DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment neo and pot

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001245635.1	Gene:	pot / 32154	FlyBaseID:	FBgn0250871	Length:	963	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	78/431 - (18%)
Similarity:	144/431 - (33%)	Gaps:	110/431 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 LSELDRLTLAGSQAFQVN-----DGSDYLENHCVDEPNKLCEFKRLPGRILKTVDSVYQEVSSID 318
            |:.|..:.|||..|.|.|     |..:|..|...:|               .|:|.   :|:.:|
  Fly    18 LAALLLICLAGQTAAQSNYVQHGDSGNYTTNGLPEE---------------ATLDG---KVTKLD 64

  Fly   319 ECRELCLNSPYRCHSYDYNDTGDMVCRLSHHSRATLADVQEPFLEVPEASTYELTSCYNVTIECG 383
            :...|.                                    ||...:|:           :.|.
  Fly    65 DISPLI------------------------------------FLNRTKAA-----------LNCA 82

  Fly   384 GGDMLARIRTSKLFNGKVYAKGSPKS-CSVDVKSALDFELRMNYHDLECNVRQSTAGRYVNDIII 447
            .|.|...::.:..|:|.:.|.....| |.|..|.||.:.|.:....  |...|:....:.|:||:
  Fly    83 AGSMQVDLKFNDPFHGIIQADYDRSSACRVSGKGALSYRLELPLKG--CGTIQNPTRVFTNNIIV 145

  Fly   448 QHHDMIVTSSDLGLALACQYDLTNKSVSNGVDLDVRGDIMPALSEEVIVESPNVIMRITSRDGSD 512
            :.|..:....|..:.:.|:|.....|:...:...:...|..:...:..::|..::|.|.:
  Fly   146 RFHANLEMDGDEIITIVCRYPPPVPSLPPALPAPILNPIATSSVLQPPLKSIQILMIICA----- 205

  Fly   513 MMRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEITLIDSNG-----------CPTDH 566
            :|....:...||:.:..:..:|   |.:...:.|.....||||.:..:.           .|..|
  Fly   206 IMFLTLLLLGLAVSYYCLRSRS---IPVVRRLPMSMGSGSEITKLSGSSVGNISAFEGVKIPRAH 267

  Fly   567 FIMGPIYKGSVS-GKMLLSNFDAFKFPSSEVVQFRALVTPCMPSCEPVQCEQEDTSGEFRSLLSY 630
            ..:..:|..|.| |.::.|:     :||....:...:.|..:|.......|......|..|:.|
  Fly   268 AALQAVYSSSGSEGALIPSD-----YPSESHSEIEEIDTRSLPFSSAGSFENRAFVHETSSIYS- 326

  Fly   631 GRKRRSLNTTDDHPRPRRDIDTSKKSAPSDMLLVQSIQITD 671
                       ||..|.:::.::.....:..:...||.|.:
  Fly   327 -----------DHYAPAQEMPSANAVMTTTSVTRHSIPIQE 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532	10/30 (33%)
		PAN_1	294..373	CDD:278453	8/78 (10%)
		ZP	381..615	CDD:214579	48/246 (20%)
pot	NP_001245635.1	ZP	81..>201	CDD:214579	25/121 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910