DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and T01D1.8

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001300591.1	Gene:	T01D1.8 / 3896729	WormBaseID:	WBGene00044641	Length:	189	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	39/188 - (20%)
Similarity:	70/188 - (37%)	Gaps:	68/188 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 FQVNDGSDYLENHCVDEPNKLCEFKRLPGRILKTVDSVYQEVSSIDECRELCLNSPYRCHSYDYN 337
            :.|:.|||.|                  |||:.:..::..|:                .||::.|
Worm    53 YSVHHGSDKL------------------GRIVTSKVNIGDEI----------------YHSWNCN 83

  Fly   338 DTGD----MVCRLSHHSRATLADVQEPFLEVPEASTYELTSCY---NVTIECG-GGDMLARIRTS 394
            .:||    :.|.:.::  .|::|..|..:...:....:...|.   |:..:.. .||:.|.|
Worm    84 YSGDHKNYLFCVMVNN--CTISDSGEEEIGTRKIQIIDENGCSVFPNILPDISYQGDLSAGI--- 143

  Fly   395 KLFNGKVYAKGSPKSCSVDV-KSALDF--ELRMNYHDLE------CNVRQSTAGRYVN 443
                 ||:|      .::|| .:|:.|  .::|.:.|.|      |. .|....||:|
Worm   144 -----KVHA------FALDVDTTAVHFTCNIKMLFKDHEQCQRPRCG-NQRRFSRYLN 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532	5/11 (45%)
		PAN_1	294..373	CDD:278453	13/82 (16%)
		ZP	381..615	CDD:214579	19/73 (26%)
T01D1.8	NP_001300591.1	Zona_pellucida	<39..179	CDD:391783	34/175 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910