSIISGNDLRQFAVGQ 653
            :|. ..|...|:|....::..|||.....|||.|:...|.   ||.||..||:  ||...|.:..
Mouse   561 TVL-DENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSIL--NDNENFVLDP 622

  Fly   654 ESGVIIVIRKLDRESLTRYQLILKAEDTG--GLSSSATVNIKVTDINDKNPEFEASTLPYVFQVE 716
            .||||......|||..:.|...:||.|.|  ..||:|.|.|.|.|:||.:|...:......|::.
Mouse   623 YSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLV 687

  Fly   717 EGKA--QASVGVVHATDADEGINAEITYSIPTDIP---FTINATSGEILTAKELDYEQLNEYKFV 776
            ...|  .:.|..|.|.|.|.|:|||:.|:|.:...   |.|:..:|.|...::.....:..::.|
Mouse   688 PLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLV 752

  Fly   777 VTAKD-GAPDAR----------LGTASVTVMVLDLPDEVPKFSDARIDVHI-----PENEENFL- 824
            |...| |.|.|.          ..||..|..:.||   :.:..:..:|.:|     |...|::|
Mouse   753 VNISDLGYPKALHTLVLVFLYVNDTAGNTSYIYDL---IRRTMETPLDRNIGDSGQPYQNEDYLT 814

  Fly   825 ----------VATVQAFDPDSMPEITYVLRKGNAELFKVSEKSGEVRTIKGLDYESQKQHQLTIG 879
                      |..|..|       :|.::|..:|..||.:::|.:     |.::.|..|
Mouse   815 IMIAIVAGAMVVIVVIF-------VTVLVRCRHASRFKAAQRSKQ-----GAEWMSPNQ------ 861

  Fly   880 TIENDGN---------GPGDTILLVVDVEDR--NDLPPRFITVPDPVTVNDDQGIGTIIATLPA- 932
              ||..|         .|..::|..|.:|:.  :|      .|.:|:.       |||  :|||
Mouse   862 --ENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDD------AVHEPIN-------GTI--SLPAE 909

  Fly   933 IDGDGTSPGNVVRYEIVGR---GKAPKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGEPQ 994
            ::..|           :||   |.||      |.|......| |.|.           |....||
Mouse   910 LEEQG-----------IGRFDWGPAP------PTTFKPNSPD-LAKH-----------YKSASPQ 945

  Fly   995 ----LSSVAPLRVDVHHLLSSGNNEIKLDNKLESGTG-MSSESIGLAFSDDSYTTSVPESMEANS 1054
                |....|:.|..||::    .|:.|||....|.. :|..|   :.|.|.::.|...|.....
Mouse   946 PAFHLKPDTPVSVKKHHVI----QELPLDNTFVGGCDTLSKRS---STSSDHFSASECSSQGGFK 1003

  Fly  1055 TLKLIQI--VNSKTSGDGPPAF--RCEFVSGNGGGIFNLSSADHGCNLLLIQPLDFENKSSYS-L 1114
            |...:..  .||.:..|..|..  :|.     |...|::.                ||:.|:| .
Mouse  1004 TKGPLHTRQCNSYSKNDNIPVTHQKCP-----GSTSFHIR----------------ENEESHSES 1047

  Fly  1115 QLRLTSH 1121
            |.|:|.|
Mouse  1048 QRRVTFH 1054

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad99C	NP_733314.1	CA_like	68..140	CDD:481204	20/98 (20%)
		Cadherin_repeat	146..259	CDD:206637	30/116 (26%)
		Cadherin_repeat	280..383	CDD:206637	23/103 (22%)
		Cadherin_repeat	393..496	CDD:206637	19/111 (17%)
		Cadherin_repeat	518..594	CDD:206637	26/80 (33%)
		Cadherin_repeat	608..699	CDD:206637	36/95 (38%)
		Cadherin_repeat	710..802	CDD:206637	28/107 (26%)
		Cadherin_repeat	814..903	CDD:206637	23/115 (20%)
		Cadherin_repeat	915..1005	CDD:206637	23/97 (24%)
		Cadherin_repeat	1041..1144	CDD:206637	18/86 (21%)
		Cadherin_repeat	1159..1264	CDD:206637
Pcdh9	NP_001074846.1	Cadherin_repeat	29..138	CDD:206637	21/104 (20%)
		Cadherin_repeat	146..248	CDD:206637	31/117 (26%)
		Cadherin_repeat	258..354	CDD:206637	23/101 (23%)
		Cadherin_repeat	370..465	CDD:206637	19/111 (17%)
		Cadherin_repeat	473..568	CDD:206637	30/101 (30%)
		Cadherin_repeat	576..671	CDD:206637	37/96 (39%)
		Cadherin_repeat	687..776	CDD:206637	22/88 (25%)
		Protocadherin	777..1000	CDD:462451	68/296 (23%)