DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-4

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_507484.3	Gene:	cutl-4 / 189246	WormBaseID:	WBGene00012304	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	377	Identity:	80/377 - (21%)
Similarity:	142/377 - (37%)	Gaps:	82/377 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 SHHSRATLADVQEPFLEVPEASTYELTSCYNVTIECGGGDMLARIRTSKLFNGKVYAKG--SPKS 409
            ||...|.:..:|...:..||             :.|....:...:|||:.|.|.:|:||  ....
Worm    14 SHIQSAKVPRIQNGIVGEPE-------------VICDIKQIRITMRTSQSFIGNLYSKGFFHKSE 65

  Fly   410 CSV---DVKSALDFELRMNYHDLECNVRQSTAGRYVND--------IIIQHHDMIVTSSDLGLAL 463
            |.|   ...::::..|.:   |.:|.:|:.   |.:|.        :|:..|.:.:|.:|....:
Worm    66 CRVRGNSTANSIEIVLPV---DSDCGIRRK---RMMNPRGILLDTIVILMFHPVFLTQTDRSYHV 124

  Fly   464 ACQYDLTNKSVSNGVDLDVR-------------GDIMPALSEEVIVESPNVIMRITSRDGSDMMR 515
            .|||..:.::|:|.:|:.::             .|..|....||::|:..          ...:.
Worm   125 QCQYTESERTVTNALDVSMQPASELPQSIQQLNDDSAPVCKYEVLMENAQ----------GPPLS 179

  Fly   516 SAEVGDPLALKFEI-VDEQSPYEIFIRELVAMDGVDNSEITLIDSNGCPTDHFIMGPI---YKGS 576
            .|.|||.:..|:.. .:.:..|.:.:...|..||....: .|:|.:||..|.||:..:   .|..
Worm   180 HATVGDLVYHKWSCDGNNKEMYCMTVHSCVVDDGQGFGQ-KLVDEHGCTLDAFILKELEYNEKEL 243

  Fly   577 VSGKMLLSNFDAFKFPSSEVVQFRALV------TPCMPSCEPVQCEQEDTSGEFRSLLSYGRKRR 635
            .:|:|    ...|||.....|.|..::      :..||...|.:..:...|.:.::|.....::.
Worm   244 EAGQM----SSVFKFADKPTVFFSCMIRVEMKESAEMPCVIPTEVCKNLPSSKMQNLDVMTDRKV 304

  Fly   636 SLNTTDDHPRPRRDIDTSKKSAPSDMLLVQSIQITDKFGFKQDKQESGDFYD 687
            |.:.....|||:.:....|....|          ||......|  .|.||.|
Worm   305 SDDIPPGFPRPQNNTKLQKSQKFS----------TDAMTSNSD--YSADFLD 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453	6/25 (24%)
		ZP	381..615	CDD:214579	59/269 (22%)
cutl-4	NP_507484.3	ZP	35..278	CDD:214579	57/263 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910