DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neo and cutl-12

DIOPT Version :9

Sequence 1:	NP_651733.1	Gene:	neo / 43523	FlyBaseID:	FBgn0039704	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001309578.1	Gene:	cutl-12 / 188735	WormBaseID:	WBGene00011928	Length:	569	Species:	Caenorhabditis elegans

Alignment Length:	393	Identity:	87/393 - (22%)
Similarity:	141/393 - (35%)	Gaps:	83/393 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 IECGGGDMLARIRTSKLFNGKVYAKG-SPKS-CSVDVKSAL-------DFELRMNYHDLECNVRQ 435
            :|||...:...|..:..|.|.||.:| .|:: |.::..:.|       |...|.     .||||:
Worm    36 LECGSEGIRLHINPTGTFGGHVYVRGFFPQTVCHLNYCTRLTNRPIVMDLPFRG-----PCNVRR 95

  Fly   436 -----STAGRYVNDIIIQHHDMIVTSSDLGLALACQYDLTNKSVSNGVDL-DVRGDIM-----PA 489
                 ..:..|...:|||||.:.|||.|....|.|.|.....::...::: |:....:     |.
Worm    96 RRNVAPPSISYDVTVIIQHHPLFVTSFDKAYRLNCIYRQQESTLQQRINVSDIPSTALQSKNAPK 160

  Fly   490 LSEEVIVESPNVIMRITSRDGSDMMRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNSEI 554
            ...:|:..|.|          ..::|.|.|||.:..|:..  :...:...:...|..| ....:.
Worm   161 CRYDVLSGSLN----------GPVVRFANVGDVVVHKWTC--DSDRFGFVVHSCVVRD-ESGKDF 212

  Fly   555 TLIDSNGCPTDHFIMGPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTPCM-----------P 608
            ..||..||.|| |.:.|....|...|...:...||::....:|.|...:|.|.           |
Worm   213 QFIDERGCVTD-FSLFPEVSYSDDLKSAFTAVRAFRYADQVMVHFSCQITTCQKQENGCEGISPP 276

  Fly   609 SCEPVQC--------------EQEDTSGEFRSL------LSYGRKRRSLNTTDDHPRPRRDIDTS 653
            .|.|:..              |:.|..|...:|      .|.| ...::.:|....|.:....|:
Worm   277 ICRPMDLGPIKVHYVKHEKNGEKFDEGGGVETLPPRTENTSEG-STTTVRSTTTRERAQAFSTTT 340

  Fly   654 KKSAPSDMLLVQSIQ---------ITDKF--GFKQDKQESGD-FYDGNETTFTANEEGHGFCVNA 706
            .|:..|..|.::::|         .:.||  |:.....|||: ....|...|....:.....||.
Worm   341 HKTTTSSSLQLKTVQRDEDNNSFSPSSKFRNGYNFPNVESGEGVGQDNTAEFGVKRKSSDAGVNE 405

  Fly   707 IGL 709
            .|:
Worm   406 YGI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453
		PAN_AP_HGF	211..285	CDD:238532
		PAN_1	294..373	CDD:278453
		ZP	381..615	CDD:214579	63/264 (24%)
cutl-12	NP_001309578.1	ZP	37..281	CDD:214579	62/262 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910