DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and matn1

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001025613.1	Gene:	matn1 / 595001	XenbaseID:	XB-GENE-957559	Length:	490	Species:	Xenopus tropicalis

Alignment Length:	354	Identity:	69/354 - (19%)
Similarity:	129/354 - (36%)	Gaps:	119/354 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 DFTCRSANYDRTSG----ACELSELDRLTLAGSQAFQVNDGSDYLENHCVDEPNKLCEFKRLPGR 302
            |.:.|:    |.||    |..:..:|:.||....:..:::..||:|::                .
Frog   160 DISARA----RESGLEIYAIGVGRVDKNTLRQIASEPLDEHVDYVESY----------------S 204

  Fly   303 ILKTVDSVYQEVSSI---------DECRELCLNSP--YRC---HSYDYNDTGDMVCRLSHHSRAT 353
            :::.:...:||...:         .:|.::|:::|  |.|   ..:..|:.| ..|.....|...
Frog   205 LIEKLSKKFQEAFCVTADLCSTGDHDCEQICVSTPGSYTCACRDGFTLNEDG-KTCNACGASAVD 268

  Fly   354 LADVQEPFLEV-PEASTYELTSCY-NVTIE-CGGGDMLARIRTSKLFNGKVYAKGSPK------- 408
            |..:.:....| ||  .:||...: |..:| ...||..|.:       |.|....|.:
Frog   269 LVFLIDGSKSVRPE--NFELVKQFINQIVESMDVGDHRAHV-------GLVQYSSSVRQEFPLGR 324

  Fly   409 -SCSVDVKSALDFELRMNYHD------------LECNVRQSTAGR-----------------YVN 443
             :...|:|||:.   :|:|.:            ::.:...|:.||                 |:|
Frog   325 YTSKKDIKSAVK---KMSYMEKGTMTGQALQYLIDNSFAISSGGRPAVPKVGIVFTDGRSQDYIN 386

  Fly   444 DIIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVIVESPNVIMRITSR 508
            |..::       :.:||      |.:....|.|.|:.::|     .::.|.:||.        |.
Frog   387 DAALR-------AKELG------YKMFAVGVGNAVEEELR-----MIASEPVVEH--------SF 425

  Fly   509 DGSDMMRSAEVGDPLALKFEIVDEQSPYE 537
            ..:|.....|:|..|.:|  |..|::|.|
Frog   426 YTADFKAMKEIGKKLQMK--ICVEENPCE 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532	12/46 (26%)
		PAN_1	294..373	CDD:278453	16/93 (17%)
		ZP	381..615	CDD:214579	39/195 (20%)
matn1	NP_001025613.1	vWA_Matrilin	35..258	CDD:238752	21/118 (18%)
matn1	NP_001025613.1	vWFA	265..489	CDD:381780	47/228 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000