Protein Alignment neo and cutl-17

DIOPT Version :9

• Sequence 1: NP_651733.1
• Gene: neo / 43523
• FlyBaseID: FBgn0039704
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_001379101.1
• Gene: cutl-17 / 185474
• WormBaseID: WBGene00009541
• Length: 912
• Species: Caenorhabditis elegans
• Alignment Length: 853
• Identity: 171/853 - (20%)
• Similarity: 307/853 - (35%)
• Gaps: 265/853 - (31%)

  Fly    35 SVTAAAPNASKVMASEEIKDKTEWPGAKETSTEINRTERPVENVETRNSGFDLPAASDLSSSLGS 99
            |...:||||:..:.||..:       ..|.||::      :::| |.|.     .|:..|:||.:
 Worm    17 SSRCSAPNATTYLRSEGTR-------LMEFSTKV------MKDV-TLNE-----CANACSNSLST 62

  Fly   100 EED-SIYYDNAPVDCN-----------------PELVGFE----IVTGYVFSAPEKLMDSQPGTL 142
            ||. |..||.:.:.|:                 .:.:.|.    ::...|..||.. .:..|.::
 Worm    63 EECLSFEYDASILQCSHHSDDGQPFGASVLAKASQTISFFQQICLLEEAVCKAPYS-FERYPQSI 126

  Fly   143 M------------LTDCLDTCRKNK-----TCQSV--NYETGLCVLFSAHADQLPGALTKSQFPV 188
            :            |:|||..|..::     .|:|.  .||||.|::...:....|.....:....
 Worm   127 LIGHAMKVLTVDGLSDCLSKCALSQRSYDFLCKSAIYYYETGECIMNRDNKFIYPKLFKTNILDT 191

  Fly   189 FTIYAQKSC--LAVKPCSRAWYVDRVQNYKLKTEVKRTVSVASRRECFELC----LGENDFTCRS 247
            ...|.:.:|  ::.||.....:| |.:.|.:.......|..:..:||.:||    :||.:|.|::
 Worm   192 LVDYFENNCADVSCKPEETLHWV-RTEEYLIDESKDVIVESSDAQECNQLCQNNKIGEENFPCKA 255

  Fly   248 ANYDRTSGACEL-SELDRLTLAGSQAFQ---VNDGSDYLENHCVDEPNKL----CEFKRLPGRIL 304
            ..|..:...|.| :|...:...|.:.|.   :|.| :|.|.:|:  |..|    ..|:.:..|::
 Worm   256 FAYSNSKQECHLTAESSYVGHKGDKRFNLAPLNSG-EYFEKYCL--PTNLQCIEASFELVANRMM 317

  Fly   305 KTVDSVYQEVSSID--ECRELCLNSPYRCHS--YDYNDTGDMVCRLSHHSR------ATLADV-- 357
               .|.|:.:|::.  ||...|:|...||.|  |.|.|....:..:|..||      |...|.
 Worm   318 ---TSAYKTISALSQHECLSQCMNDGARCSSATYFYMDDECQLSDISQFSRPNEFVVANFTDYFD 379

  Fly   358 -------QEPFLEVPE------------------------ASTYE-------------------- 371
                   .:|.|..||                        |:.:|
 Worm   380 KICDPADPKPMLTTPETPPELIQNSVDEEETTSERSIAQGAANFEVATTGTSVEFEDDNLLKDNQ 444

  Fly   372 -------LTSCYNV------------------------------------------------TIE 381
                   :|:..|:                                                :.|
 Worm   445 AVDAVHGVTTTTNIGEKRETKVEIEETVIDDADEFSREIDDSHEESPLTSSEESEGRVKARLSTE 509

  Fly   382 CGGGDMLARIRTSKLFNGKVYAKGSPKSCSVDVKSALDFELRMNY---HDLECNVRQSTAGRYVN 443
            |....:...::.:...:|.:|.|....||.....:....||.:.:   .|.:|...:|...::..
 Worm   510 CRMSGISVSLKFATPTSGTIYIKDHFSSCRQSFSNTSFAELHIPFPTEDDSKCGGIESEPHKWDY 574

  Fly   444 DIIIQHHDM----IVTSSDLGLALACQYD-LTNKSVSNGVDLDVRGDIMPALSEEVIVESPNVIM 503
            :::::.:||    :||:.|....::|.:. :.:|:....:...|.||          |:|..|:|
 Worm   575 NVVVERNDMKTPSLVTTKDKTFQVSCDFSKIADKNQLAALKPKVEGD----------VKSEKVLM 629

  Fly   504 RITSRDGSDMMRSAEVGDPLALKFEIVDEQSPYEIFIRELVAMDGVDNS----EITLIDSNGCPT 564
            .|. |:| ..:.:..:|..::|::.::||......||.|.:| :.|...    |...|...|||.
 Worm   630 EIV-RNG-QAVTTVPLGAEVSLRWTVIDETDKLGFFINECIA-ERVGGQPPYPEPLKIIYQGCPE 691

  Fly   565 D----HFIMGPIYKGSVSGKMLLSNFDAFKFPSSEVVQFRALVTPCMPSCEPVQCEQEDTSGEFR 625
            :    ..:..|:.|   :|::..:....|:|..|..|:.:..:..|:..|.||.|:..    |.|
 Worm   692 EKVRNRLLHDPVVK---NGEVYSTKMKVFRFDGSRRVRIKCSIDVCVEKCPPVICDDL----EIR 749

  Fly   626 SLLSYGRKRRSLNT------------------------TDDHP-----RPRRDIDTSKKSAPSDM 661
            ::.|:|||:|:.|.                        ||:..     :||.:..||..|:....
 Worm   750 NVDSFGRKKRNSNVEKWLKAGNKKETRKRRMVTGTLTITDEEETNTTVKPRPEFSTSSSSSSQQQ 814

  Fly   662 LLVQSIQI 669
            ..||..:|
 Worm   815 YCVQKDRI 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
neo	NP_651733.1	PAN_1	120..197	CDD:278453	19/99 (19%)
		PAN_AP_HGF	211..285	CDD:238532	21/81 (26%)
		PAN_1	294..373	CDD:278453	26/148 (18%)
		ZP	381..615	CDD:214579	54/249 (22%)
cutl-17	NP_001379101.1	PAN_1	26..106	CDD:394981	19/98 (19%)
		PAN_AP_HGF	114..199	CDD:238532	17/85 (20%)
		PAN_AP	208..295	CDD:214680	21/88 (24%)
		PAN_AP_HGF	308..380	CDD:238532	20/74 (27%)
		Zona_pellucida	509..744	CDD:421542	54/250 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	78	1.000	Domainoid score	I5679
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.970