DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and CG42326

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001286200.1	Gene:	CG42326 / 35838	FlyBaseID:	FBgn0259226	Length:	1376	Species:	Drosophila melanogaster

Alignment Length:	443	Identity:	97/443 - (21%)
Similarity:	158/443 - (35%)	Gaps:	141/443 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 FDLPAASDLSSSLGSEEDSIYYDN----------------APVDCNPEL-VGFEI---VTGYVFS 129
            |.|.|....|:|:.|...|.|.|:                .|.:|:.:. .||.:   ...:.::
  Fly   827 FQLGAPHRESNSVLSYPGSGYEDDYPRRRNDYRQQWTRRAGPDECSAKTSEGFRLHKTAVRHAYN 891

  Fly   130 APEKLMDSQPGTLMLTDCLDTC---RKNKTCQSVNY---ETGL--CVLFSAHADQLPGALTKSQF 186
            .|           .||:|...|   |.:..|.:.:|   :.|.  |:|.....:.|...:.....
  Fly   892 VP-----------TLTECERLCSDPRPSFVCHTFSYRYNQAGRDNCMLCDRPINMLDYYVDIEPD 945

  Fly   187 PVFTIYAQKSCLAV--KPCSR-------AWYVDRVQNYK-----------LKTEVKRTVSVASRR 231
            ..:.||:....:.|  :|..|       :..:...:|.:           .|:.|:.:::|.|..
  Fly   946 RDYDIYSMADDMDVCRQPPPRRHDTAGPSTAISDPRNAQCFFRAIDATRFFKSIVRDSLTVRSVG 1010

  Fly   232 ECFELCLGENDFTCRSANY----DRTSGA---CELS-----ELDR---LTLAGSQAFQVNDGSDY 281
            ||...|:....||||:..:    .|.:|.   |:||     ::|:   |.|  ..||.:.:.:.|
  Fly  1011 ECEMECIRSTKFTCRAFAFRYGQQRHAGVIDNCQLSDWPVRDMDKERHLIL--DAAFDIFERASY 1073

  Fly   282 LENH-C-----VDEPN-KLCEF-KRLPGRIL----KTVDSVYQEVSSIDECRELCLNSPYRCHSY 334
              .| |     |||.: |||.. ...|.|:|    |.|.||..|::...||......:|::|.::
  Fly  1074 --GHGCEIQPIVDEKHKKLCYLGYGSPARLLPPAIKKVISVPSEIACKKECIRFRETTPFKCFAF 1136

  Fly   335 DYNDTGDMVCRLSHHS--RATLADVQEPFL--EVPEASTYELT-----------SCYNVTIECGG 384
            .|.         ||.|  ...|:|:.:..|  :|..|.|.:..           :|.:.....||
  Fly  1137 SYG---------SHASSFNCELSDLDQTELKQDVHYAHTKDRDFWLFAWNPFDWTCRDKVNTIGG 1192

  Fly   385 ---------------GDMLARIRTSKLFNGKVYAKGSP---------KSCSVD 413
                           ||:..|..|   .:||...:.||         .||..|
  Fly  1193 SRVNNDRRMDIFREPGDVAWRHYT---VSGKPCRRSSPCAKNLITGFYSCETD 1242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	15/87 (17%)
		PAN_AP_HGF	211..285	CDD:238532	23/99 (23%)
		PAN_1	294..373	CDD:278453	23/87 (26%)
		ZP	381..615	CDD:214579	13/57 (23%)
CG42326	NP_001286200.1	PAN_AP	44..>104	CDD:214680
		PAN_AP_HGF	468..560	CDD:238532
		PAN_AP_HGF	870..953	CDD:238532	17/93 (18%)
		PAN_AP_HGF	984..1070	CDD:238532	21/87 (24%)
		PAN_APPLE	1100..1168	CDD:294081	21/76 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47327
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100